Zobrazeno 1 - 10
of 3 821
pro vyhledávání: '"INDUCED CELL-DEATH"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Gastric cancer (GC) is the third leading cause of cancer-related deaths globally. Despite advancements in treatment, the overall 5-year survival rate remains below 30%, particularly in advanced stages. Copper metabolism, vital for
Externí odkaz:
https://doaj.org/article/b2b0e146d2644348aa2cd245e0391117
Autor:
Zhongwen Zhang, Haolong Zhang, Zheng Zhang, Doblin Sandai, Ping Lu, Haoling Zhang, Jianjun Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCell death mechanisms are integral to the pathogenesis of breast cancer (BC), with ATP-induced cell death (AICD) attracting increasing attention due to its distinctive specificity and potential therapeutic applications.MethodsThis study emp
Externí odkaz:
https://doaj.org/article/5972129484f845f9905190fd30e36b25
Publikováno v:
Cells, Vol 13, Iss 22, p 1825 (2024)
Acid-induced ion flux plays a role in pathologies where tissue acidification is prevalent, including cancer. In 2019, TMEM206 was identified as the molecular component of acid-induced chloride flux. Localizing to the plasma membrane, TMEM206 contribu
Externí odkaz:
https://doaj.org/article/a4969146136a4942984637a906f0493c
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Intra-tumoral heterogeneity (ITH) is a distinguished hallmark of cancer, and cancer stem cells (CSCs) contribute to this malignant characteristic. Therefore, it is of great significance to investigate and even target the regulator
Externí odkaz:
https://doaj.org/article/62d92eb037ea488b89deee11c0bd102a
Autor:
Xavier Martiáñez-Vendrell, Jonna Bloeme-ter Horst, Roy Hutchinson, Coralie Guy, Andrew G. Bowie, Marjolein Kikkert
Publikováno v:
Viruses, Vol 16, Iss 6, p 898 (2024)
Human coronavirus 229E (HCoV-229E) is associated with upper respiratory tract infections and generally causes mild respiratory symptoms. HCoV-229E infection can cause cell death, but the molecular pathways that lead to virus-induced cell death as wel
Externí odkaz:
https://doaj.org/article/8cd642843f9f48f68bae503d48bf3132
Autor:
Wei Wang, Haolong Zhang, Doblin Sandai, Rui Zhao, Jinxia Bai, Yanfei Wang, Yong Wang, Zhongwen Zhang, Hao-Ling Zhang, Zhi-Jing Song
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
ATP-induced cell death has emerged as a captivating realm of inquiry with profound ramifications in the context of osteoporosis. This study unveils a paradigm-shifting hypothesis that illuminates the prospective involvement of ATP-induced cellular de
Externí odkaz:
https://doaj.org/article/48003c156de64f598445aa3b61332384
Autor:
Aimin Jiang, Peng Luo, Ming Chen, Yu Fang, Bing Liu, Zhenjie Wu, Le Qu, Anbang Wang, Linhui Wang, Chen Cai
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-27 (2022)
Abstract Rationale Recent research has indicated that cuprotosis, or copper induced cell death, is a novel type of cell death that could be utilized as a new weapon for cancer management. However, the characteristics and implications of such signatur
Externí odkaz:
https://doaj.org/article/43342f22c5564682b89e8a22852dff30
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Suresh Velnati, Sara Centonze, Giulia Rossino, Beatrice Purghè, Annamaria Antona, Luisa Racca, Sabrina Mula, Elisa Ruffo, Valeria Malacarne, Mario Malerba, Marcello Manfredi, Andrea Graziani, Gianluca Baldanzi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPhosphorylation of diacylglycerol by diacylglycerol-kinases represents a major inhibitory event constraining T cell activation upon antigen engagement. Efficient TCR signalling requires the inhibition of the alpha isoform of diacylglycerol
Externí odkaz:
https://doaj.org/article/d7c6301456144c649c298c8248baa1ae