Zobrazeno 1 - 10
of 1 987
pro vyhledávání: '"IRF1"'
Autor:
Aiyuan Zhou, Xiyan Zhang, Xinyue Hu, Tiao Li, Wenzhong Peng, Hang Yang, Dingding Deng, Chunheng Mo, Rongli Lu, Pinhua Pan
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Interferon regulatory factor-1 (IRF1) is a transcription factor that plays a significant role in various biological processes, including inflammatory injury, viral infection, cell death, and immune responses, and it has been exten
Externí odkaz:
https://doaj.org/article/2d08207743c6431082520b192b22ec89
Autor:
Jae Yeon Choi, Hyun Jeong Seok, Dong Hyeon Lee, Junhye Kwon, Ui Sup Shin, Incheol Shin, In Hwa Bae
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Although the representative treatment for colorectal cancer (CRC) is radiotherapy, cancer cells survive due to inherent radioresistance or resistance acquired after radiation treatment, accelerating tumor malignancy and causing lo
Externí odkaz:
https://doaj.org/article/dced9a6da5544a69bfd1fce331e77708
Autor:
Xin Wang, Yangyang Chai, Yuan Quan, Jiaming Wang, Jiaying Song, Wenkai Zhou, Xiaoqing Xu, Henan Xu, Bingjing Wang, Xuetao Cao
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Background Tumor cells develop multiple mechanisms to facilitate their immune evasion. Identifying tumor-intrinsic factors that support immune evasion may provide new strategies for cancer immunotherapy. We aimed to explore the function and
Externí odkaz:
https://doaj.org/article/6cbeea5f9f4248639b02dae127ba0c36
Autor:
Lucia Martinkova, Pavlina Zatloukalova, Martina Kucerikova, Nela Friedlova, Zuzana Tylichova, Filip Zavadil-Kokas, Ted Robert Hupp, Philip John Coates, Borivoj Vojtesek
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-21 (2024)
Abstract Background PD-L1 expression on cancer cells is an important mechanism of tumor immune escape, and immunotherapy targeting the PD-L1/PD1 interaction is a common treatment option for patients with melanoma. However, many patients do not respon
Externí odkaz:
https://doaj.org/article/dd7c42a1c1ae4a469881435e5bda7846
Autor:
Kai Sun, Fan Lu, Liangcai Hou, Xiong Zhang, Chunran Pan, Haigang Liu, Zehang Zheng, Zhou Guo, Zhaoxuan Ruan, Yanjun Hou, Jinming Zhang, Fengjing Guo, Wentao Zhu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Z-DNA binding protein 1 (ZBP1) is a nucleic acid sensor that is involved in multiple inflammatory diseases, but whether and how it contributes to osteoarthritis (OA) are unclear. Methods Cartilage tissues were harvested from patie
Externí odkaz:
https://doaj.org/article/0af38da6199346bfb3e04df823d61627
Autor:
Chunhui Zhong, Gaoli She, Yukun Zhao, Yufang Liu, Jingmin Li, Xiaona Wei, Zexin Chen, Keyu Zhao, Zhiqing Zhao, Zhichao Xu, Hao Zhang, Yongchang Cao, Chunyi Xue
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-14 (2024)
Abstract Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine enteric coronavirus that causes acute watery diarrhea, vomiting, and dehydration in newborn piglets. The type III interferon (IFN-λ) response serves as the primary defe
Externí odkaz:
https://doaj.org/article/bb5c6f8808e441c3945e6275af16d634
Akademický článek
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Autor:
Shahenaz S. Salih, MSc, Mohammed S. Abdelaziz, Ph.D, Ibtehal M. Abdelhag, MSc, Altaf S. Mosad, MSc
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 1, Pp 99-105 (2024)
الملخص: أهداف البحث: تهدف هذه الدراسة إلى الكشف عن تعبير بروتين ليجند 1 المبرمج للموت في أنسجة سرطان الثدي، مرتبطة بتعبيرات متنوعة لحالة ا
Externí odkaz:
https://doaj.org/article/99616f22a2bd4927bcc51ba9f800e5dd
Autor:
Hao Tang, Xiaoshan Gong, Jingjin Dai, Jun Gu, Zicai Dong, Yuan Xu, Zhaoyang Hu, Chunrong Zhao, Jiezhong Deng, Shiwu Dong
Publikováno v:
Journal of Orthopaedic Translation, Vol 44, Iss , Pp 47-59 (2024)
Background: Osteoarthritis (OA) is a chronic degenerative joint disease that primarily affects middle-aged and elderly individuals. The decline in chondrocyte function plays a crucial role in the development of OA. Inflammasome-mediated chondrocyte p
Externí odkaz:
https://doaj.org/article/d9fe5c050e8a4cccbebf005ff9755708
Autor:
Jie Yuan, Minxia Lin, Shaohua Yang, Hao Yin, Shaoyong Ouyang, Hong Xie, Hongmei Tang, Xiaowei Ou, Zhiqiang Zeng
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31137- (2024)
Background: The prevalence of breast cancer (BRCA), which is common among women, is on the rise. This study applied network pharmacology to explore the potential mechanism of action of herba sarcandrae in BRCA and construct a prognostic signature com
Externí odkaz:
https://doaj.org/article/e31808e0a2304264abc00cde84d7fdf8