Výsledky vyhledávání - "IM, intramuscular"

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A multidisciplinary approach to optimizing care of patients treated with alpelisib

Autor: Rugo, Hope S., Lacouture, Mario E., Goncalves, Marcus D., Masharani, Umesh, Aapro, Matti S., O'Shaughnessy, Joyce A.

Publikováno v: Breast, Vol 61, Iss, Pp 156-167 (2022)
The Breast : Official Journal of the European Society of Mastology

Purpose The oral, α-specific phosphatidylinositol-3-kinase (PI3Kα) inhibitor alpelisib is the first PI3K inhibitor approved for the treatment of advanced breast cancer. As alpelisib is a relatively new therapeutic option, specific guidance and a mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed100c67c3edaa21648be43be27980e
https://doi.org/10.1016/j.breast.2021.12.016

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Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19

Autor: Eric Destexhe, Sarah Paris-Robidas, Charlotte Dubé, Nathalie Landry, Sonia Trépanier, Iryna Primakova, Brian J. Ward

Publikováno v: Reproductive Toxicology (Elmsford, N.y.)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection resulting in the coronavirus disease 2019 (COVID-19) has afflicted tens of millions of people in a worldwide pandemic. A recently developed recombinant Plant-Derived Virus-Like Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf32aa4c40e95ebded16735f4c91d8cb
http://europepmc.org/articles/PMC8611889

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Evaluation of Systemic and Mucosal Immune Responses Induced by a Nasal Powder Delivery System in Conjunction with an OVA Antigen in Cynomolgus Monkeys

Autor: Keita Sasaki, Akifumi Kyuno, Shunji Haruta, Yuji Sasaki, Akihide Tanimoto, Yusuke Torikai

Publikováno v: Journal of Pharmaceutical Sciences

An immune response for a nasal ovalbumin (OVA) powder formulation with an applied nasal delivery platform technology, consisting of a powdery nasal carrier and a device, was evaluated in monkeys with similar upper respiratory tracts and immune system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebe856837a1444a730e623a41003518
https://doi.org/10.1016/j.xphs.2020.11.023

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Self-assembled mRNA vaccines

Autor: Yulia Eygeris, Gaurav Sahay, Mohit Gupta, Jeonghwan Kim

Publikováno v: Advanced Drug Delivery Reviews

mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology, and nanotechnology have generated interest in delivering safe and effective mRNA th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0f88a1e945504ba8b4af825e8da083
https://doi.org/10.1016/j.addr.2020.12.014

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Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke

Autor: Xueyuan Yang, Soo K. Shin, Jin Xie, Kylee J. Duberstein, Madison M. Fagan, Simon R. Platt, Kelly M. Scheulin, Erin E. Kaiser, Holly A. Kinder, Elizabeth S. Waters, Julie Jeon, Franklin D. West, Anil Kumar, Hea Jin Park

Publikováno v: IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)

Background The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f797c86f00c6b2f76590c2d6fd382a6
http://europepmc.org/articles/PMC8019951

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Regenerative effect of mesenteric fat stem cells on ccl4-induced liver cirrhosis, an experimental study

Autor: Fatemeh Namazi, Seifollah Dehghani Nazhvani, Iman Haghani, Abbas Ghaderi, Fatemeh Dehghani Nazhvani

Publikováno v: Annals of Medicine and Surgery

Background Liver cirrhosis is a chronic disease in which normal liver tissue is replaced by fibrous tissue, leads to liver malfunction. Although transplantation is the most certain cure, stem cell therapies are shedding light on efforts to regenerate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e51e3c9f52533e5f37abaa05301d5f
http://europepmc.org/articles/PMC7593263

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Gynecomastia in a Transgender Boy: A Case Report

Autor: Raymond Fung, Mary Kathleen Greenaway, Giancarlo McEvenue

Publikováno v: AACE Clinical Case Reports
AACE Clinical Case Reports, Vol 7, Iss 6, Pp 350-352 (2021)

Objective To describe the case of a 17-year-old transgender boy who experienced breast development while on testosterone, having been suppressed with a gonadotropin-releasing hormone (GnRH) agonist prior to testosterone therapy Case report A 17-year-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33e50dfbb5412614764ab6f5e81197b
http://europepmc.org/articles/PMC8573277

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