Zobrazeno 1 - 10
of 732
pro vyhledávání: '"IKKβ"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 2693-2712 (2024)
Yang Zhao,1,* Yi-Han Wang,2,* Wei-Chao Tu,1 Da-Wei Wang,1 Mu-Jun Lu,3,4 Yuan Shao1 1Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, 201800, People’s Republic of China; 2Departme
Externí odkaz:
https://doaj.org/article/ed93b4774ef94ce9b5493b32dcf9713b
Autor:
Tao Wang, Rui Luo, Jing Zhang, Jing Lan, Zhanhao Lu, Huanjie Zhai, Lian-Feng Li, Yuan Sun, Hua-Ji Qiu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTAfrican swine fever (ASF) is a highly contagious, often fatal viral disease caused by African swine fever virus (ASFV), which imposes a substantial economic burden on the global pig industry. When screening for the virus replication-regulatin
Externí odkaz:
https://doaj.org/article/5003822f8aa54254a9352f99d7a61cfb
Autor:
Molly McKenzie, Guang-Yu Lian, Kathryn A.F. Pennel, Jean A. Quinn, Nigel B. Jamieson, Joanne Edwards
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32904- (2024)
The NFκB pathway, known as the central regulator of inflammation, has a well-established role in colorectal cancer (CRC) initiation, progression, and therapy resistance. Due to the pathway's overarching roles in CRC, there have been efforts to chara
Externí odkaz:
https://doaj.org/article/69cded1c50c04455bef37af3ffae8ba0
Autor:
Miao Lv, Simin Guo, Hexian Yang, Yongjian Wang, Yiming Li, Yang Li, Hong Yi, Hongwei He, Zhuorong Li
Publikováno v:
Molecules, Vol 29, Iss 19, p 4774 (2024)
Liver fibrosis plays an important role in the progression of liver disease, but there is a severe shortage of direct and efficacious pharmaceutical clinical interventions. Literature research indicates that aspartic acid exhibits hepatoprotective pro
Externí odkaz:
https://doaj.org/article/40f5a910905b4177925324dbdaf5babe
Publikováno v:
Viruses, Vol 16, Iss 6, p 949 (2024)
African swine fever (ASF) is an acute, hemorrhagic, highly contagious disease in pigs caused by African swine fever virus (ASFV). Our previous study identified that the ASFV MGF300-2R protein functions as a virulence factor and found that MGF300-2R d
Externí odkaz:
https://doaj.org/article/72fa1fd21ed74661b7c1ae726c1daa4c
Autor:
Zhuqi Huang, Sirui Shen, Xue Han, Weixin Li, Wu Luo, Liming Lin, Mingjiang Xu, Yi Wang, Weijian Huang, Gaojun Wu, Guang Liang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-15 (2023)
Abstract Atherosclerosis is a chronic inflammatory disease with high morbidity and mortality rates worldwide. Doublecortin‐like kinase 1 (DCLK1), a microtubule‐associated protein kinase, is involved in neurogenesis and human cancers. However, the
Externí odkaz:
https://doaj.org/article/77588e6d0d2c4f83a5fb111b485a11b3
Autor:
Jiali Gan, Lin Guo, Xiaolu Zhang, Qun Yu, Qiuyue Yang, Yilin Zhang, Wenyun Zeng, Xijuan Jiang, Maojuan Guo
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Chronic low-grade inflammation has been identified as a major contributor in the development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription factors family of the inflammatory pathway. As a major catalytic su
Externí odkaz:
https://doaj.org/article/b3b932f0404742ae80ad744acf644ed0
Autor:
Yilin Li, Tao Jin, Naixin Liu, Junsong Wang, Zihan Qin, Saige Yin, Yingxuan Zhang, Zhe Fu, Yutong Wu, Yinglei Wang, Yixiang Liu, Meifeng Yang, Ailan Pang, Jun Sun, Ying Wang, Xinwang Yang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Background Despite considerable efforts, ischemic stroke (IS) remains a challenging clinical problem. Therefore, the discovery of effective therapeutic and targeted drugs based on the underlying molecular mechanism is crucial for effective I
Externí odkaz:
https://doaj.org/article/ef4ab64693a743cb8661658d6670308c
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Akademický článek
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