Zobrazeno 1 - 10
of 325
pro vyhledávání: '"ISAO KITAJIMA"'
Autor:
Shinya Ootsuki, Hideki Niimi, Tomohiro Ueno, Masashi Mori, Homare Tabata, Hiroshi Minami, Isao Kitajima
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Identifying pathogenic microorganisms as early as possible is critical for selecting the appropriate antimicrobial therapy in infected patients. We previously reported the development of the Tm mapping method for identifying a broad range of
Externí odkaz:
https://doaj.org/article/537635cc39b84e63886c77d22cdea186
Autor:
Akio Miyakoshi, Hideki Niimi, Tomohiro Ueno, Masahiro Wakasugi, Yoshitsugu Higashi, Yuki Miyajima, Masashi Mori, Homare Tabata, Hiroshi Minami, Akinori Takaoka, Atsushi Hayashi, Yoshihiro Yamamoto, Isao Kitajima
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Sepsis is life-threatening organ dysfunction and is considered a major cause of health loss. However, since the current biomarkers of sepsis reflect the host’s immune response to microorganisms, they would inevitably cause a time-lag. This
Externí odkaz:
https://doaj.org/article/080df6a060674ba4b2287656c06faa19
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective Screening of human and human male DNA is necessary for forensic DNA analyses. Although quantitative real-time PCR (qPCR) is commonly used for detecting and quantifying these DNA targets, its use as a screening tool is time-consumin
Externí odkaz:
https://doaj.org/article/e58f49b4d7894a37858a430e8c936f30
Autor:
Takamasa Nukui, Hideki Niimi, Tomohiro Hayashi, Nobuhiro Dougu, Mamoru Yamamoto, Ryoko Shibuya, Noriyuki Matsuda, Ryo Tanaka, Hiroaki Hirosawa, Risako Furuta, Taichi Mitsui, Hiroki Maesaka, Syuhei Takasawa, Isao Kitajima, Yuji Nakatsuji
Publikováno v:
Neurology Research International, Vol 2024 (2024)
Background. Extracellular adenosine 5′-triphosphate (ATP) acts as a signaling molecule in the peripheral nerves, regulating myelination after nerve injury. The present study examined whether the cerebrospinal fluid (CSF) ATP levels in patients with
Externí odkaz:
https://doaj.org/article/cab707569a3546ecaeffcfa6abae502c
Publikováno v:
International Journal of Infectious Diseases, Vol 125, Iss , Pp 145-148 (2022)
Halomonas hamiltonii is a gram-negative rod bacterium isolated from highly saline environments. H. hamiltonii has rarely been reported as a human pathogen. Herein, we present the first case report of a purulent lymphadenitis caused by H. hamiltonii w
Externí odkaz:
https://doaj.org/article/ba0e43025236433b96151634180ff2b4
Autor:
Yuki Miyajima, Hideki Niimi, Tomohiro Ueno, Atsushi Matsui, Yoshitsugu Higashi, Nozomi Kojima, Mari Kono, Yosuke Iwasaki, Kentaro Nagaoka, Yoshihiro Yamamoto, Isao Kitajima
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundCell population data (CPD) parameters related to neutrophils, such as fluorescent light intensity (NE-SFL) and fluorescent light distribution width index (NE-WY), have emerged as potential biomarkers for sepsis. However, the diagnostic impl
Externí odkaz:
https://doaj.org/article/3322511b88db4d6dbdb257f944772b93
Autor:
Shota Yonezawa, Takayuki Haruki, Keiichi Koizumi, Akinori Taketani, Yusuke Oshima, Makito Oku, Akinori Wada, Tsutomu Sato, Naoki Masuda, Jun Tahara, Noritaka Fujisawa, Shota Koshiyama, Makoto Kadowaki, Isao Kitajima, Shigeru Saito
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1570 (2024)
Multiple myeloma (MM) is a cancer of plasma cells. Normal (NL) cells are considered to pass through a precancerous state, such as monoclonal gammopathy of undetermined significance (MGUS), before transitioning to MM. In the present study, we acquired
Externí odkaz:
https://doaj.org/article/1821c9330e55448ca3919207cb8eb5ea
Publikováno v:
Cells, Vol 12, Iss 18, p 2297 (2023)
Aging is the slowest process in a living organism. During this process, mortality rate increases exponentially due to the accumulation of damage at the cellular level. Cellular senescence is a well-established hallmark of aging, as well as a promisin
Externí odkaz:
https://doaj.org/article/18edddee3a394dd1934ee5c7576d24be
Autor:
Tatsuhiko Ozawa, Hideki Tani, Yuki Anraku, Shunsuke Kita, Emiko Igarashi, Yumiko Saga, Noriko Inasaki, Hitoshi Kawasuji, Hiroshi Yamada, so-Ichiro Sasaki, Mayu Somekawa, Jiei Sasaki, Yoshihiro Hayakawa, Yoshihiro Yamamoto, Yoshitomo Morinaga, Nobuyuki Kurosawa, Masaharu Isobe, Hideo Fukuhara, Katsumi Maenaka, Takao Hashiguchi, Hiroyuki Kishi, Isao Kitajima, Shigeru Saito, Hideki Niimi
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Many potent neutralizing SARS-CoV-2 antibodies have been developed and used for therapies. However, the effectiveness of many antibodies has been reduced against recently emerging SARS-CoV-2 variants, especially the Omicron variant. We identified a h
Externí odkaz:
https://doaj.org/article/8f1dc584acce4456861e83257e43534d
Autor:
Yoji Uejima, Hideki Niimi, Reiko Kato, Mihoko Furuichi, Satoshi Sato, Isao Kitajima, Yutaka Kawano, Tsutomu Oh-Ishi, Hiroshi Kawashima, Eisuke Suganuma
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Spontaneous infection of preexisting solitary renal cysts has been documented in adults but is extremely rare in children. To date, no cases of simple renal cysts infected with Streptococcus pneumoniae have been described. Recentl
Externí odkaz:
https://doaj.org/article/caf0074f15c1481c90567c56a84e25f2