Zobrazeno 1 - 10
of 115
pro vyhledávání: '"IVD degeneration"'
Autor:
RJ Williams, S Basatvat, TC Schmitz, R Janani, C Sammon, K Benz, K Ito, MA Tryfonidou, JW Snuggs, CL Le Maitre
Publikováno v:
European Cells & Materials, Vol 47, Pp 30-50 (2024)
Low back pain is the leading cause of disability worldwide and is strongly associated with degeneration of the intervertebral disc (IVD). During degeneration the nucleus pulposus (NP) in the core of the IVD, is affected by altered matrix synthesis, i
Externí odkaz:
https://doaj.org/article/ecbc35f4d0e5464bbf9c46ac76159d58
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 3, Pp n/a-n/a (2024)
Abstract Intervertebral disc (IVD) degeneration is a common phenomenon that affects patients with increasing prevalence with increasing age. Both conservative treatments, such as the use of pain medication or physical therapy, and surgical treatments
Externí odkaz:
https://doaj.org/article/0c7c8582ddea413ead7399e07cf45cc1
Autor:
Isma Liza Mohd Isa, Izzat Zulkiflee, Raed H. Ogaili, Nurul Huda Mohd Yusoff, Natasya Nadia Sahruddin, Shaiful Ridzwan Sapri, Elvy Suhana Mohd Ramli, Mh Busra Fauzi, Sabarul Afian Mokhtar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: A regenerative strategy employing extracellular matrix (ECM)-based biomaterials and stem cells provide a better approach to mimicking the three-dimensional (3D) microenvironment of intervertebral disc for endogenous tissue regeneration.
Externí odkaz:
https://doaj.org/article/9d78df3629a945fa9708de0e9d1d0c33
Akademický článek
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Autor:
Jiaxin Chen, Haifeng Zhu, Yutao Zhu, Chenchen Zhao, Shengyu Wang, Yixin Zheng, Ziang Xie, Yang Jin, Honghai Song, Linjun Yang, Jin Zhang, Jiayong Dai, Zhijun Hu, Huaiyu Wang
Publikováno v:
Bioactive Materials, Vol 9, Iss , Pp 29-43 (2022)
Inflammatory responses of nucleus pulposus (NP) can induce imbalanced anabolism and catabolism of extracellular matrix, and the cytosolic dsDNA accumulation and STING–NF–κB pathway activation found in NP inflammation are considered as fairly imp
Externí odkaz:
https://doaj.org/article/c6e559159e6d4f23ac0cecd291c839b2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: Whole body vibration (WBV) has been used to treat various musculoskeletal diseases in recent years. However, there is limited knowledge about its effects on the lumbar segments in upright posture mice. This study was performed to investig
Externí odkaz:
https://doaj.org/article/8fed64e650c446a490312dfb71032696
Autor:
Marco A. Herrera Quijano, Nadia Sharma, Pascal Morissette Martin, Cheryle A. Séguin, Lauren E. Flynn
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Bioscaffolds derived from the extracellular matrix (ECM) have shown the capacity to promote regeneration by providing tissue-specific biological instructive cues that can enhance cell survival and direct lineage-specific differentiation. This study f
Externí odkaz:
https://doaj.org/article/dcbd6cf11b2b482ca0dca4524b300500
Autor:
Lin Lu, Aoshuang Xu, Fei Gao, Chenjun Tian, Honglin Wang, Jiayao Zhang, Yi Xie, Pengran Liu, Songxiang Liu, Cao Yang, Zhewei Ye, Xinghuo Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Intervertebral disc degeneration (IVDD) has been reported to be the most prevalent contributor to low back pain, posing a significant strain on the healthcare systems on a global scale. Currently, there are no approved therapies available for the pre
Externí odkaz:
https://doaj.org/article/2bb289b236fc4b41ad4d92e37ded3aaa
Autor:
Cheol Ho Heo, Eun Ji Roh, Jaehee Kim, Hyemin Choi, Ho Yeon Jang, Giseong Lee, Chang Su Lim, Inbo Han
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 4, p 192 (2023)
Cyclooxygenase-2 (COX-2) is a biomolecule known to be overexpressed in inflammation. Therefore, it has been considered a diagnostically useful marker in numerous studies. In this study, we attempted to assess the correlation between COX-2 expression
Externí odkaz:
https://doaj.org/article/11b8ddc8871f425997a35106d652dffb
Akademický článek
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