Výsledky vyhledávání - "IL-6 (interleukin 6)"

Akademický článek

Advancing the understanding of venetoclax in t(11;14)-positive multiple myeloma: a comprehensive review of clinical evidence and future prospects

Autor: Abdullah AlZahrani, Nada Alsuhebany, Imran K. Tailor, Abdullah M. Alrajhi

Publikováno v: Hematology, Vol 29, Iss 1 (2024)

ABSTRACTVenetoclax is a selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (BCL2), as a targeted therapy for multiple myeloma (MM) patients. It was initially approved by the United States Food and Drug Administration for the treatmen

Externí odkaz: https://doaj.org/article/9c59153d5af146aeb7865719eb56c1fe

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Akademický článek

The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality

Autor: Wolszczak-Biedrzycka B, Dorf J, Milewska A, Łukaszyk M, Naumnik W, Kosidło JW, Dymicka-Piekarska V

Publikováno v: Journal of Inflammation Research, Vol Volume 16, Pp 2173-2188 (2023)

Blanka Wolszczak-Biedrzycka,1 Justyna Dorf,2 Anna Milewska,3 Mateusz Łukaszyk,4 Wojciech Naumnik,4 Jakub Wiktor Kosidło,5 Violetta Dymicka-Piekarska2 1Department of Psychology and Sociology of Health and Public Health, University of War

Externí odkaz: https://doaj.org/article/2e7b63facd6748d49665a6bd822c6206

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Akademický článek

Effect of long-chain omega-3 polyunsaturated fatty acids on cardiometabolic factors in children with acute lymphoblastic leukemia undergoing treatment: a secondary analysis of a randomized controlled trial

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

IntroductionIncreased triglycerides (TGs) are a major risk factor for cardiovascular disease. Furthermore, hypertriglyceridemia is commonly associated with a reduction of high-density lipoprotein cholesterol (HDL-C) and an increase in atherogenic sma

Externí odkaz: https://doaj.org/article/1873c33ee56b451080bc79da40376683

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Akademický článek

A tryptophan metabolite prevents depletion of circulating endothelial progenitor cells in systemic low-grade inflammation

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundChronic systemic inflammation reduces the bioavailability of circulating endothelial progenitor cells (EPCs). Indoleamine 2,3-dioxygenase 1 (IDO1), a key enzyme of immune tolerance catalyzing the initial step of tryptophan degradation along

Externí odkaz: https://doaj.org/article/e0038b3f27ff43599e3454e2cc25ae8e

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Akademický článek

CCN1 Promotes Inflammation by Inducing IL-6 Production via α6β1/PI3K/Akt/NF-κB Pathway in Autoimmune Hepatitis

Autor: Renquan Jiang, Jifeng Tang, Xuehao Zhang, Yujue He, Ziqing Yu, Shuhui Chen, Jinfang Xia, Jinpiao Lin, Qishui Ou

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease with unknown etiology. CCN1, an extracellular matrix-associated protein, is associated with carcinoma, inflammation, liver fibrosis, and even autoimmune diseases. However, the role th

Externí odkaz: https://doaj.org/article/ac11d6cf9b6e4203939bed0a42498185

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Akademický článek

Relationship Between Cardiovascular Disease Pathology and Fatal Opioid and Other Sedative Overdose: A Post-Mortem Investigation and Pilot Study

Autor: Abdulmalik Zuhair Arab, Aldo Alberto Conti, Fleur Davey, Faisel Khan, Alexander Mario Baldacchino

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Introduction: In 2019, Scotland reported the highest number of drug deaths amongst EU countries. Of the 1,264 drug deaths reported in 2019, 94% were related to polysedative use. Studies have proposed a relationship between opioid use and cardiovascul

Externí odkaz: https://doaj.org/article/a851ea49acd54409b1cbc6a84a94425b

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