Zobrazeno 1 - 10
of 948
pro vyhledávání: '"IICHIRO SHIMOMURA"'
Autor:
Kei Fujikawa Shingu, Masako Waguri, Mitsuyoshi Takahara, Aurélie Piedvache, Naoto Katakami, Iichiro Shimomura
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 7, Pp 906-913 (2024)
ABSTRACT Aims/Introduction In 2021, the guidelines on gestational weight gain (GWG) were revised and increased by 2–3 kg in Japan. This study aimed to investigate whether the revised guidelines would increase the incidence of babies with excessive
Externí odkaz:
https://doaj.org/article/a051f4b2375f46a49f69390c14742b0e
Autor:
Tasuku Imada, Naoto Katakami, Hirotaka Watanabe, Shuhei Nishina, Shugo Sasaki, Mitsuyoshi Takahara, Iichiro Shimomura, Tsunehiko Yamamoto
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 7, Pp 843-850 (2024)
ABSTRACT Aims/Introduction We aimed to evaluate factors that influence changes in blood low‐density lipoprotein cholesterol (LDL‐C) levels after treatment with sodium–glucose cotransporter 2 (SGLT2) inhibitors in Japanese patients with type 2 d
Externí odkaz:
https://doaj.org/article/51c146760f234b7c895706eaf6e39f6b
Publikováno v:
Endocrine Journal, Vol 71, Iss 12, Pp 1097-1101 (2024)
Lipid metabolism includes lipogenesis, lipolysis, and cholesterol metabolism and it exerts a wide range of biological effects. We previously found novel roles of adipocyte oxidative stress in diet-induced obesity, adipocyte glucocorticoid receptor in
Externí odkaz:
https://doaj.org/article/b3ae6690dc794e12b8c0d9c7d84bde84
Autor:
Saori Motoda, Masanori Kanai, Susumu Sakimoto, Harutoshi Ozawa, Chisaki Ishibashi, Shingo Fujita, Yoshiya Hosokawa, Megu Y. Baden, Yukari Fujita, Takekazu Kimura, Ayumi Tokunaga, Takao Nammo, Kenji Fukui, Junji Kozawa, Hirokazu Sakaguchi, Kohji Nishida, Iichiro Shimomura
Publikováno v:
Endocrine Journal, Vol 71, Iss 10, Pp 965-971 (2024)
We previously reported that a high HbA1c level 3 months before vitrectomy for vitreous hemorrhage or a large preoperative decrease in the HbA1c level over 3 months tended to increase the risk of rebleeding in diabetic retinopathy patients evaluated b
Externí odkaz:
https://doaj.org/article/f389620ab09b46bbad0bc6c149bb52a4
Autor:
Ryohei Mineo, Shiro Fukuda, Shigehito Suzuki, Yoshito Ito, Sachiko Tamba, Takuya Sugiyama, Yuya Fujishima, Hitoshi Nishizawa, Iichiro Shimomura, Koji Yamamoto, Yuji Matsuzawa
Publikováno v:
Endocrine Journal, Vol 71, Iss 7, Pp 705-711 (2024)
At the beginning of 2020, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to epidemics worldwide. Obesity and visceral fat accumulation have been reported to be independent risk factors f
Externí odkaz:
https://doaj.org/article/19dcc408f73c4238b091b180ca2abbaa
Autor:
Eriko Nakano, Kosuke Mukai, Atsunori Fukuhara, Michio Otsuki, Iichiro Shimomura, Takamasa Ichijo, Mika Tsuiki, Norio Wada, Takashi Yoneda, Yoshiyu Takeda, Kenji Oki, Tetsuya Yamada, Yoshihiro Ogawa, Daisuke Yabe, Miki Kakutani, Masakatsu Sone, Takuyuki Katabami, Akiyo Tanabe, Mitsuhide Naruse, JPAS/JRAS Study Group
Publikováno v:
Endocrine Journal, Vol 71, Iss 5, Pp 489-497 (2024)
Aldosterone secretion in primary aldosteronism (PA) is often regulated by adrenocorticotropic hormone (ACTH) in addition to its autonomous secretion. However, the clinical characteristics and risk of cardiovascular and cerebrovascular (CCV) events in
Externí odkaz:
https://doaj.org/article/2a15feaf300c4695a06f7ae103b3b6c6
Autor:
Kohei Fujii, Yuya Fujishima, Shunbun Kita, Keitaro Kawada, Keita Fukuoka, Taka-aki Sakaue, Tomonori Okita, Emi Kawada-Horitani, Hirofumi Nagao, Shiro Fukuda, Norikazu Maeda, Hitoshi Nishizawa, Iichiro Shimomura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Pharmacological activation of hypoxia-inducible factor 1 (HIF-1), a hypoxia-responsive transcription factor, has attracted increasing attention due to its efficacy not only in renal anemia but also in various disease models. Our study demons
Externí odkaz:
https://doaj.org/article/46fee8e55cb540909f4d3fdcc2997904
Definition, criteria, and core concepts of guidelines for the management of obesity disease in Japan
Autor:
Wataru Ogawa, Yushi Hirota, Shigeru Miyazaki, Tadashi Nakamura, Yoshihiro Ogawa, Iichiro Shimomura, Toshimasa Yamauchi, Koutaro Yokote, on behalf of the Creation Committee for Guidelines for the Management of Obesity Disease 2022 by Japan Society for the Study of Obesity (JASSO)
Publikováno v:
Endocrine Journal, Vol 71, Iss 3, Pp 223-231 (2023)
To identify those who might benefit from weight reduction within a large population of obese individuals, Japan Society for the Study of Obesity (JASSO) advocated the concept of “obesity disease.” Here we summarize the definition, criteria, and c
Externí odkaz:
https://doaj.org/article/bc07feec861241f3863052cdbc3c8874
Autor:
Hirofumi Nagao, Hitoshi Nishizawa, Shiro Fukuda, Yuya Fujishima, Shunbun Kita, Norikazu Maeda, Takeshi Bamba, Eiichiro Fukusaki, Iichiro Shimomura
Publikováno v:
Endocrine Journal, Vol 71, Iss 1, Pp 55-63 (2023)
Visceral fat accumulation is a major determinant of type 2 diabetes mellitus and cardiovascular diseases. Recent studies have reported that glutamate is the most elevated amino acid in the plasma amino acid profile in patients with obesity and/or vis
Externí odkaz:
https://doaj.org/article/670f539035a64943b42be14ab1842a95
Autor:
Jihoon Shin, Shinichiro Toyoda, Yosuke Okuno, Reiko Hayashi, Shigeki Nishitani, Toshiharu Onodera, Haruyo Sakamoto, Shinya Ito, Sachiko Kobayashi, Hirofumi Nagao, Shunbun Kita, Michio Otsuki, Atsunori Fukuhara, Kazuhiro Nagata, Iichiro Shimomura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Adiposity varies among individuals with the influence of diverse physiological, pathological, environmental, hormonal, and genetic factors, but a unified molecular basis remains elusive. Here, we identify HSP47, a collagen-specific chaperone
Externí odkaz:
https://doaj.org/article/0b6269b282184cd7a12a5062591aad30