Výsledky vyhledávání - "IRMA H. RUSSO"

Akademický článek

Genomic signature of parity in the breast of premenopausal women

Publikováno v: Breast Cancer Research, Vol 21, Iss 1, Pp 1-19 (2019)

Abstract Background Full-term pregnancy (FTP) at an early age confers long-term protection against breast cancer. Previously, we reported that a FTP imprints a specific gene expression profile in the breast of postmenopausal women. Herein, we evaluat

Externí odkaz: https://doaj.org/article/c2f136d8ce95499fa24fca1f8a2b5501

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Data from Epithelial to Mesenchymal Transition in Human Breast Epithelial Cells Transformed by 17β-Estradiol

Autor: Jose Russo, Thomas R. Sutter, Irma H. Russo, Patricia A. Russo, Shirlean Goodwin, Sandra V. Fernandez, Yong Huang

The estrogen dependence of breast cancer has long been recognized; however, the role of 17β-estradiol (E2) in cancer initiation was not known until we showed that it induces complete neoplastic transformation of the human breast epithelial cells MCF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d24cfcf71c5b92789da93bd50a56cc1
https://doi.org/10.1158/0008-5472.c.6496743

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Genomic signature of parity in the breast of premenopausal women

Publikováno v: Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-19 (2019)

Background Full-term pregnancy (FTP) at an early age confers long-term protection against breast cancer. Previously, we reported that a FTP imprints a specific gene expression profile in the breast of postmenopausal women. Herein, we evaluated gene e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78526ff5c2a172563842b55df6bc844
https://doi.org/10.1186/s13058-019-1128-x

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Oxidized derivative of docosahexaenoic acid preferentially inhibit cell proliferation in triple negative over luminal breast cancer cells

Autor: Michael Slifker, Maria Barton, Irma H. Russo, Andrea Manni, Karam El-Bayoumy, Shantu Amin, Krishne Gowda, Yanrong Su, Thomas J. Pogash, Jose Russo, Julie A. Himmelberger, Ricardo Lopez de Cicco

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 51:121-127

Omega-3 polyunsaturated fatty acids (PUFAs) exert an anticancer effect by affecting multiple cellular mechanisms leading to inhibition of proliferation and induction of apoptosis. It is well known that breast cancer comprises distinct molecular subty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406596e94ac49c332e100808233ee91f
https://doi.org/10.1007/s11626-014-9822-6

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Mimicking pregnancy as a strategy for breast cancer prevention

Autor: Christina George, Lucas Tadeu Bidinotto, David Armiss, Julia Santucci-Pereira, Ricardo Lopez de Cicco, Fathima Sheriff, Irma H. Russo, Patricia A. Russo, Yanrong Su, Jose Russo, Johana E. Vanegas

Publikováno v: Breast Cancer Management. 2:283-294

SUMMARY Pregnancy and its effects on breast cancer risk have been widely investigated; there is consensus among researchers that early pregnancy confers protection against breast cancer later in life, whereas nulliparity and late-age parity have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882824d64faaa4f8089e5b967c213064
https://doi.org/10.2217/bmt.13.16

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Progressive increase of glucose transporter-3 (GLUT-3) expression in estrogen-induced breast carcinogenesis

Autor: Johana E. Vanegas, Mehmet Ali Kocdor, Irma H. Russo, Julia S. Pereira, Jose Russo, Hilal Kocdor

Publikováno v: Clinical and Translational Oncology. 15:55-64

Increased glucose uptake and glycolysis are main metabolic characteristics of malignant cells. A family of glucose transporters (GLUTs) facilitates glucose movement across the plasma membranes in a tumor-specific manner. Glucose transporter-1 (GLUT-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3a0238068bf06f65dcd2ae13c3146c
https://doi.org/10.1007/s12094-012-0882-3

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Molecular basis of pregnancy-induced breast cancer prevention

Autor: Irma H. Russo, Jose Russo

Publikováno v: Hormone Molecular Biology and Clinical Investigation. 9:3-10

Reduction in breast cancer risk is associated with elevated circulating levels of human chorionic gonadotropin (hCG) during the first trimester of gestation. The knowledge that hCG also modifies the genomic signature of breast epithelial cells, from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501536bc82b65171ffdbe21b69a78d87
https://doi.org/10.1515/hmbci-2011-0136

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