Zobrazeno 1 - 10
of 1 061
pro vyhledávání: '"INTERCALATED DISC"'
Autor:
Adams, William Patrick
Sudden cardiac death is largely attributable to sudden onset ventricular arrhythmias. Alterations in cardiac conduction, particularly the slowing of conduction velocity is one major factor in arrhythmogenesis. By understanding the mechanisms and fact
Externí odkaz:
https://hdl.handle.net/10919/119281
Autor:
Giuseppina Mastrototaro, Pierluigi Carullo, Jianlin Zhang, Beatrice Scellini, Nicoletta Piroddi, Simona Nemska, Maria Carmela Filomena, Simone Serio, Carol A Otey, Chiara Tesi, Fabian Emrich, Wolfgang A Linke, Corrado Poggesi, Simona Boncompagni, Marie-Louise Bang
Publikováno v:
eLife, Vol 12 (2023)
Palladin (PALLD) belongs to the PALLD/myopalladin (MYPN)/myotilin family of actin-associated immunoglobulin-containing proteins in the sarcomeric Z-line. PALLD is ubiquitously expressed in several isoforms, and its longest 200 kDa isoform, predominan
Externí odkaz:
https://doaj.org/article/48822b874b00423185ecb43b08a61552
Autor:
Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here
Externí odkaz:
https://doaj.org/article/cc6a0c4d5c4f4d3485748c72de4d581d
Autor:
Willem B. van Ham, Esmeralda E. M. Meijboom, Merel L. Ligtermoet, Peter G. J. Nikkels, Toon A. B. van Veen
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 8, p 354 (2023)
The development of the normal human heart, ranging from gestational age to the mature adult heart, relies on a very delicate and timely orchestrated order of processes. One of the most striking alterations in time is the gradual extinction of the abi
Externí odkaz:
https://doaj.org/article/54e18138646b4512814ae4be390912db
Publikováno v:
Applied Microscopy, Vol 50, Iss 1, Pp 1-9 (2020)
Abstract Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates. Nevertheless, certain arthropods a
Externí odkaz:
https://doaj.org/article/f564d2a205824ab9bf28a3b39b5464b3
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Electrical conduction in cardiac ventricular tissue is regulated via sodium (Na+) channels and gap junctions (GJs). We and others have recently shown that Na+channels preferentially localize at the site of cell-cell junctions, the intercalated disc (
Externí odkaz:
https://doaj.org/article/e2b6d5a06aa042f18d7e7d9758a7bdf8
Autor:
Tyler L. Stevens, Heather R. Manring, Michael J. Wallace, Aaron Argall, Trevor Dew, Peter Papaioannou, Steve Antwi-Boasiako, Xianyao Xu, Stuart G. Campbell, Fadi G. Akar, Maegen A. Borzok, Thomas J. Hund, Peter J. Mohler, Sara N. Koenig, Mona El Refaey
Publikováno v:
Cells, Vol 11, Iss 19, p 3049 (2022)
Arrhythmogenic cardiomyopathy (ACM) is an inherited disorder characterized by fibro-fatty infiltration with an increased propensity for ventricular arrhythmias and sudden death. Genetic variants in desmosomal genes are associated with ACM. Incomplete
Externí odkaz:
https://doaj.org/article/63890685f8b04fc6b2be5d434329bc0f
Autor:
Yonghe Ding, Jingchun Yang, Peng Chen, Tong Lu, Kunli Jiao, David J. Tester, John R. Giudicessi, Kai Jiang, Michael J. Ackerman, Yigang Li, Dao Wu Wang, HoN‐chi Lee, Dao Wen Wang, Xiaolei Xu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)
Background Sorbs2b (sorbin and SH3 domain‐containing 2b) was recently identified as a cardiomyopathy gene from a zebrafish mutagenesis screen. However, cardiac functions of its mammalian ortholog remain elusive. Methods and Results We conducted a d
Externí odkaz:
https://doaj.org/article/af816d412d974fd3a6b29b8743241fc1
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/584c1491620940ac8bac1ad618301271