Zobrazeno 1 - 10
of 19
pro vyhledávání: '"IRI, ischemia reperfusion injury"'
Autor:
Ingo Hilgendorf, Filip K. Swirski, Amit Kalgukar, Leonard Buckbinder, Roger B. Ruggeri, Stefan Schob, John W. Chen, Matthew Sebas, Benoit Tricot, Yoshiko Iwamoto, Christian Cortes, Benjamin Pulli, Gabriel Courties, Anping Dong, Wei Zheng, Athanasia Skoura, Muhammad Ali, Matthias Nahrendorf
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 633-643 (2016)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • The inflammatory enzyme MPO is a potential therapeutic target in cardiovascular diseases. • PF-1355 is an orally bioavailable mechanism-based inhibitor of MPO enzymatic activity. PF-1355 treatment successfully in
Highlights • The inflammatory enzyme MPO is a potential therapeutic target in cardiovascular diseases. • PF-1355 is an orally bioavailable mechanism-based inhibitor of MPO enzymatic activity. PF-1355 treatment successfully in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f865d2b9a48e7c50f62499fffc36ea2c
https://doi.org/10.1016/j.jacbts.2016.09.004
https://doi.org/10.1016/j.jacbts.2016.09.004
Autor:
Mollereau, B., Rzechorzek, N. M., Roussel, B. D., Sedru, M., Brink, D., Bailly-Maitre, B., Palladino, F., Medinas, D. B., Domingos, P. M., Hunot, S., Chandran, S., Birman, S., Baron, T., Vivien, D., Duarte, C. B., Ryoo, H. D., Steller, H., Urano, F., Chevet, E., Kroemer, G., Ciechanover, A., Calabrese, E. J., Kaufman, R. J., Hetz, C
Publikováno v:
Brain Research
Brain Research, Elsevier, 2016, 1648 (B), pp.603-616. 〈10.1016/j.brainres.2016.02.033〉
Brain Research, Elsevier, 2016, 1648 (B), pp.603-616. ⟨10.1016/j.brainres.2016.02.033⟩
Mollereau, B, Rzechorzek, N M, Roussel, BD, Sedru, M, Van denBrink, D, Bailly-Maitre, B, Palladino, F, Medinas, DB, Domingos, PM, Hunot, S, Chandran, S, Birman, S, Baron, T, Vivien, D, Duarte, CB, Ryoo, HD, Steller, H, Urano, F, Chevet, E, Kroemer, G, Ciechanover, A, Calabrese, EJ, Kaufman, RJ & Hetz, C 2016, ' Adaptive preconditioning in neurological diseases- therapeutic insights from proteostatic perturbations ', Brain Research . https://doi.org/10.1016/j.brainres.2016.02.033
Brain Research, Elsevier, 2016, 1648 (B), pp.603-616. 〈10.1016/j.brainres.2016.02.033〉
Brain Research, Elsevier, 2016, 1648 (B), pp.603-616. ⟨10.1016/j.brainres.2016.02.033⟩
Mollereau, B, Rzechorzek, N M, Roussel, BD, Sedru, M, Van denBrink, D, Bailly-Maitre, B, Palladino, F, Medinas, DB, Domingos, PM, Hunot, S, Chandran, S, Birman, S, Baron, T, Vivien, D, Duarte, CB, Ryoo, HD, Steller, H, Urano, F, Chevet, E, Kroemer, G, Ciechanover, A, Calabrese, EJ, Kaufman, RJ & Hetz, C 2016, ' Adaptive preconditioning in neurological diseases- therapeutic insights from proteostatic perturbations ', Brain Research . https://doi.org/10.1016/j.brainres.2016.02.033
In neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ac2c955da4a10f0f472d98f9cd8189b5
http://europepmc.org/articles/PMC5010532
http://europepmc.org/articles/PMC5010532
Autor:
Kasper Jarlhelt Andersen, Anders Riegels Knudsen, Jens R. Nyengaard, Pia Svendsen, Jonas Heilskov Graversen, Søren K. Moestrup, Frank Viborg Mortensen, Stephen Hamilton-Dutoit, Lin Nanna Okholm Møller, Holger Jon Møller, Elise Marie Okholm Møller
Publikováno v:
Møller, L N O, Knudsen, A R, Andersen, K J, Nyengaard, J R, Hamilton-Dutoit, S, Okholm Møller, E M, Svendsen, P, Møller, H J, Moestrup, S K, Graversen, J H & Mortensen, F V 2015, ' Anti-CD163-dexamethasone protects against apoptosis after ischemia/reperfusion injuries in the rat liver ', Annals of Medicine and Surgery, vol. 4, no. 4, 130, pp. 331-337 . https://doi.org/10.1016/j.amsu.2015.09.001
Annals of Medicine and Surgery
Møller, L N O, Knudsen, A R, Andersen, K J, Nyengaard, J R, Hamilton-Dutoit, S, Okholm Møller, E M, Svendsen, P, Møller, H J, Moestrup, S K, Graversen, J H & Mortensen, F V 2015, ' Anti-CD163-dexamethasone protects against apoptosis after ischemia/reperfusion injuries in the rat liver ', Annals of Medicine and Surgery, vol. 4, no. 4, pp. 331-337 . https://doi.org/10.1016/j.amsu.2015.09.001
Annals of Medicine and Surgery
Møller, L N O, Knudsen, A R, Andersen, K J, Nyengaard, J R, Hamilton-Dutoit, S, Okholm Møller, E M, Svendsen, P, Møller, H J, Moestrup, S K, Graversen, J H & Mortensen, F V 2015, ' Anti-CD163-dexamethasone protects against apoptosis after ischemia/reperfusion injuries in the rat liver ', Annals of Medicine and Surgery, vol. 4, no. 4, pp. 331-337 . https://doi.org/10.1016/j.amsu.2015.09.001
Aim The Pringle maneuver is a way to reduce blood loss during liver surgery. However, this may result in ischemia/reperfusion injury in the development of which Kupffer cells play a central role. Corticosteroids are known to have anti-inflammatory ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2152cd2f1e7a50822acf0aa490951115
https://doi.org/10.1016/j.amsu.2015.09.001
https://doi.org/10.1016/j.amsu.2015.09.001
Publikováno v:
EBioMedicine
EBioMedicine, Vol 28, Iss C, Pp 31-42 (2018)
EBioMedicine, Vol 28, Iss C, Pp 31-42 (2018)
Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific inflammatory responses that can result in the loss of kidney graft viability. However, the long-term consequence of IRI on renal grafts survival is uncertain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdc33b0ef540529ecdfee81e65bf0c7
http://hdl.handle.net/10044/1/56746
http://hdl.handle.net/10044/1/56746
Publikováno v:
Transplant Immunology
Introduction IRI results from the interruption then reinstatement of an organ's blood supply, and this poses a significant problem in liver transplantation and resectional surgery. In this paper, we explore the role T cells play in the pathogenesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1be54b928882c537fef5b63aa80fee1a
https://pubmed.ncbi.nlm.nih.gov/28797737
https://pubmed.ncbi.nlm.nih.gov/28797737
Publikováno v:
Pharmacology & Therapeutics
Ischemic heart disease (IHD) is the leading cause of death and disability worldwide. Therefore, novel therapeutic targets for protecting the heart against acute ischemia/reperfusion injury (IRI) are required to attenuate cardiomyocyte death, preserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbe960ba7dcb993a0bd37b3cf0b860cb
https://pubmed.ncbi.nlm.nih.gov/26481155
https://pubmed.ncbi.nlm.nih.gov/26481155
Akademický článek
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Autor:
Ali RAH; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq., Altimimi M; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq., Hadi NR; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq.
Publikováno v:
Journal of medicine and life [J Med Life] 2023 Aug; Vol. 16 (8), pp. 1274-1281.
Autor:
Yahiya YI; Department of Pharmacology, Faculty of Pharmacy, University of Alkafeel, Najaf, Iraq., Hadi NR; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq., Abu Raghif A; Deptartment of Pharmacology, College of Medicine, Al Nahrain University, Baghdad, Iraq., Al Habooby NGS; Medical College, University of Kufa, Kufa, Iraq.
Publikováno v:
Journal of medicine and life [J Med Life] 2023 Apr; Vol. 16 (4), pp. 623-630.
Autor:
Banker A; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Bhatt N; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Rao PS; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Agrawal P; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Shah M; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Nayak M; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India., Mohanka R; Department of Liver Transplant and HPB Surgery, Sir HN Reliance Foundation Hospital, Mumbai, India.
Publikováno v:
Journal of clinical and experimental hepatology [J Clin Exp Hepatol] 2023 Mar-Apr; Vol. 13 (2), pp. 335-349. Date of Electronic Publication: 2022 Aug 10.