Trastuzumab Deruxtecan for the Treatment of HER2-low Advanced or Metastatic Breast Cancer.

Autor: Toshinari Yamashita¹ tyamashita@kcch.jp

Publikováno v: touchREVIEWS in Oncology & Haematology. 2024, Vol. 20 Issue 1, p36-40. 5p.

Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut–Brain Axis

Autor: Noah F. Shroyer, Amy C. Engevik, Sridevi Devaraj, Bradley T. Endres, Berkley Luck, James Versalovic, Heather A. Danhof, Faith D. Ihekweazu, Anne Hall, Zhongcheng Shi, Chonnikant Visuthranukul, Kevin W. Garey, Anthony M. Haag, Robert A. Britton, Sigmund J. Haidacher, Melinda A. Engevik, Alexandra Chang-Graham, Joseph M. Hyser, Thomas D. Horvath

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 221-248 (2021)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood. Methods Adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f511aee01ee5a2ae18950cf2bea32bbc
https://doi.org/10.1016/j.jcmgh.2020.08.002

miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma

Autor: Chi Hou Ng, Mu Shiun Tsai, Mai Huong Thi Nguyen, Jean Lu, Ming Hong Chen, Shu Chen Liu, Nianhan Ma, Long Yuan Li, Jen Chieh Tsai, Chen Huan Lin, Hironobu Ihn, Hsuan Lin, Satoshi Fukushima, Azusa Miyashita, In Yu Lin, Szu Mam Liu

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 789-799 (2020)
Neoplasia (New York, N.Y.)

BRAF inhibitors were approved for the treatment of BRAF-mutant melanoma. However, most patients acquire the resistance to BRAF inhibitors after several months of treatment. miR-524-5p is considered as a tumor suppressor in many cancers, including mel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34d1c07ad9f7bf3140c025ea38a8d55
http://www.sciencedirect.com/science/article/pii/S1476558620301640

Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection

Autor: Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz

Publikováno v: Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344

Modelling cell infection in-a-dish can represent a useful tool to understand the susceptibility of different cell types towards severe acute respiratory coronavirus-2 (SARS-CoV-2) and to decipher its neurotropism. In this perspective, retinoic acid (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6b19eec2e5f936a29312b7975f27ca
https://researchportal.unamur.be/en/publications/b4334368-1063-4325-9db9-a5dc776e2c12

Histopathological features in fatal COVID-19 acute respiratory distress syndrome

Autor: Hamid Merdji, Malika Schenck, Sibylle Cunat, Ferhat Meziani, Ralf Janssen-Langenstein, J.-E. Herbrecht, Raphaël Clere-Jehl, M.-P. Chenard, S. Mayeur, Julie Helms, W. Oulehri, A. Nicolae

Publikováno v: Medicina Intensiva

COVID-19 acute respiratory distress syndrome (ARDS) shares the common histological hallmarks with other forms of ARDS. However, the chronology of the histological lesions has not been well established.To describe the chronological histopathological a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08495f9b8bf55ebb01fdd506f2a5a509
https://pubmed.ncbi.nlm.nih.gov/34054173