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SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke–Korsakoff’s Syndrome

Autor: Niamh L, O'Brien, Giorgia, Quadri, Iain, Lightley, Sally I, Sharp, Irene, Guerrini, Iain, Smith, Mathis, Heydtmann, Marsha Y, Morgan, Allan D, Thomson, Nicholas J, Bass, Patrick C, McHugh, Andrew, McQuillin

Publikováno v: Alcohol and Alcoholism. 57:581-588

Aims Wernicke–Korsakoff syndrome (WKS) is commonly associated with chronic alcohol misuse, a condition known to have multiple detrimental effects on thiamine metabolism. This study was conducted to identify genetic variants that may contribute to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221163951a4612a8b95e3bddb3483f25
https://doi.org/10.1093/alcalc/agac032

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Artificial Intelligence Approaches to Build Ticket to Ride Maps

Autor: Iain Smith, Calin Anton

Publikováno v: Proceedings of the AAAI Conference on Artificial Intelligence. 36:12844-12851

Fun, as a game trait, is challenging to evaluate. Previous research explores game arc and game refinement to improve the quality of games. Fun, for some players, is having an even chance to win while executing their strategy. To explore this, we buil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::353c40b2eee3457e13fd7b0932789e54
https://doi.org/10.1609/aaai.v36i11.21564

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Alcohol minimum unit pricing and people experiencing homelessness: A qualitative study of stakeholders' perspectives and experiences

Autor: Elena D. Dimova, Heather Strachan, Sarah Johnsen, Carol Emslie, Martin Whiteford, Robert Rush, Iain Smith, Tim Stockwell, Anne Whittaker, Lawrie Elliott

Publikováno v: Drug and alcohol reviewREFERENCES. 42(1)

Minimum unit pricing (MUP) may reduce harmful drinking in the general population, but there is little evidence regarding its impact on marginalised groups. Our study is the first to explore the perceptions of MUP among stakeholders working with peopl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a88a02f2d303c9e97e06f6aa80789bf
https://pubmed.ncbi.nlm.nih.gov/36169446

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The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses

Autor: Andrew McQuillin, M. Heydtmann, Wenqianglong Li, Niamh L. O'Brien, Iain Smith, Nicholas Bass, Markus M. Nöthen, Franziska Degenhardt, Marsha Y. Morgan, Johan H. Thygesen

Publikováno v: Psychiatric Genetics. 31:13-20

Introduction Genome-wide association studies (GWAS) of alcohol dependence syndrome (ADS) offer a platform to detect genetic risk loci. However, the majority of the ADS GWAS undertaken, to date, have utilized a case-control design and have failed to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e95cafad183b782f4ee2c553aa3f00
https://doi.org/10.1097/ypg.0000000000000268

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Adapting Lean methods to facilitate stakeholder engagement and co-design in healthcare

Autor: Chris Hicks, Thomas H. McGovern, Iain Smith

Publikováno v: The BMJ

Quality improvement approaches drawn from industry can go beyond traditional concepts of value and deliver improvements in healthcare services, argue Iain Smith and colleagues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda95b8c9f9160072bb4fd32e9f2ffcc
http://europepmc.org/articles/PMC7190378

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20Media

Autor: Iain Smith

Publikováno v: The Year's Work in Critical and Cultural Theory. 26:388-409

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b557d7b65159fa272e300a8384774c4d
https://doi.org/10.1093/ywcct/mby021

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