Zobrazeno 1 - 10
of 93
pro vyhledávání: '"IL10RA"'
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e22968- (2024)
To identify candidate pathogenic genes of early-stage Crohn's disease (CD) and predict potential roles of genetic factors in CD, we performed whole exome sequencing on a child with early-stage Crohn's disease (CD) and her parents (core family), found
Externí odkaz:
https://doaj.org/article/7ee12cc94fd24f81815410ca13cc4c15
Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 2361-2376 (2022)
Chao Wang,1,2,* Zhihong Chen,1,2,* Xueming Yang,1,3,* Wei Zhang,1 Junbo Zhou,4 Hongchuang Zhang,5 Xu Ding,1,2 Jinhai Ye,1,2 Heming Wu,1,2 Yunong Wu,1,2 Yang Zheng,1,6 Xiaomeng Song1,2 1Jiangsu Key Laboratory of Oral Diseases, Nanjing Medi
Externí odkaz:
https://doaj.org/article/c198dcece000404ca31ce7db99104c93
Autor:
Milka Grk, Rada Miskovic, Ivica Jeremic, Milica Basaric, Marija Dusanovic Pjevic, Biljana Jekic, Danijela Miljanovic, Ivana Lazarevic, Aleksa Despotovic, Andja Cirkovic, Ana Banko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11292 (2023)
Systemic lupus erythematosus (SLE) is characterized by an imbalance between proinflammatory and anti-inflammatory mediators. Single-nucleotide polymorphisms (SNPs) in genes coding IL10RA, IL10RB, and IL22RA could affect their expression or function a
Externí odkaz:
https://doaj.org/article/147332754d2a45b9a067f6c3566573e9
Akademický článek
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Autor:
Sanjay Mallikarjunappa, Umesh K. Shandilya, Ankita Sharma, Kristen Lamers, Nathalie Bissonnette, Niel A. Karrow, Kieran G. Meade
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many
Externí odkaz:
https://doaj.org/article/bb5bde68719d4267835330771ffa4ac0
Akademický článek
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Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Very early-onset inflammatory bowel disease (VEO-IBD) is defined as IBD diagnosed in children younger than 6 years of age. VEO-IBD is often associated with a monogenic etiology or primary immune deficiency. Here, we report the case of a 7-month-old C
Externí odkaz:
https://doaj.org/article/333e3348a9004011afc00519d08e606b
Autor:
Mengmeng Dou, Xueliang Zhou, Lifeng Li, Mingliang Zhang, Wenbin Wang, Mengru Wang, Yilei Jing, Rui Ma, Jie Zhao, Lin Zhu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The etiology of multiple sclerosis (MS) is not clear, and the treatment of MS presents a great challenge. This study aimed to investigate the pathogenesis and potential therapeutic targets of MS and to define target genes of matrine, a quinolizidine
Externí odkaz:
https://doaj.org/article/94e4a43c7b2942f1ab9c3b93a3e14aa7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Skin cutaneous melanoma (SKCM) is the major cause of death for skin cancer patients, its high metastasis often leads to poor prognosis of patients with malignant melanoma. However, the molecular mechanisms underlying metastatic melanoma remain to be
Externí odkaz:
https://doaj.org/article/42468153e01b454c8d091ad481162da4
Autor:
Aijuan Xue, Xiaowen Qian, Xuefeng Gao, Ping Wang, Lin Wang, Cuifang Zheng, Zhiheng Huang, Wenhui Hu, Jieru Shi, Ying Huang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
ObjectivesUmbilical cord blood transplantation (UCBT) is associated with a relatively high rate of engraftment failure. This study aimed at exploring whether any fecal microbiota could be associated with engraftment failure following UCBT in Crohn’
Externí odkaz:
https://doaj.org/article/e5fff5b29f3c41c683d58721393bb2dd