Zobrazeno 1 - 10
of 8 528
pro vyhledávání: '"IMMEDIATE-EARLY GENE"'
Publikováno v:
eLife, Vol 12 (2024)
Monitoring neuronal activity at single-cell resolution in freely moving Drosophila engaged in social behaviors is challenging because of their small size and lack of transparency. Extant methods, such as Flyception, are highly invasive. Whole-brain c
Externí odkaz:
https://doaj.org/article/dbb98fedca7d40399ad6b824be190de6
Autor:
Isaac Vingan, Shwetha Phatarpekar, Victoria Sook Keng Tung, Alejandro Iván Hernández, Oleg V. Evgrafov, Juan Marcos Alarcon
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The rodent hippocampus is a spatially organized neuronal network that supports the formation of spatial and episodic memories. We conducted bulk RNA sequencing and spatial transcriptomics experiments to measure gene expression changes in the dorsal h
Externí odkaz:
https://doaj.org/article/4e1648a9e9f345fe846dd5f4709f6c16
Autor:
Kazumi Kasahara, Keigo Hikishima, Mariko Nakata, Tomokazu Tsurugizawa, Noriyuki Higo, Kenji Doya
Publikováno v:
NeuroImage, Vol 299, Iss , Pp 120840- (2024)
Previous studies of operant learning have addressed neuronal activities and network changes in specific brain areas, such as the striatum, sensorimotor cortex, prefrontal/orbitofrontal cortices, and hippocampus. However, how changes in the whole-brai
Externí odkaz:
https://doaj.org/article/de6bbea46e3c4d819a05266ea03ab439
Autor:
Toru Takahata
Publikováno v:
Frontiers in Neural Circuits, Vol 18 (2024)
The existence of cortical columns, regarded as computational units underlying both lower and higher-order information processing, has long been associated with highly evolved brains, and previous studies suggested their absence in rodents. However, r
Externí odkaz:
https://doaj.org/article/e0d5abf0599a484c90143721d02e9f47
Autor:
A.B. Ozols, K.T. Meyers, C.C. Damphousse, J.M. Campbell, R. Khoshaba, S.G. Wallace, C. Hu, D.F. Marrone, A.L. Gallitano
Publikováno v:
Data in Brief, Vol 54, Iss , Pp 110365- (2024)
Although electroconvulsive therapy (ECT) is one of the most effective treatments for severe mood and psychotic disorders, the mechanisms underlying its therapeutic effects remain unknown. Electroconvulsive stimulation (ECS), the animal model for ECT,
Externí odkaz:
https://doaj.org/article/d456efc713474848bb6368c6ac960665
Publikováno v:
eLife, Vol 12 (2024)
Sexual bonds are central to the social lives of many species, including humans, and monogamous prairie voles have become the predominant model for investigating such attachments. We developed an automated whole-brain mapping pipeline to identify brai
Externí odkaz:
https://doaj.org/article/414d442846c54738a70b2f21a089fc63
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Human cytomegalovirus (HCMV) requires the robust expression of two immediate early proteins, IE1 and IE2, immediately upon infection to suppress the antiviral response and promote viral gene expression. While transcriptional control of IE1 a
Externí odkaz:
https://doaj.org/article/ccc81b91099b47a2a54e9e2ae7a19fed
Autor:
K.T. Meyers, C.C. Damphousse, A.B. Ozols, J.M. Campbell, J.M. Newbern, C. Hu, D.F. Marrone, A.L. Gallitano
Publikováno v:
Brain Stimulation, Vol 16, Iss 3, Pp 889-900 (2023)
Background: Despite being one of the safest, most effective treatments for severe mood disorders, the therapeutic mechanisms of electroconvulsive therapy remain unknown. Electroconvulsive seizure (ECS) induces rapid, high-level expression of immediat
Externí odkaz:
https://doaj.org/article/411738107aed4d8c8d9e80f5173ba75c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
First theorized by Hebb, neuronal ensembles have provided a framework for understanding how the mammalian brain operates, especially regarding learning and memory. Neuronal ensembles are discrete, sparsely distributed groups of neurons that become ac
Externí odkaz:
https://doaj.org/article/2d10898ec51f493da0d9ab2f7aed60b1
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Lysine demethylase KDM7A removes histone modifications H3K9me1/2 and H3K27me1/2. KDM7A plays critical roles in gene expression and contribute to biological processes including tumorigenesis, metabolism, and embryonic development. However, th
Externí odkaz:
https://doaj.org/article/2962ecd7ef0043029bb9c2c62fb1bab1