Zobrazeno 1 - 10
of 450
pro vyhledávání: '"IGFBP2"'
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 209-49 (2024)
Insulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in tumor tissues of several malignancies, including pancreatic cancer. Because of its role in tumor progression, IGFBP2 has been investigated as a tumor biomarker. However, little
Externí odkaz:
https://doaj.org/article/a1531f2adc244ad19f984a51de05573c
Autor:
Zhangyi Wu, Nan Wei
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background HOTAIRM1 is revealed to facilitate the malignant progression of glioma. Vasculogenic mimicry (VM) is critically involved in glioma progression. Nevertheless, the molecular mechanism of HOTAIRM1 in regulating glioma VM formation re
Externí odkaz:
https://doaj.org/article/fcf851dbcb51479897b522dc210471a9
Autor:
Xiu Chen, Yu Zhang, Pingping Zhang, Mengzhu Wei, Tian Tian, Yanling Guan, Chenchen Han, Wei Wei, Yang Ma
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive. Herein, we present ev
Externí odkaz:
https://doaj.org/article/370f299d226241e19bbc635b95e6b5fa
Autor:
Li Ji, Ziying Jiao, Lin Zhang, Jia Shi, Qianqian Wan, Chunzhi Qian, Han Wang, Xiaoyan Cao, Bing Shen, Lijuan Jiang
Publikováno v:
Physiological Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Recurrent spontaneous abortion (RSA) is a serious condition that adversely affects women's health. Differentially expressed proteins (DEPs) in plasma of patients experiencing RSA is helpful to find new therapeutic targets and identified with
Externí odkaz:
https://doaj.org/article/afacc76573394c3692902e2648c348fb
Autor:
Wei Yu, Hongli Gao, Tianyang Hu, Xingling Tan, Yiheng Liu, Hongli Liu, Siming He, Zijun Chen, Sheng Guo, Jing Huang
Publikováno v:
Hereditas, Vol 160, Iss 1, Pp 1-14 (2023)
Abstract Background RNA modifications, especially N6-methyladenosine, N1-methyladenosine and 5–methylcytosine, play an important role in the progression of cardiovascular disease. However, its regulatory function in dilated cardiomyopathy (DCM) rem
Externí odkaz:
https://doaj.org/article/ed3ae532ea0747e98b128631e32fdcce
Autor:
Zhaowei Wen, Huiying Sun, Zhihua Zhang, Yannan Zheng, Siting Zheng, Jianping Bin, Yulin Liao, Min Shi, Rui Zhou, Wangjun Liao
Publikováno v:
Cancer Communications, Vol 43, Iss 5, Pp 562-581 (2023)
Abstract Background Several clinical studies have uncovered a negative correlation between baseline tumor burden and the efficacy of immune checkpoint inhibitor (ICI) treatment. This study aimed to uncover the specific mechanisms underlying the diffe
Externí odkaz:
https://doaj.org/article/4e62ff3e3fd3490e8039f94684bb917e
Autor:
Qisheng Luo, Junhong Zhuang, Dandan Zheng, Changfeng Miao, Hongcheng Luo, Jun Peng, Chuanhua Zheng, Chengjian Qin, Chuanliu Lan, Meiqin Chen, Ying Xia, Deyou Huang, Zigui Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCopper metabolism encompasses all cellular metabolic processes involving copper ions and plays a significant role in the pathogenesis of diseases, including cancer. Furthermore, copper is intricately involved in various processes related
Externí odkaz:
https://doaj.org/article/373b3102851b4403a0a7cfb23d3fcea5
Sheep IGFBP2 and IGFBP4 promoter methylation regulates gene expression and hair follicle development
Autor:
Yuezhen Tian, Jianwen Du, Xuemei Yang, Weidan Zeng, Junmin He, Bingru Zhao, Xuefeng Fu, Xinming Xu, Weiwei Wu, Jiang Di, Xixia Huang, Kechuan Tian
Publikováno v:
Electronic Journal of Biotechnology, Vol 59, Iss , Pp 46-54 (2022)
Background: Hair follicle development is important for the fineness of wool. Our previous methylated DNA immunoprecipitation sequencing showed that IGFBP2 and IGFBP4 were differentially methylated at different development stages of the hair follicle
Externí odkaz:
https://doaj.org/article/4c44e18be6b045acaed5bbda3099a885
Publikováno v:
Cancer Medicine, Vol 11, Iss 16, Pp 3035-3047 (2022)
Abstract Background The prognostic significance of insulin‐like growth factor binding protein 2 (IGFBP2) expression has been explored in plenty of studies in human cancers. Because of the controversial results, the meta‐analysis was carried out t
Externí odkaz:
https://doaj.org/article/e7a8c6a219db43a5a37c977f2a9f573c
Autor:
Dae-Hyun Lee, Hyeri Park, Jun-Hyeong You, Jin Seok, Dong-Wook Kwon, Young-Ran Kim, Gi-Jin Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16531 (2023)
The insulin resistance caused by impaired glucose metabolism induces ovarian dysfunction due to the central importance of glucose as a source of energy. However, the research on glucose metabolism in the ovaries is still lacking. The objectives of th
Externí odkaz:
https://doaj.org/article/0a9188712c6a4f208f61dc9acc0e68c7