Zobrazeno 1 - 10
of 3 134
pro vyhledávání: '"IL‐7"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Messenger RNA (mRNA) vaccines are a key technology in combating existing and emerging infectious diseases. However, improving the immunogenicity and durability of mRNA vaccines remains a challenge. To elicit optimal immune responses, integra
Externí odkaz:
https://doaj.org/article/a0bb94a0b6834b228556ac4471b1f7e8
Autor:
Chaoting Zhang, Ting Liu, Shance Li, Xia Teng, Yuge Zhu, Guanyu Zhang, Huimin Xie, Kang Sun, Jiaxin Tu, Wenjun Yang, Zheming Lu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-6 (2024)
Abstract Enhancing the efficacy of CD19 CAR-T cell therapy can significantly improve patient outcomes by reducing relapse rates in CD19 + B cell malignancies. Exogenous or transgenic cytokines are often used to boost the expansion and durability of C
Externí odkaz:
https://doaj.org/article/83f839168cd84edbb25365849d15419f
Autor:
Gholamreza Azizi, Bram Van den Broek, Larissa Lumi Watanabe Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background The IL-7 receptor alpha (IL-7Rα) binds both IL-7 and thymic stromal lymphopoietin (TSLP). IL-7Rα is essential for the development and survival of naive CD4+ T cells and their differentiation to effector/memory CD4+ T cells. Mice
Externí odkaz:
https://doaj.org/article/846668fffe0b4fe28d72c1b46acd5f96
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1093-1098 (2024)
Psoriatic arthritis (PsA) is a chronic immune-mediated inflammatory joint disease, often associated with psoriasis. Interactions between immune cells, mainly T lymphocytes, and cells of the osteoarticular system are central in the pathogenesis of PsA
Externí odkaz:
https://doaj.org/article/8406f7404fb04e4d8d75d1a0cc36ae6d
Autor:
Reza Yazdani, Mozhde Askari, Amir Moghadam Ahmadi, Gholamreza Azizi, Bogoljub Ciric, Alexandra Boehm, Guang-Xian Zhang, Abdolmohamad Rostami
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The essential role of interleukin 7 (IL-7) signaling via its receptor (IL-7Rα; CD127) in T cell development and function has been well documented. However, CD127 expression and function in myeloid cells, including monocytes, are less clear, especial
Externí odkaz:
https://doaj.org/article/31229c9f1ad6485db018cffdd4e169c2
Autor:
Di WU, Chenhui LI, Yan WANG, Zhengqiang HE, Chang’e JIN, Min GUO, Rongchang CHEN, Chengzhi ZHOU
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 7, Pp 504-513 (2024)
Background and objective Neoantigen reactive T cell (NRT) has the ability to inhibit the growth of tumors expressing specific neoantigens. However, due to the difficult immune infiltration and the inhibition of tumor microenvironment, the therapeutic
Externí odkaz:
https://doaj.org/article/99d0ae41208a49e18fc45411d6005f47
Autor:
Zetao Liu, Zhiyu Peng, Huahang Lin, Ke Zhou, Linchuan Liang, Jie Cao, Zhaokang Huang, Jiandong Mei
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic interstitial lung disease characterized by progressive dyspnea and decreased lung function, yet its exact etiology remains unclear. It is of great significance to discover
Externí odkaz:
https://doaj.org/article/2c6a60b80d8b420f9e3da5d2676486ae
Akademický článek
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Autor:
Xinhui Hui, Muhammad Asad Farooq, Yiran Chen, Iqra Ajmal, Yaojun Ren, Min Xue, Yuzhou Ji, Bingtan Du, Shijia Wu, Wenzheng Jiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSolid tumors are characterized by a low blood supply, complex stromal architecture, and immunosuppressive milieu, which inhibit CAR-T cell entry and survival. CXCR5 has previously been employed to increase CAR-T cell infiltration into CXCL1
Externí odkaz:
https://doaj.org/article/c1ad2c7fde4e490fb662a3877acf229a
Autor:
Shima Shahbaz, Eliana Perez Rosero, Hussain Syed, Mark Hnatiuk, Najmeh Bozorgmehr, Amirhossein Rahmati, Sameera Zia, Jason Plemel, Mohammed Osman, Shokrollah Elahi
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Hematopoiesis is a tightly regulated process that gets skewed toward myelopoiesis. This restrains lymphopoiesis, but the role of lymphocytes in this process is not well defined. To unravel the intricacies of neutrophil responses in COVID-19,
Externí odkaz:
https://doaj.org/article/9a1be3b74be64450aad5c463cb309fd6