Zobrazeno 1 - 10
of 3 787
pro vyhledávání: '"IL-15"'
Publikováno v:
ImmunoTargets and Therapy, Vol Volume 13, Pp 513-524 (2024)
Sumei Chen,1,* Lingrong Yang,2,* Bing Xia,3 Haitao Zhu,4 Zhenghao Piao,5 Youssef Jounaidi6 1Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang, 310002, People’s Republic of China; 2Department of Hangzhou Cancer I
Externí odkaz:
https://doaj.org/article/35e0411b4a9549f1a4fdb3dd324e59ba
Autor:
Cheng-Jung Sung, Leanne S. Whitmore, Elise Smith, Jean Chang, Jennifer Tisoncik-Go, Aaron Barber-Axthelm, Andrea Selseth, Shana Feltham, Sohita Ojha, Scott G. Hansen, Louis J. Picker, Michael Gale
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) is a deadly infectious disease having a major impact on global health. Using the CMV vector for development of novel vaccines is a promising new strategy that elicits strong and durable, h
Externí odkaz:
https://doaj.org/article/b235f6cd8b354ad396e5a45f5c3a4336
Autor:
Shaojie Hu, Kelin Meng, Tianlai Wang, Rirong Qu, Boyu Wang, Yu Xi, Taiyan Yu, Zhiwei Yuan, Zihao Cai, Yitao Tian, Chenxi Zeng, Xue Wang, Wenbin Zou, Xiangning Fu, Lequn Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Background IL-15 plays a vital role in enhancing NK cell- and T-cell-mediated antitumor immune responses; however, the direct effect of IL-15 on tumor cells has not been fully elucidated. Herein, we investigated the effect of IL-15 on lung a
Externí odkaz:
https://doaj.org/article/5c979793c48a408aa2200abf6493c9e7
Akademický článek
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Autor:
Maryse Cloutier, Bhavesh Variya, Sara Ali Akbari, Fjolla Rexhepi, Subburaj Ilangumaran, Sheela Ramanathan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundInflammatory cytokines play key pathogenic roles in liver fibrosis. IL-15 is a proinflammatory cytokine produced by myeloid cells. IL-15 promotes pathogenesis of several chronic inflammatory diseases. However, increased liver fibrosis has b
Externí odkaz:
https://doaj.org/article/94161557df524f2999654c4125807674
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Vps34 is the unique member of the class III phosphoinositide 3‐kinase family that performs both vesicular transport and autophagy. Its role in natural killer (NK) cells remains uncertain. In this study, a model without Vps34 (Vps34fl/fl/CD
Externí odkaz:
https://doaj.org/article/7089424c9bfb4681b7b4a10bded25ba4
Autor:
André J. Esgalhado, Débora Reste-Ferreira, Sandra Weinhold, Markus Uhrberg, Elsa M. Cardoso, Fernando A. Arosa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Antigen-driven human effector-memory CD8+ T cells expressing low levels of the CD8β chain have been previously described. However, little is known on a possible antigen-independent trigger. We have examined the impact that IL-15 has on the expressio
Externí odkaz:
https://doaj.org/article/31648930f44d470cb930c5352a0605ab
Autor:
Austin T.K. Hoke, Yoko Takahashi, Michelle R. Padget, Javier Gomez, Moran Amit, Jared Burks, Diana Bell, Tongxin Xie, Patrick Soon-Shiong, James W. Hodge, Ehab Y. Hanna, Nyall R. London, Jr
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101943- (2024)
Purpose: Sinonasal undifferentiated carcinoma (SNUC) is a rare, aggressive malignancy of the sinonasal cavity with poor prognosis and limited treatment options. To investigate the potential for SNUC sensitivity to combinatory immunotherapy, we perfor
Externí odkaz:
https://doaj.org/article/21390839f1884ba499e36505b6266d78
Autor:
Di Wu, Anna Cline-Smith, Brady Chrisler, Brittani Lubeck, Ajit Perla, Sumona Banerjee, Ida Fan, Rajeev Aurora
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3289 (2024)
Objective: Milk production during lactation places a high demand for calcium that is fulfilled both from maternal bone resorption and diet. While it is known that mammary gland-derived PTHrP drives bone resorption during lactation, the impact of post
Externí odkaz:
https://doaj.org/article/48becc190573429ab9ebdbbcf610ba01
Autor:
Chun-Ling Liang, Yu-Yan Wei, Yi Chen, Yini Luo, Fenglian Qin, Yuchao Chen, Huazhen Liu, Feifei Qiu, Junbiao Wu, Bin Yang, Yuntao Liu, Zhenhua Dai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116597- (2024)
Zhen-Wu-Tang (ZWT), a conventional herbal mixture, has been recommended for treating lupus nephritis (LN) in clinic. However, its mechanisms of action remain unknown. Here we aimed to define the immunological mechanisms underlying the effects of ZWT
Externí odkaz:
https://doaj.org/article/69e99016617c42dabdb9ea34c6ab223e