Zobrazeno 1 - 10 of 187 pro vyhledávání: '"ILCE MARA DE SYLLOS CÓLUS"'
1
Flavonoid brachydin B decreases viability, proliferation, and migration in human metastatic prostate (DU145) cells grown in 2D and 3D culture models
Autor: Juliana Mara Serpeloni, Diego Luis Ribeiro, Gabriela Fátima Weiss, Larissa Cristina Bastos de Oliveira, Andressa Yuri Fujiike, Higor Lopes Nunes, Claudia Quintino da Rocha, Roberta Losi Guembarovski, Ilce Mara de Syllos Cólus
Publikováno v: Toxicology Research. 12:321-331
Brachydin B (BrB) is a unique dimeric flavonoid extracted from Fridericia platyphylla (Cham.) LG Lohmann with different biological activities. However, the antitumoral potential of this flavonoid is unclear. In our study, we evaluated the effects of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb17ecea93aba8b32111916d103be45c
https://doi.org/10.1093/toxres/tfad019
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2
Akademický článek
The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death
Autor: Diego Luis Ribeiro, Katiuska Tuttis, Larissa Cristina Bastos de Oliveira, Juliana Mara Serpeloni, Izabela Natalia Faria Gomes, André van Helvoort Lengert, Cláudia Quintino da Rocha, Rui Manuel Reis, Ilce Mara de Syllos Cólus, Lusânia Maria Greggi Antunes
Publikováno v: Pharmaceutics, Vol 14, Iss 5, p 963 (2022)
Metastatic prostate cancer (mPCa) is resistant to several chemotherapeutic agents. Brachydin A (BrA), a glycosylated flavonoid extracted from Fridericia platyphylla, displays a remarkable antitumoral effect against in vitro mPCa cells cultured as bid
Externí odkaz: https://doaj.org/article/4103b00b4aa24c56aa0ab2528370ac2c
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4
Akademický článek
Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression
Autor: Manoela Viar Fogaça, Priscila de Matos Cândido-Bacani, Lucas Milanez Benicio, Lara Martinelli Zapata, Priscilla de Freitas Cardoso, Marcelo Tempesta de Oliveira, Tamara Regina Calvo, Eliana Aparecida Varanda, Wagner Vilegas, Ilce Mara de Syllos Cólus
Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 2005-2014 (2017)
Context: Indigofera suffruticosa Miller (Fabaceae) and I. truxillensis Kunth produce compounds, such as isatin (ISA) and indirubin (IRN), which possess antitumour properties. Their effects in mammalian cells are still not very well understood. Object
Externí odkaz: https://doaj.org/article/61056a3a62eb4099a13754b8c083efe3
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5
The potential of cell-free and exosomal microRNAs as biomarkers in liquid biopsy in patients with prostate cancer
Autor: Monyse de Nóbrega, Mariana Bisarro dos Reis, Érica Romão Pereira, Marilesia Ferreira de Souza, Ilce Mara de Syllos Cólus
Publikováno v: Journal of Cancer Research and Clinical Oncology. 148:2893-2910
Prostate cancer (PCa) is the 4th most diagnosed cancer and the 8th leading cause of cancer-related death worldwide. Currently, clinical risk stratification models including factors like PSA levels, Gleason score, and digital rectal examination are us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c50e0d393f6a6f3d7046efca7022de
https://doi.org/10.1007/s00432-022-04213-9
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6
An
Autor: Hector Hugo, Furini, Kevin Santiago DE Souza Quenzo, Fukushima, Monyse, DE Nóbrega, Marilesia Ferreira, DE Souza, Milene Roldão Souza, Rodrigues, Beatriz Bocatte, DE Mattos, Roberta Losi, Guembarovski, Paulo Emílio, Fuganti, Andrea Name Colado, Simão, Tamires, Flauzino, Ilce Mara DE Syllos, Cólus
Publikováno v: Anticancer research. 43(1)
Prostate cancer (PCa) is one of the most frequent neoplasms in men around the world. In recent years, the search for new biomarkers with greater prognostic potential for PCa has intensified. This study aimed to evaluate single nucleotide polymorphism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7105e3568e30dfee3c23cbd2aa41ae3
https://pubmed.ncbi.nlm.nih.gov/36585213
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7
Aglycone flavonoid brachydin A shows selective cytotoxicity and antitumoral activity in human metastatic prostate (DU145) cancer cells
Autor: Juliana Mara Serpeloni, Ilce Mara de Syllos Cólus, Larissa Cristina Bastos de Oliveira, Higor Lopes Nunes, Diego Luis Ribeiro, Cláudia Quintino da Rocha, Jessyane Rodrigues do Nascimento
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Cytotechnology
Made available in DSpace on 2022-04-28T19:45:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 In prostate cancer, flavonoids possess a wide variety of anticancer effects, focused on the antioxidant/pro-oxidant activity, inactivation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffc43add8f04647900f719672092ff7
https://doi.org/10.1007/s10616-021-00495-y
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8
Akademický článek
Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer.
Autor: Marilesia Ferreira de Souza, Hellen Kuasne, Mateus de Camargo Barros-Filho, Heloísa Lizotti Cilião, Fabio Albuquerque Marchi, Paulo Emilio Fuganti, Alexandre Rossi Paschoal, Silvia Regina Rogatto, Ilce Mara de Syllos Cólus
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184094 (2017)
Circulating nucleic acids are found in free form in body fluids and may serve as minimally invasive tools for cancer diagnosis and prognosis. Only a few studies have investigated the potential application of circulating mRNAs and microRNAs (miRNAs) i
Externí odkaz: https://doaj.org/article/4dcf93b7f4c64c5db1234baa7deb25d6
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9
Elaborando a Capacitação de Tutores: Subsídios da Prática
Autor: Rosa Elisa Carvalho Linhares, Henriqueta Galvanin Guidio de Almeida, Olavo Franco Ferreira, Adriana Cavalcanti de Aguiar, Olga Chizue Takahashi, Ilce Mara de Syllos Cólus
Publikováno v: Revista Brasileira de Educação Médica, Vol 27, Iss 3, Pp 191-199 (2021)
Revista Brasileira de Educação Médica, Volume: 27, Issue: 3, Pages: 191-199, Published: 18 JUN 2021
Revista Brasileira de Educação Médica v.27 n.3 2003
Revista Brasileira de Educação Médica
Associação Brasileira de Educação Médica (ABEM)
instacron:ABEM
Resumo: O Curso de Medicina da Universidade Estadual de Londrina Implementou em 1998 uma profunda mudança do currículo, adotando como estratégia a Aprendizagem Baseada em Problemas. Esta demanda o desempenho de novos e complexos papéis por parte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a631dcd162f80900c134d5e2c9e4cd66
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-55022003000300191&tlng=pt
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10
Visão Docente do Processo de Implementação da Aprendizagem Baseada em Problemas (ABP) no Curso Médico da Universidade Estadual de Londrina (UEL)
Autor: Ilce Mara de Syllos Cólus, Olavo Franco Ferreira Filho, Adriana Cavalcanti de Aguiar, Henriqueta Galvanin Guidio de Almeida, Pedro Alejandro Gordan, Hermann Iark Oberdiek, Rosa Elisa Carvalho Linhares
Publikováno v: Revista Brasileira de Educação Médica, Vol 26, Iss 3, Pp 175-183 (2021)
Revista Brasileira de Educação Médica, Volume: 26, Issue: 3, Pages: 175-183, Published: 25 JUN 2021
Revista Brasileira de Educação Médica v.26 n.3 2002
Revista Brasileira de Educação Médica
Associação Brasileira de Educação Médica (ABEM)
instacron:ABEM
Resumo: Objetivo: Conhecer a visão dos docentes do curso de Medicina da UEL a respeito do processo de implantação e do momento atual do novo currículo em ABP. Método: Aplicação de um questionário aos 268 docentes envolvidos com o curso e aval
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e977896a4e3ec04ae63cba58aaa6207
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-55022002000300175&tlng=pt
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