Zobrazeno 1 - 10
of 103
pro vyhledávání: '"ITM2A"'
Autor:
Xiaoxia Zeng, Dunhui Yang, Jin Zhang, Kang Li, Xijia Wang, Fang Ma, Xianqin Liao, Zhen Wang, Xianhai Zeng, Peng Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Head and neck squamous carcinoma (HNSC), characterized by a high degree of malignancy, develops in close association with the tumor immune microenvironment (TIME). Therefore, identifying effective targets related to HNSC and TIME is of paramount impo
Externí odkaz:
https://doaj.org/article/2f11de91f93a44f0823782191f724b9f
Autor:
Céline Cegarra, C. Chaves, C. Déon, T. M. Do, B. Dumas, A. Frenzel, P. Kuhn, V. Roudieres, J. C. Guillemot, D. Lesuisse
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Integral membrane protein 2A (ITM2A) is a transmembrane protein expressed in a variety of tissues; little is known about its function, particularly in the brain. ITM2A was found to be highly enriched in human brain versus peripher
Externí odkaz:
https://doaj.org/article/22121e1b061a42618c7366aa52bf77f3
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Background Autoimmune thyroid disease (AITD) manifests with a female predominance, and much attention has been directed towards the integral membrane protein 2 A (ITM2A) gene located on the X chromosome. Methods In a study of 166 pediatric p
Externí odkaz:
https://doaj.org/article/2c5ca143eff447159db8f70b558830b4
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Ankylosing spondylitis (AS) is a rare inflammatory disorder affecting the spinal joints. Although we know some of the genetic factors that are associated with the disease, the molecular basis of this illness has not yet been fully
Externí odkaz:
https://doaj.org/article/a280615c39194e1b96dd449a3aba6052
Publikováno v:
Contemporary Oncology, Vol 24, Iss 2, Pp 87-95 (2020)
Externí odkaz:
https://doaj.org/article/50e00c2c029742c6804114209c1a5646
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Breast cancer is a life-threatening disease in females and the leading cause of mortality among the female population, presenting huge challenges for prognosis and treatment. ITM2A is a member of the BRICHOS superfamily, which are
Externí odkaz:
https://doaj.org/article/329a8ae8625b4d3eb87334f76fb84f7a
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundHigh expression of integral membrane protein 2A (ITM2A) was reported to be associated with favorable prognosis in several solid tumors including breast cancer. This study aimed to investigate the role of ITM2A in breast cancer, especially i
Externí odkaz:
https://doaj.org/article/533bbd518f004d42ac610f79e8ed43c0
Akademický článek
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Publikováno v:
Cells, Vol 10, Iss 8, p 2003 (2021)
The Hedgehog (Hh) receptor PTCH1 and the integral membrane protein 2A (ITM2A) inhibit autophagy by reducing autolysosome formation. In this study, we demonstrate that ITM2A physically interacts with PTCH1; however, the two proteins inhibit autophagic
Externí odkaz:
https://doaj.org/article/dbe133a7ee3a485c97f1740227b62750
Akademický článek
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