In sickness and in health : The functional role of extracellular vesicles in physiology and pathology in vivo Part II: Pathology

Autor: Yates, Abi G., Pink, Ryan C., Erdbrugger, Uta, Siljander, Pia R-M., Dellar, Elizabeth R., Pantazi, Paschalia, Akbar, Naveed, Cooke, William R., Vatish, Manu, Dias-Neto, Emmanuel, Anthony, Daniel C., Couch, Yvonne

It is clear from Part I of this series that extracellular vesicles (EVs) play a critical role in maintaining the homeostasis of most, if not all, normal physiological systems. However, the majority of our knowledge about EV signalling has come from s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1593::c99fd543d86ddf74f5e4101aac1c6aeb
http://hdl.handle.net/10138/341828

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Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic beta Cell Death and May Contribute to Type 1 Diabetes Development

Autor: Sophie Rome, Karim Bouzakri, Francesca Mancarella, Francesco Dotta, Bryan J. González, Christian Boitard, Romano Regazzi, Niels L. Mulder, Véronique Menoud, Alena Donda, Janine K. Kruit, Camilla Jandus, Angelika Jurdzinski, Pedro Romero, Guido Sebastiani, Claudiane Guay, Michel Pinget

Publikováno v: Cell Metab
Cell Metab, 2018
Cell Metabolism
Cell Metabolism, Elsevier, 2019, 29 (2), pp.348-361. ⟨10.1016/j.cmet.2018.09.011⟩
Cell Metabolism, 2019, 29 (2), pp.348-361. ⟨10.1016/j.cmet.2018.09.011⟩
Cell Mol Immunol
Cell metabolism, 29(2), 348-+. CELL PRESS
Cell metabolism, vol. 29, no. 2, pp. 348-361.e6
Cell Metabolism, Vol. 29, No 2 (2019) pp. 348-361.e6

International audience; Type 1 diabetes is an autoimmune disease initiated by the invasion of pancreatic islets by immune cells that selectively kill the beta cells. We found that rodent and human T lymphocytes release exosomes containing the microRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f878c654b1d2d4d0be201a71ca77ec53
https://hal.archives-ouvertes.fr/hal-02003439

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