Zobrazeno 1 - 10
of 50
pro vyhledávání: '"ITGB7"'
Autor:
Sarah J. Potter, Li Zhang, Michael Kotliar, Yuehong Wu, Caitlin Schafer, Kurtis Stefan, Leandros Boukas, Dima Qu’d, Olaf Bodamer, Brittany N. Simpson, Artem Barski, Andrew W. Lindsley, Hans T. Bjornsson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Individuals with Kabuki syndrome present with immunodeficiency; however, how pathogenic variants in the gene encoding the histone-modifying enzyme lysine methyltransferase 2D (KMT2D) lead to immune alterations remain poorly understood. Following up o
Externí odkaz:
https://doaj.org/article/cf9678b7fb124e57af5f1be2328c292d
Autor:
Samrat Roy Choudhury, Stephanie D. Byrum, Duah Alkam, Cody Ashby, Fenghuang Zhan, Alan J. Tackett, Frits Van Rhee
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Oncogenic overexpression of integrin-β7 (ITGB7) in cases of high-risk multiple myeloma (MM) was reported to promote enhanced interactions between neoplastic plasma-B cells and stromal cells to develop cell-adhesion mediated drug
Externí odkaz:
https://doaj.org/article/da8930f7c5b643a592478ee5b0d59690
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Biology, Vol 10, Iss 11, p 1129 (2021)
Plaque psoriasis (PSO) and lichen planus (LP) are skin diseases with some similarities in pathogenesis, comorbidities, and clinical presentation. Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and its ligand, α4β7 integrin, are involved in i
Externí odkaz:
https://doaj.org/article/060788058e9c4fc49ee3f56cccaea6ae
Publikováno v:
Almanac of Clinical Medicine. 49:469-476
Background: Worldwide studies of genetic material, polymorphisms and prognostic gene models for immune-associated disorders have established differences in trans-ethnic population cohorts, which determine phenotypic and other characteristics of the c
Publikováno v:
Annals of Medicine
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Background The overall response rate of immunotherapy in triple-negative breast cancer (TNBC) remains unsatisfactory. Accumulating evidence indicated that glucose metabolic reprogramming could modulate immunotherapy efficacy. However, transcriptomic
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
The roles of different integrin alpha/beta (ITGA/ITGB) subunits in skin cutaneous melanoma (SKCM) and their underlying mechanisms of action remain unclear. Oncomine, UALCAN, GEPIA, STRING, GeneMANIA, cBioPortal, TIMER, TRRUST, and Webgestalt analysis
Autor:
Aida Habtezion, Yeneneh Haileselassie, Sidhartha R. Sinha, Arpita Sharma, Samuel J S Rubin, Akshar Patel, Tatiana Balabanis, Steven Levitte, Lawrence Bai, John Gubatan
Publikováno v:
J Crohns Colitis
Background and Aims Vitamin D downregulates the in vitro expression of the gut-tropic integrin α4β7 on immune cells. The clinical relevance of this finding in patients with inflammatory bowel disease [IBD] is unclear. We tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd0d3369b0a16d6bc6781146ee0cb45
https://europepmc.org/articles/PMC8684474/
https://europepmc.org/articles/PMC8684474/