Zobrazeno 1 - 10
of 544
pro vyhledávání: '"IL-1BETA"'
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background The purinergic receptor P2X7 plays a crucial role in infection, inflammation, and cell death. It is thought that P2X7 receptor stimulation triggers processing and release of the pro-inflammatory cytokine interleukin (IL)-1β by ac
Externí odkaz:
https://doaj.org/article/67311714292949e789a807e78b9e0188
Autor:
Денис Сергеевич Загрешенко, Андрей Владимирович Климов, Владимир Васильевич Климов, Наталья Сергеевна Кошкарова, Оксана Анатольевна Найдина, Екатерина Юрьевна Цыплина
Publikováno v:
Medicina v Kuzbasse, Vol 22, Iss 3, Pp 21-26 (2023)
The review article focuses on the NLRP1 inflammasome, which was discovered before the others but has been the least investigated. The emergence of the inflammasome in innate immunity container cells is an early event that precedes the development of
Externí odkaz:
https://doaj.org/article/9ff1394973994118a7734c2bc53832e8
Autor:
Melike Tetik, Betül Önder Uzgan, Cansu Aykaç, Burcu Ekinci, Tutku Yaraş, Aykut Kuruoğlu, Özge Akgül, Tunç Alkın
Publikováno v:
Klinik Psikiyatri Dergisi, Vol 25, Iss 1, Pp 75-83 (2022)
INTRODUCTION: It is now well accepted that inflammatory processes play a role in the etiopathogenesis of psychiatric disorders. NLRP3 inflammasome, which is formed by the combination of NLRP3, ASC and Caspase-1 proteins, and its activator NEK7, takes
Externí odkaz:
https://doaj.org/article/7be2205be04a47618b9c962aa17e2902
Publikováno v:
Türk Nöroloji Dergisi, Vol 27, Iss 4, Pp 390-393 (2021)
Objective: We aimed to determine the association between a polymorphism in the promoter region of the IL-1beta gene resulting in enhanced gene transcription and the clinical phenotype of temporal lobe epilepsy with hippocampal sclerosis (TLE+HS). Ma
Externí odkaz:
https://doaj.org/article/66f0c4448d2d45d2a2fa7369d8cce573
Autor:
Matthias Hepprich, Jonathan M. Mudry, Claudia Gregoriano, Francois R. Jornayvaz, Sebastian Carballo, Anne Wojtusciszyn, Pierre-Alexandre Bart, Jean-Daniel Chiche, Stefan Fischli, Thomas Baumgartner, Claudia Cavelti-Weder, Dominique L. Braun, Huldrych F. Günthard, Felix Beuschlein, Anna Conen, Emily West, Egon Isenring, Stefan Zechmann, Gabriela Bucklar, Yoann Aubry, Ludovic Dey, Beat Müller, Patrick Hunziker, Philipp Schütz, Marco Cattaneo, Marc Y. Donath
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101649- (2022)
Summary: Background: Patients with type 2 diabetes and obesity have chronic activation of the innate immune system possibly contributing to the higher risk of hyperinflammatory response to SARS-CoV2 and severe COVID-19 observed in this population. We
Externí odkaz:
https://doaj.org/article/197006e344dd4ae1bdcf99258310af46
Autor:
Xiao Ma, Fang Nan, Hantian Liang, Panyin Shu, Xinzou Fan, Xiaoshuang Song, Yanfeng Hou, Dunfang Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
High sugar intake has long been recognized as a potential environmental risk factor for increased incidence of many non-communicable diseases, including obesity, cardiovascular disease, metabolic syndrome, and type 2 diabetes (T2D). Dietary sugars ar
Externí odkaz:
https://doaj.org/article/33bfed9c70c4445faf3e5f9953a3cc17
Akademický článek
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Akademický článek
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Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 21, Iss , Pp 100433- (2022)
Greater inflammatory signaling has been shown to promote breast cancer disease progression and poorer clinical outcomes. Lower social support and social well-being have been related to greater inflammatory signaling and poorer clinical outcomes in wo
Externí odkaz:
https://doaj.org/article/52ec7bd590a64381ae62e63067fe2f29
Autor:
Guangdi Li, Mi Zhang, Yuan Huang, Jiafei Yang, Lianghong Dong, Hao Shi, Long Li, Riguang Liu, Jiangwei Li
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background This study aimed to investigate the effect of abnormal Core binding factor-β expression on proliferation, differentiation and apoptosis of chondrocytes, and elucidate the relationship between Core binding factor-β and osteoarthr
Externí odkaz:
https://doaj.org/article/948309a2eb844a2bb809bfd5705819cc