Zobrazeno 1 - 10
of 14
pro vyhledávání: '"ITZHAK NUSSINOVITCH"'
Autor:
Itzhak Nussinovitch
Publikováno v:
Endocrinology. 159:4043-4055
Ca2+ influx through voltage-gated Ca2+ channels (VGCCs) plays a key role in GH secretion. In this review, we summarize the current state of knowledge regarding the physiology and molecular machinery of VGCCs in pituitary somatotrophs. We next discuss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c458095764ba737d875af888ad8d5b97
https://doi.org/10.1210/en.2018-00743
https://doi.org/10.1210/en.2018-00743
Publikováno v:
Cell Calcium. 47:514-524
Voltage-gated calcium channels (VGCCs) are osmosensitive. The hypothesis that this property of VGCCs stems from their susceptibility to alterations in the mechanical properties of the bilayer was tested on VGCCs in pituitary cells using cone-shaped l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b58fe7f16e93f2e27ec00e29916a364
https://doi.org/10.1016/j.ceca.2010.04.006
https://doi.org/10.1016/j.ceca.2010.04.006
Publikováno v:
Journal of Neurochemistry. 97:116-127
The coupling of voltage-gated Ca2+ channel (VGCC) to exocytotic proteins suggests a regulatory function for the channel in depolarization-evoked exocytosis. To explore this possibility we have examined catecholamine secretion in PC12 and chromaffin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab83766ac40ec9d637217cc704fbe72
https://doi.org/10.1111/j.1471-4159.2006.03709.x
https://doi.org/10.1111/j.1471-4159.2006.03709.x
Publikováno v:
Nature Neuroscience. 2:440-446
Using FM1-43 fluorescence, we have optically detected single exocytic and endocytic events in rat pituitary lactotrophs. About fifty discrete fluorescent spots abruptly appear around the entire surface of a cell bathed in FM1-43 and high-potassium sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd811f77568f9d9a1537032f6e81181
https://doi.org/10.1038/8107
https://doi.org/10.1038/8107
Publikováno v:
Journal of Neurophysiology. 75:1894-1900
1. The sensitivity of voltage-gated calcium currents to hyperosmotic media containing mannitol or sucrose (373-723 mOsm) and to the dihydropyridine (DHP) calcium channel agonist Bay K 8644 was examined in enriched populations of rat anterior pituitar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45ed50a4a0e5fd3a0022d4c0331c8e1
https://doi.org/10.1152/jn.1996.75.5.1894
https://doi.org/10.1152/jn.1996.75.5.1894
Publikováno v:
American journal of physiology. Cell physiology. 290(1)
Increased extracellular osmolarity ([Os]e) suppresses stimulated hormone secretion from anterior pituitary cells. Ca2+ influx may mediate this effect. We show that increase in [Os]e (by 18–125%) differentially suppresses L-type and T-type Ca2+ chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7655a63a92e31f999fb36d06b54b6d41
https://pubmed.ncbi.nlm.nih.gov/16148035
https://pubmed.ncbi.nlm.nih.gov/16148035
Publikováno v:
The Journal of physiology. 532(Pt 3)
We studied the relationship between exocytosis and endocytosis in rat pituitary somatotrophs using patch-clamp capacitance, FM1-43 fluorescence imaging and amperometry. Stimulation of exocytosis through voltage-dependent Ca2+ channels by depolarizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ed5686b9160a4d76fac7dcd631e77a
https://pubmed.ncbi.nlm.nih.gov/11313445
https://pubmed.ncbi.nlm.nih.gov/11313445
Autor:
E. Keller, Itzhak Nussinovitch
Publikováno v:
Journal of neurophysiology. 76(4)
1. The inactivation of high-voltage-activated (HVA) calcium currents during long depolarizations in holding potential (Vh) was studied with the use of whole cell patch-clamp recording from rat anterior pituitary cells. 2. An ultra-slow inactivation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555d6c89473a58f4180043c2d9d46de1
https://pubmed.ncbi.nlm.nih.gov/8899591
https://pubmed.ncbi.nlm.nih.gov/8899591
Autor:
Anna L. Kleinhaus, Itzhak Nussinovitch
Publikováno v:
Brain research. 574(1-2)
Several lines of evidence suggest that dopamine acts as a neurotransmitter that inhibits both hormone secretion and electrical activity in pituitary intermediate cells (melanotrophs). In this study we examined the effects of exogenously applied dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593a26612e4939e809b27b358f2222ba
https://pubmed.ncbi.nlm.nih.gov/1322227
https://pubmed.ncbi.nlm.nih.gov/1322227
Publikováno v:
Journal of Neurophysiology; May1996, Vol. 75 Issue 5, p1894-1900, 7p