Zobrazeno 1 - 10
of 640
pro vyhledávání: '"IMIDs"'
Autor:
Pengyun Li, Xiaotong Hu, Zhiya Fan, Shiyang Sun, Qijie Ran, Ting Wei, Pengli Wei, Qiyu Jiang, Jian Yan, Ning Yang, Changkai Jia, Tingting Yang, Yaqiu Mao, Xu Cai, Tingting Xu, Zhiyuan Zhao, Xiaohong Qian, Weijie Qin, Xiaomei Zhuang, Feng Fan, Junhai Xiao, Zhibing Zheng, Song Li
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-30 (2024)
Abstract Background Targeted protein degradation of neosubstrates plays a crucial role in hematological cancer treatment involving immunomodulatory imide drugs (IMiDs) therapy. Nevertheless, the persistence of inevitable drug resistance and hematolog
Externí odkaz:
https://doaj.org/article/53485170677d439b9bf56471960e9a2e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nuria Perez-Diaz-del-Campo, Gian Paolo Caviglia, Giorgia La Piana, Marta Vernero, Valentina Schillaci, Angelo Armandi, Francesco Stalla, Demis Pitoni, Elisabetta Bugianesi, Alessia Ciancio, Paola Cavalla, Davide Giuseppe Ribaldone
Publikováno v:
Gastrointestinal Disorders, Vol 5, Iss 3, Pp 287-295 (2023)
Being two immune-mediated diseases (IMIDs), the association between multiple sclerosis (MS) and inflammatory bowel disease (IBD) is plausible, but data in the literature are conflicting. The aim of our study was to evaluate the possible association b
Externí odkaz:
https://doaj.org/article/69a6d5a24bf84859901cf9916e8ad910
Autor:
Carlo Di Gregorio, Matteo Tretti-Clementoni, Magda Belmontesi, Marina Romagnoli, Alessandro Innocenti, Malvina Zanchi, Lucia Leone, Giovanni Damiani, Ivano Iozzo
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 7, Pp 1603-1610 (2023)
Abstract Introduction Randomized controlled trials (RCTs) suggested that liquid formulation of botulinum toxin type A (aboBoNT-A) is safe and effective, but data confirming these characteristics in a real-life heterogenous set of patients are current
Externí odkaz:
https://doaj.org/article/ab41658341574ae9adea7f58c287201c
Autor:
Yu Wang, Shunsuke Shimosaki, Emi Ikebe, Hidekatsu Iha, Jun-ichi Yamamoto, Nichole Fife, Tomonaga Ichikawa, Mitsuo Hori, Masao Ogata, Yoshiyuki Tsukamoto, Naoki Hijiya, Masatsugu Moriyama, Shotaro Hagiwara, Shuichi Kusano, Masumichi Saito, Kamruddin Ahmed, Akira Nishizono, Hiroshi Handa, Kazuhiro Morishita
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasia associated with human T-cell leukemia virus type 1 (HTLV-1) infection and has an extremely poor prognosis. Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has
Externí odkaz:
https://doaj.org/article/c652ad6387c14272840172d06da6e59c
Autor:
Daniela Lecca, Shih-Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Abdul Mannan Baig, Neil Vargesson, Yu Kyung Kim, Inho Hwang, Sun Kim, Barry J. Hoffer, Yung-Hsiao Chiang, Nigel H. Greig
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-21 (2023)
Abstract Background Quelling microglial-induced excessive neuroinflammation is a potential treatment strategy across neurological disorders, including traumatic brain injury (TBI), and can be achieved by thalidomide-like drugs albeit this approved dr
Externí odkaz:
https://doaj.org/article/7c5613a4803945af9101f28f707d2991
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Enrico Milan, Annamaria Gullà
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/31345a50c9414151bf8b68dcfd8870dd
Publikováno v:
Sudan Journal of Medical Sciences, Vol 17, Iss 4, Pp 556-564 (2022)
Abstract A 53-year-old female presented with itchiness in her back. She has a 5 years history of tightness of the skin on her face, neck, and torso bilaterally. She did not have other symptoms suggestive of systemic sclerosis (scleroderma), and her r
Externí odkaz:
https://doaj.org/article/06dc2f2c5ad54e2293cfcfabf895b2e6
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1715-1723 (2022)
In the current study, we designed and synthesised a novel series of 2-(2,6-dioxopiperidin-3-yl)isoquinoline-1,3(2H,4H)-dione derivatives as cereblon (CRBN) modulators. The results of the CCK8 assay revealed potent antiproliferative activity for the s
Externí odkaz:
https://doaj.org/article/edb572fb88934f43a73df2318d77159e