Zobrazeno 1 - 10
of 124
pro vyhledávání: '"IL11"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 5309-5326 (2023)
Jiaming He,1,2,* Tiankuo Luan,3,* Gang Zhao,4 Yingxue Yang5 1Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Institute of
Externí odkaz:
https://doaj.org/article/a5a10d96845341a99988c0430ab3ce0f
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Macrophage filopodia, which are dynamic nanotube-like protrusions, have mainly been studied in the context of pathogen clearance. The mechanisms by which they facilitate intercellular communication and mediate tissue inflammation remain poor
Externí odkaz:
https://doaj.org/article/067dcf397d2844ad97935a9e6758898f
Autor:
Yunhao Tan, Kenta Mosallanejad, Qingxiu Zhang, Stephen O’Brien, Meghan Clements, Stuart Perper, Sarah Wilson, Sudiksha Chaulagain, Jing Wang, Mary Abdalla, Helen Al-Saidi, Danyal Butt, Anca Clabbers, Kwasi Ofori, Beth Dillon, Bohdan Harvey, John Memmott, Christopher Negron, David Winarta, Catherine Tan, Amlan Biswas, Feng Dong, Vanessa Morales-Tirado, Xiaoqing Lu, Gurminder Singh, Michael White, Shanna Ashley, Heather Knight, Susan Westmoreland, Lucy Phillips, Tracy Carr, Lauren Reinke-Breen, Rajeeva Singh, Jianwen Xu, Kan Wu, Lisa Rinaldi, Brian Stoll, Yupeng David He, Lisa Hazelwood, Jozsef Karman, Andrew McCluskey, William Stine, Ivan Correia, Stephen Gauld, Marc C. Levesque, Geertruida Veldman, Cedric Hubeau, Timothy Radstake, Ramkrishna Sadhukhan, Edda Fiebiger
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Fibrotic diseases, such as idiopathic pulmonary fibrosis (IPF) and systemic scleroderma (SSc), are commonly associated with high morbidity and mortality, thereby representing a significant unmet medical need. Interleukin 11 (IL11)-mediated cell activ
Externí odkaz:
https://doaj.org/article/6fa4a13cb80640969f85235ea03fd692
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-27 (2023)
Abstract Background The pathogenic mechanisms shared between kidney stones and diabetes at the transcriptional level remain elusive, and the molecular mechanisms by which resveratrol exerts its protective effects against these conditions require furt
Externí odkaz:
https://doaj.org/article/2b0db83c51f14958bd0e2e80219394c4
Publikováno v:
Nutrients, Vol 16, Iss 9, p 1342 (2024)
Nearly every fifth adult in the United States and many older adults worldwide are affected by chronic kidney disease (CKD), which can progress to kidney failure requiring invasive kidney replacement therapy. In this review, we briefly examine the pat
Externí odkaz:
https://doaj.org/article/cd5a7648b9994068acde3f06007569a9
Autor:
Anissa A. Widjaja, Stuart A. Cook
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1363 (2024)
IL6 is a proinflammatory cytokine that binds to membrane-bound IL6 receptor (IL6R) or soluble IL6R to signal via gp130 in cis or trans, respectively. We tested the hypothesis that sgp130Fc, which is believed to be a selective IL6 trans-signalling inh
Externí odkaz:
https://doaj.org/article/9716bd1f473b4e3ca452492c453354d8
Akademický článek
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Autor:
Blanca D. López-Ayllón, Ana de Lucas-Rius, Laura Mendoza-García, Tránsito García-García, Raúl Fernández-Rodríguez, José M. Suárez-Cárdenas, Fátima Milhano Santos, Fernando Corrales, Natalia Redondo, Federica Pedrucci, Sara Zaldívar-López, Ángeles Jiménez-Marín, Juan J. Garrido, María Montoya
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
SARS-CoV-2, the cause of the COVID-19 pandemic, possesses eleven accessory proteins encoded in its genome. Their roles during infection are still not completely understood. In this study, transcriptomics analysis revealed that both WNT5A and IL11 wer
Externí odkaz:
https://doaj.org/article/499e50e13f3e48b89f101c68b9fb0617
Autor:
Miriam T. Kastlmeier, Erika Gonzalez-Rodriguez, Phoebe Cabanis, Eva M. Guenther, Ann-Christine König, Lianyong Han, Stefanie M. Hauck, Fenja See, Sara Asgharpour, Christina Bukas, Gerald Burgstaller, Marie Piraud, Mareike Lehmann, Rudolf A. Hatz, Jürgen Behr, Tobias Stoeger, Anne Hilgendorff, Carola Voss
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInterstitial lung disease (ILD) is a heterogenous group of lung disorders where destruction and incomplete regeneration of the lung parenchyma often results in persistent architectural distortion of the pulmonary scaffold. Continuous mese
Externí odkaz:
https://doaj.org/article/5bf9ea6ed1794e0b87a4a953658f0383
Autor:
Layla Panahipour, Azarakhsh Oladzad Abbasabadi, Anja Wagner, Klaus Kratochwill, Monika Pichler, Reinhard Gruber
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16181 (2023)
Bone allografts are widely used as osteoconductive support to guide bone regrowth. Bone allografts are more than a scaffold for the immigrating cells as they maintain some bioactivity of the original bone matrix. Yet, it remains unclear how immigrati
Externí odkaz:
https://doaj.org/article/6d3e0cba6129482f8e73c13b9599507c