Zobrazeno 1 - 10
of 65
pro vyhledávání: '"IMEPITOIN"'
Autor:
Giovanna Bruni, Doretta Capsoni, Anna Pellegrini, Angela Altomare, Mauro Coduri, Chiara Ferrara, Pietro Galinetto, Renato Molteni
Publikováno v:
Molecules, Vol 29, Iss 8, p 1724 (2024)
Scientific and industrial reasons dictate the study of the solid state of imepitoin, a highly safe and tolerable anticonvulsant drug used in the therapy of epileptic dogs that was approved in the Europe Union in 2013. Our investigations allowed us to
Externí odkaz:
https://doaj.org/article/98a860d7968348968a76a59570de1e18
Publikováno v:
Animals, Vol 14, Iss 4, p 545 (2024)
Imepitoin is a low-affinity partial agonist for benzodiazepine binding sites of gamma-aminobutyric acid receptors with anxiolytic effects. It has been shown to reduce anxiety during noise-related events in dogs when given at 30 mg/kg PO BID, although
Externí odkaz:
https://doaj.org/article/e8dbeb7504f34f5387fa2546d3346a89
Akademický článek
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Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 6, Pp 2675-2684 (2019)
Abstract Background Noise phobia is a common behavior problem in dogs for which there are limited treatment options. Objective To evaluate the efficacy and safety of imepitoin in comparison to placebo for the control of anxiety and fear associated wi
Externí odkaz:
https://doaj.org/article/205534e3d2e847b69cfac2ae2d009588
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Kevin J. McPeake, Daniel S. Mills
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-14 (2017)
Abstract Background Fear and anxiety based problems are common in dogs. Alongside behaviour modification programmes, a range of psychopharmacological agents may be recommended to treat such problems, but few are licensed for use in dogs and the onset
Externí odkaz:
https://doaj.org/article/f9423af9ca6c4d719b00ea158bcac24e
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-7 (2017)
Abstract Background Epilepsy in the cat is a serious medical condition. To date there are no licensed treatments for feline epilepsy and no well-controlled clinical studies on the efficacy or safety of antiepileptic drugs in cats. The aim of this stu
Externí odkaz:
https://doaj.org/article/fad9332b574f4c90a8275059c9d07528
Autor:
Sophie Elizabeth Wyatt
Publikováno v:
Veterinary Evidence, Vol 4, Iss 2 (2019)
PICO questionIn adult cats with idiopathic epilepsy, which is poorly controlled with phenobarbital monotherapy, should levetiracetam or imepitoin be used in preference as a second line treatment in order to reduce seizure frequency?Clinical bottom li
Externí odkaz:
https://doaj.org/article/d5a717d0d11d42538f145bbd9cd28406
Autor:
Odilo Engel, Aleksandar Masic, Gary Landsberg, Melissa Brooks, Daniel S. Mills, Chris Rundfeldt
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Imepitoin is a low affinity partial agonist for the benzodiazepine binding site of γ-aminobutyric acid (GABAA) receptors, and is currently used as an antiepileptic in dogs. Here we tested imepitoin for anxiolytic properties. In an in vitro model, im
Externí odkaz:
https://doaj.org/article/3ef5d82247e84e80bfef1b5b20f9d8ae
Autor:
Hamers, Maud, Plonek, Marta, Bhatti, Sofie F M, Bergknut, Niklas, Diaz Espineira, Montse, Santifort, Koen Maurits, Mandigers, Paul, CS_Welfare & emerging diseases, Interne geneeskunde GD, CS_Genetics
Publikováno v:
FRONTIERS IN VETERINARY SCIENCE
Frontiers in Veterinary Science, 9. Frontiers Media S.A.
Frontiers in Veterinary Science, 9. Frontiers Media S.A.
Epilepsy in dogs is a common chronic and serious disorder and may have an impact on the quality of life of the owners as well as the dogs themselves. The aim of this pilot study was to investigate the QoL score of dogs suffering from idiopathic epile