Zobrazeno 1 - 10
of 38
pro vyhledávání: '"ILC, innate lymphoid cell"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 843-856 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The epithelial lining of the intestine, particularly the stem cell compartment, is affected by harsh conditions in the luminal environment and also is susceptible to genotoxic agents such as radiation and chemotherapy. Therefore, the ability for inte
Autor:
Kasper Hoebe, Shrinivas Bishu, John Y. Kao, Varsha Ganesan, Ankit Sharma, Yanfen Yang, Chang Zeng, Rodney D. Newberry, Sahiti Marella, Simon P. Hogan, Philip D. King, Ariel Munitz, Jazib Uddin, Taeko K. Noah, Lee A. Denson, Andrew R. Patterson, Simone Vanoni, Lisa Waggoner, Senad Divanovic, Paul S. Foster, Michael J. Rosen, S. M. S. Tomar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)
Background & Aims CD4+ T cells are regulated by activating and inhibitory cues, and dysregulation of these proper regulatory inputs predisposes these cells to aberrant inflammation and exacerbation of disease. We investigated the role of the inhibito
Autor:
Aralia Leon-Coria, Manish Kumar, Matthew Workentine, France Moreau, Michael Surette, Kris Chadee
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Background & Aims Alterations in intestinal MUC2 mucin and microbial diversity are closely linked with important intestinal pathologies; however, their impact on each other and on intestinal pathogenesis has been vaguely characterized. Therefore, it
Autor:
Jakob Benedict Seidelin, Jens Vilstrup Johansen, Marina Ramírez Galera, Lene Riis, Tine Rask Licht, Benjamin E. Mead, Anders Woetmann, Martin Iain Bahl, Jeffrey M. Karp, Jacob Tveiten Bjerrum
Publikováno v:
Seidelin, J B, Bahl, M I, Licht, T R, Mead, B E, Karp, J M, Johansen, J V, Riis, L B, Galera, M R, Woetmann, A & Bjerrum, J T 2021, ' Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans ', Cellular and Molecular Gastroenterology and Hepatology, vol. 12, no. 4, pp. 1281-1296 . https://doi.org/10.1016/j.jcmgh.2021.06.002
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1281-1296 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1281-1296 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Background and aims The trigger hypothesis opens the possibility of anti-flare initiation therapies by stating that ulcerative colitis (UC) flares originate from inadequate responses to acute mucosal injuries. However, experimental evidence is restri
Autor:
Anthony M. Diomino, David A. Brenner, Hyeok Choon Kwon, Gibraan Rahman, Sara Brin Rosenthal, Tatiana Kisseleva, Linshan Shang, Souradipta Ganguly, Ruoyu Wang, Debanjan Dhar, Rob Knight, Pejman Soorosh, Mojgan Hosseini, Yanhan Wang, Bernd Schnabl, German R. Aleman Muench
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 891-920 (2021)
Cellular and molecular gastroenterology and hepatology, vol 12, iss 3
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 891-920 (2021)
Cellular and molecular gastroenterology and hepatology, vol 12, iss 3
Background & Aims How benign liver steatosis progresses to nonalcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC) remains elusive. NASH progression entails diverse pathogenic mechanisms and relies on complex cross-talk betw
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Celiac disease (CD) is a common autoimmune disorder triggered by the ingestion of gluten in genetically susceptible individuals. Although the mechanisms underlying gliadin-mediated activation of adaptive immunity in CD have been well-characterized, r
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2962-2971 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2962-2971 (2020)
The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. T
Autor:
Luca Di Martino, Carlo De Salvo, Kristine-Ann Buela, Christopher Hager, Mahmoud Ghannoum, Abdullah Osme, Ludovica Buttò, Giorgos Bamias, Theresa T. Pizarro, Fabio Cominelli
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 901-923 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 901-923 (2022)
Background & Aims We previously showed that abundance of Candida tropicalis is significantly greater in Crohn’s disease patients compared with first-degree relatives without Crohn’s disease. The aim of this study was to determine the effects and
Autor:
Ryo Aoki, Toshiaki Teratani, Mari Mochizuki Arai, Kentaro Miyamoto, Yohei Mikami, Shinta Mizuno, Yosuke Harada, Ena Nomura, Takanori Kanai, Tomohisa Sujino, Hiroki Kiyohara, Makoto Naganuma, Yuzo Koda, Tadakazu Hisamatsu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Background & Aims Psoriasis and inflammatory bowel disease (IBD) are both chronic inflammatory diseases occurring in the skin and gut, respectively. It is well established that psoriasis and IBD have high concordance rates, and similar changes in imm
Autor:
Leigh Ann Samsa, Michael A. Daniele, Adam D. Gracz, Bailey Zwarycz, Joshua Starmer, Luisa Salter-Cid, Qihong Zhao, Scott T. Magness, Kristina R. Rivera, Ian A. Williamson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 1-17 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 1-17 (2019)
Background & Aims Crohn’s disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in Crohn’s disease and are associated with disrup