Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Iain S. Hunter"'
Autor:
Charlotte Hind, Melanie Clifford, Charlotte Woolley, Jane Harmer, Leah M. C. McGee, Izaak Tyson-Hirst, Henry J. Tait, Daniel P. Brooke, Stephanie J. Dancer, Iain S. Hunter, Colin J. Suckling, Rebecca Beveridge, John A. Parkinson, J. Mark Sutton, Fraser J. Scott
Publikováno v:
ACS Infectious Diseases. 8:2552-2563
MGB-BP-3 is a potential first-in-class antibiotic, a Strathclyde Minor Groove Binder (S-MGB), that has successfully completed Phase IIa clinical trials for the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd40ee75d50fe78bef77a7f42c5f6f2
https://doi.org/10.1021/acsinfecdis.2c00445
https://doi.org/10.1021/acsinfecdis.2c00445
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218185 (2019)
Multi-locus sequencing typing (MLST) is widely used to monitor the phylogeny of microbial outbreaks. However, several strains of vancomycin-resistant Enterococcus faecium (VREfm) with a missing MLST locus (pstS) have recently emerged in Australia, wi
Externí odkaz:
https://doaj.org/article/b8350ff58f234db0be8f984f0db37e3e
Autor:
Jana K. Schniete, Pablo Cruz-Morales, Nelly Selem-Mojica, Lorena T. Fernández-Martínez, Iain S. Hunter, Francisco Barona-Gómez, Paul A. Hoskisson
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces bacteria are prolific producers of bioactive specialized metabolites that have adaptive functions i
Externí odkaz:
https://doaj.org/article/fa63f88793cd4fa6812bf72ef3840462
Publikováno v:
Biosensors, Vol 2, Iss 2, Pp 171-188 (2012)
Infection control is a key aspect of wound management strategies. Infection results in chemical imbalances and inflammation in the wound and may lead to prolonged healing times and degradation of the wound surface. Frequent changing of wound dressing
Externí odkaz:
https://doaj.org/article/2a96f15d6dda489faeb66cf8afc291ac
Publikováno v:
Microbial Genomics
Here, we characterize an uncommon set of telomeres from Streptomyces rimosus ATCC 10970, the parental strain of a lineage of one of the earliest-discovered antibiotic producers. Following the closure of its genome sequence, we compared unusual telome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc78adb5a1f74c9dce2641d9a2af7eb
https://pubmed.ncbi.nlm.nih.gov/34779763
https://pubmed.ncbi.nlm.nih.gov/34779763
Autor:
Iain S. Hunter, Colin J. Suckling, Kimon Lemonidis, Douglas F. Browning, Talal Salih, Leena Kerr, Nicholas P. Tucker
Rising levels of antibiotic resistance dictate that new antibiotics with novel modes of action must be found. Here, we investigated the mode of action of a novel antibiotic that is a member of a family of synthetic DNA minor groove binding (MGB) mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::125507c095c493e23379743a4398bd45
https://doi.org/10.1101/2020.12.31.424950
https://doi.org/10.1101/2020.12.31.424950
Autor:
Anna S. Birke, Francisco Barona-Gómez, Iain S. Hunter, Pablo Cruz-Morales, Nelly Selem-Mojica, Paul A. Hoskisson, Jana K. Schniete
Publikováno v:
Microbial Genomics
Actinobacteriaare a large and diverse phylum of bacteria that contains medically and ecologically relevant organisms. Many members are valuable sources of bioactive natural products and chemical precursors that are exploited in the clinic. These are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56493f568541892f0e949be144473e18
http://europepmc.org/articles/PMC8115908
http://europepmc.org/articles/PMC8115908
Autor:
Iain S. Hunter, Paul Herron, Paul A. Hoskisson, Jana K. Schniete, Leena Kerr, Nicholas P. Tucker, Richard Reumerman
Background. Streptomycete bacteria are prolific producers of specialized metabolites, many of which have clinically relevant bioactivity. A striking feature of their genomes is the expansion of gene families that encode the same enzymatic function. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801035c80a6ebefb8d1a47b2182320fe
https://strathprints.strath.ac.uk/71682/7/Schniete_etal_AM_2020_Differential_transcription_of_expanded_gene_families_in_central_carbon_metabolism.pdf
https://strathprints.strath.ac.uk/71682/7/Schniete_etal_AM_2020_Differential_transcription_of_expanded_gene_families_in_central_carbon_metabolism.pdf
Autor:
Jana K, Schniete, Richard, Reumerman, Leena, Kerr, Nicholas P, Tucker, Iain S, Hunter, Paul R, Herron, Paul A, Hoskisson
Publikováno v:
Access Microbiology
Background Streptomycete bacteria are prolific producers of specialized metabolites, many of which have clinically relevant bioactivity. A striking feature of their genomes is the expansion of gene families that encode the same enzymatic function. Ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cdc0663d23e87d468559ab9ed278c5f
https://pubmed.ncbi.nlm.nih.gov/32974587
https://pubmed.ncbi.nlm.nih.gov/32974587
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218185 (2019)
PLoS ONE
PLoS ONE
Multi-locus sequencing typing (MLST) is widely used to monitor the phylogeny of microbial outbreaks. However, several strains of vancomycin-resistant Enterococcus faecium (VREfm) with a missing MLST locus (pstS) have recently emerged in Australia, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1923d306b72a2c7f6859502ccb14306d
https://strathprints.strath.ac.uk/68910/1/Lemonidis_etal_PLoS_One_2019_Emergence_of_an_Australian_like_pstS_null_vancomycin_resistant_enterococcus_faecium_clone_in_Scotland.pdf
https://strathprints.strath.ac.uk/68910/1/Lemonidis_etal_PLoS_One_2019_Emergence_of_an_Australian_like_pstS_null_vancomycin_resistant_enterococcus_faecium_clone_in_Scotland.pdf