Zobrazeno 1 - 10
of 161
pro vyhledávání: '"IPMK"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1390 (2024)
Non-alcoholic steatohepatitis (NASH) is an inflammatory form of non-alcoholic fatty liver disease (NAFLD), closely associated with disease progression, cirrhosis, liver failure, and hepatocellular carcinoma. Time-restricted feeding (TRF) has been sho
Externí odkaz:
https://doaj.org/article/29347079c5914612951e8474885b6fbd
Autor:
Nebojša Pavlović, Nastasija Milošević Sopta, Darko Mitrović, Dragana Zaklan, Ana Tomas Petrović, Nebojša Stilinović, Saša Vukmirović
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 192 (2023)
Despite its beneficial pharmacological effects in the brain, partly by modulating inositol phosphate multikinase (IPMK) activity, the therapeutic use of quercetin is limited due to its poor solubility, low oral bioavailability, and low permeability t
Externí odkaz:
https://doaj.org/article/52af7076973046fbb5a71f3705a03409
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1509 (2023)
Metazoan cell nuclei contain non-membrane pools of the phosphoinositide lipid PI(4,5)P2 (PIP2), but how this hydrophobic lipid exists within the aqueous nucleoplasm remains unclear. Steroidogenic Factor-1 (NR5A1, SF-1) is a nuclear receptor that bind
Externí odkaz:
https://doaj.org/article/17725859099f48649a1aee5200fbffbb
Autor:
Seung Eun Park, Dongeun Lee, Jae Woong Jeong, Su-Hyung Lee, Seung Ju Park, Jaeseung Ryu, Se Kyu Oh, Hanseul Yang, Sungsoon Fang, Seyun Kim
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 6, Pp 1235-1256 (2022)
Background & Aims: Inositol polyphosphate multikinase (IPMK), an essential enzyme for inositol phosphate metabolism, has been known to mediate major biological events such as growth. Recent studies have identified single-nucleotide polymorphisms in t
Externí odkaz:
https://doaj.org/article/be5800e75f4f485a8e6f418cc94060e3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hyoungjoon Ahn, Jong Seong Roh, Seulgi Lee, Jiyoon Beon, Beomgu Lee, Dong Hyun Sohn, Seyun Kim
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 4, Pp 219-226 (2021)
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by widespread joint inflammation, which leads to joint damage, disability, and mortality. Among the several types of immune cells, myeloid cells such as macrophages are critical
Externí odkaz:
https://doaj.org/article/c30870262074448d99494e3cc32b421f
Autor:
Jiyoon Beon, Sungwook Han, Hyeokjun Yang, Seung Eun Park, Kwangbeom Hyun, Song-Yi Lee, Hyun-Woo Rhee, Jeong Kon Seo, Jaehoon Kim, Seyun Kim, Daeyoup Lee
Publikováno v:
eLife, Vol 11 (2022)
Inositol polyphosphate multikinase (IPMK), a key enzyme in inositol polyphosphate (IP) metabolism, is a pleiotropic signaling factor involved in major biological events, including transcriptional control. In the yeast, IPMK and its IP products promot
Externí odkaz:
https://doaj.org/article/2ce034c9c55349b08cbd3576144b199c
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 332 (2023)
Inositol polyphosphate multikinase (IPMK) is a pleiotropic enzyme responsible for the production of inositol polyphosphates and phosphoinositide. IPMK in macrophages was identified as a key factor for the full activation of the Toll-like receptor 4 (
Externí odkaz:
https://doaj.org/article/68a08b3b00da43b5a5b2dfabc04c9843
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-4 (2019)
Abstract Inositol polyphosphate multikinase (IPMK), the key enzyme responsible for the synthesis of higher inositol polyphosphates and phosphatidylinositol 3, 4, 5-trisphosphate, is known to mediate various biological events, such as cellular growth
Externí odkaz:
https://doaj.org/article/d335270426634beabc64050aedda7318