Zobrazeno 1 - 10
of 55
pro vyhledávání: '"INTESTINAL-CELL KINASE"'
Akademický článek
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Publikováno v:
Cells, Vol 8, Iss 7, p 677 (2019)
Loss-of-function mutations in the human ICK (intestinal cell kinase) gene cause dysfunctional primary cilia and perinatal lethality which are associated with human ciliopathies. The enzyme that we herein call CAPK (ciliopathy-associated protein kinas
Externí odkaz:
https://doaj.org/article/05257fa35ace42dcb700b76483f1cf26
Autor:
Yang, Ying, Paivinen, Pekka, Xie, Chang, Krup, Alexis Leigh, Makela, Tomi P., Mostov, Keith E., Reiter, Jeremy F.
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
How tubular organs elongate is poorly understood. We found that attenuated ciliary Hedgehog signaling in the gut wall impaired patterning of the circumferential smooth muscle and inhibited proliferation and elongation of developing intestine and esop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597dcf28dbf1e021b9f18361cc110694
https://doi.org/10.1038/s41467-021-27319-z
https://doi.org/10.1038/s41467-021-27319-z
Autor:
Bohumil Fafilek, Peter Konik, Iva Gudernova, Jennifer Zieba, Miroslav Varecha, Sara P. Abraham, Tomas Gregor, Ivan Duran, David Šmajs, Gert Jansen, Marketa Tomanova, Pavel Krejci, So Hyun Park, Jieun Song, Tomáš Bárta, Deborah Krakow, Lukas Balek, Alexandru Nita, David Potesil, Zheng Fu, Neha Basheer, Hyuk Wan Ko, Aleš Hampl, Michaela Bosakova, Jana Kučerová, Juraj Bosák, Lukáš Trantírek, Zbynek Zdrahal
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the U.S.A., 116(10), 4316-4325. National Academy of Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 116(10), 4316-4325. National Academy of Sciences
Significance A properly functioning primary cilium is prerequisite for both normal development and aging of all ciliated organisms, including humans. In vertebrates, the signaling of Hedgehog family morphogens depends entirely on primary cilium. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837d1a7db436aa04d141b528ac31c912
http://europepmc.org/articles/PMC6410813
http://europepmc.org/articles/PMC6410813
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Juvenile myoclonic epilepsy (JME), a lifelong disorder that starts during adolescence, is the most common of genetic generalized epilepsy syndromes. JME is characterized by awakening myoclonic jerks and myoclonic-tonic-clonic (m-t-c) grand mal convul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c75f416efdd933a49518d4c10ab995
https://doi.org/10.3389/fncel.2019.00433
https://doi.org/10.3389/fncel.2019.00433
Publikováno v:
Frontiers in Cellular Neuroscience. 13
Juvenile myoclonic epilepsy (JME), a lifelong disorder that starts during adolescence, is the most common of genetic generalized epilepsy syndromes. JME is characterized by awakening myoclonic jerks and myoclonic-tonic-clonic (m-t-c) grand mal convul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________83::8522a8d2a4bc7c14b5e140ebfeaec8a5
https://cris.maastrichtuniversity.nl/en/publications/60b210c5-958c-4e61-ad0c-2269b653e0e3
https://cris.maastrichtuniversity.nl/en/publications/60b210c5-958c-4e61-ad0c-2269b653e0e3
Publikováno v:
Cells
Volume 8
Issue 7
Cells, Vol 8, Iss 7, p 677 (2019)
Volume 8
Issue 7
Cells, Vol 8, Iss 7, p 677 (2019)
Loss-of-function mutations in the human ICK (intestinal cell kinase) gene cause dysfunctional primary cilia and perinatal lethality which are associated with human ciliopathies. The enzyme that we herein call CAPK (ciliopathy-associated protein kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4327958071b2030f942530bf7491a3bb
Autor:
Josemir Sander, Patrick May, Rudi Balling, Eduardo Pérez-Palma, Karl Martin Klein, Ingrid Scheffer, Andreja Avbersek, Dheeraj Bobbili, Samuel Berkovic, Costin Leu, Rhys Thomas, Anthony Marson, Henrike Heyne, Janine Altmüller, Sarah Weckhuysen, Michael Nothnagel, Terence O'Brien, Martin Krenn, Aarno Palotie, Mahmoud Koko, Seo-Kyung Chung, Graeme Sills, Stefan Wolking, Antonio Gambardella, Gianpiero Cavalleri
Publikováno v:
The New England journal of medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80740b07f1d3420634dcec3ebeca86a6
https://pubmed.ncbi.nlm.nih.gov/29539279
https://pubmed.ncbi.nlm.nih.gov/29539279