Transfer Learning for Structural Health Monitoring in Bridges That Underwent Retrofitting

Autor: Marcus Omori Yano, Eloi Figueiredo, Samuel da Silva, Alexandre Cury, Ionut Moldovan

Publikováno v: Buildings, Vol 13, Iss 9, p 2323 (2023)

Bridges are built to last more than 100 years, spanning many human generations. Throughout their lifetime, their service requirements may change, or they age and often suffer a material degradation process that can lead to the need of retrofitting. I

Externí odkaz: https://doaj.org/article/33648137a4c04d02a81d2756220d4176

Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment.

Autor: Sabine Seeler, Liviu-Ionut Moldovan, Trine Bertelsen, Henrik Hager, Lars Iversen, Claus Johansen, Jørgen Kjems, Lasse Sommer Kristensen

Publikováno v: PLoS ONE, Vol 17, Iss 9, p e0275219 (2022)

Psoriasis is a common chronic inflammatory skin disease accompanied by heterogenous clinical and histological features, including a characteristic keratinocyte hyperproliferation and dermal immunogenic profile. In addition, psoriasis is associated wi

Externí odkaz: https://doaj.org/article/8509030fd17848ec958f7cae86d00585

The HSP90 inhibitor RGRN‐305 exhibits strong immunomodulatory effects in human keratinocytes

Autor: Gautam S. Ghatnekar, Liviu Ionut Moldovan, Rikke S Hansen, Anne Bregnhøj, Christina L. Grek, Claus Johansen, Lars Iversen, Katrine K H Thuesen, Lasse Sommer Kristensen

Publikováno v: Hansen, R S, Thuesen, K K, Bregnhøj, A, Moldovan, L I, Kristensen, L S, Grek, C L, Ghatnekar, G S, Iversen, L & Johansen, C 2021, ' The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes ', Experimental Dermatology, vol. 30, no. 6, pp. 773-781 . https://doi.org/10.1111/exd.14302

Keratinocytes are the key cellular target for IL-17A-mediated effects in psoriasis and HSP90 is important for IL-17A-mediated signalling. RGRN-305 is a novel HSP90 inhibitor reported to reduce psoriatic phenotypes in preclinical animal models. The ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b241235324b480ecc2d1377251fda6c2
https://doi.org/10.1111/exd.14302

Reliability of probabilistic numerical data for training machine learning algorithms to detect damage in bridges

Autor: Mihai Adrian Bud, Ionut Moldovan, Lucian Radu, Mihai Nedelcu, Eloi Figueiredo

Publikováno v: Structural Control and Health Monitoring. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06f6ba7c7a6991046ca5cb3a98a711f9
https://doi.org/10.1002/stc.2950

Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles

Autor: Uppala Ranjitha, Liviu Ionut Moldovan, Johann E. Gudjonsson, Stephen Weidinger, Jørgen Kjems, Lam C. Tsoi, Lasse Sommer Kristensen, Henrik Hager

Publikováno v: Moldovan, L I, Tsoi, L C, Ranjitha, U, Hager, H, Weidinger, S, Gudjonsson, J E, Kjems, J & Kristensen, L S 2021, ' Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles ', Experimental Dermatology, vol. 30, no. 8, pp. 1187-1196 . https://doi.org/10.1111/exd.14227
Moldovan, L I, Tsoi, L C, Ranjitha, U, Hager, H, Weidinger, S, Gudjonsson, J E, Kjems, J & Kristensen, L S 2021, ' Characterization of circular RNA transcriptomes in psoriasis and atopic dermatitis reveals disease-specific expression profiles ', Experimental Dermatology, vol. 30, no. 8, pp. 1187-1196 . https://doi.org/10.1111/exd.14227
Experimental Dermatology

Atopic dermatitis (AD) and psoriasis are two common chronic inflammatory skin diseases that are associated with various comorbidities. Circular RNA (circRNA) constitutes a major class of non-coding RNAs that have been implicated in many human disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5d1821dd207a12bce3ca064baeb43a
https://pure.au.dk/portal/da/publications/characterization-of-circular-rna-transcriptomes-in-psoriasis-and-atopic-dermatitis-reveals-diseasespecific-expression-profiles(13c40bcb-c847-4007-9712-d2c80b0c64fb).html