Zobrazeno 1 - 10
of 621
pro vyhledávání: '"IGF2BP3"'
Autor:
Weiwei Jin, Yanru Yao, Yuhan Fu, Xiangxiang Lei, Wen Fu, Qiliang Lu, Xiangmin Tong, Qiuran Xu, Wei Su, Xiaoge Hu
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background Pancreatic cancer (PC) is one of the most malignant cancers with highly aggressiveness and poor prognosis. N6-methyladenosine (m6A) have been indicated to be involved in PC development. Glucan Branching Enzyme 1 (GBE1) is mainly i
Externí odkaz:
https://doaj.org/article/a2d27816299a41f2973c831644c8b685
Publikováno v:
Thoracic Cancer, Vol 15, Iss 17, Pp 1357-1368 (2024)
Abstract Background Berberine (BBR), an isoquinoline alkaloid from Coptidis rhizoma, has been found to have powerful activities against various human malignancies, including breast cancer. However, the underlying antitumor mechanisms of BBR in breast
Externí odkaz:
https://doaj.org/article/53cf59590ce148e0ba67fc2e510f9f6f
Autor:
Yiran Liang, Fangzhou Ye, Dan Luo, Li Long, Yajie Wang, Yuhan Jin, Lei Wang, Yaming Li, Dianwen Han, Bing Chen, Wenjing Zhao, Lijuan Wang, Qifeng Yang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Breast cancer is the most common malignant tumor, and metastasis remains the major cause of poor prognosis. Glucose metabolic reprogramming is one of the prominent hallmarks in cancer, providing nutrients and energy to support dra
Externí odkaz:
https://doaj.org/article/fc63608af2e64d58b78a06ba25284c7a
Autor:
Honglin Wang, Yingying Cao, Yanling Gou, Hao Wang, Zongwen Liang, Qiong Wu, Jiahuan Tan, Jinming Liu, Zhi Li, Jing Cui, Huiyan Zhang, Zongfeng Zhang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) has been implicated in numerous inflammatory and cancerous conditions. However, its precise molecular mechanisms in endometriosis (EMs) remains unclear. The aim of thi
Externí odkaz:
https://doaj.org/article/a6786da7af604a69863f85de55ff2319
Autor:
Xinmiao Li, Yifei Li, Weizhi Zhang, Feng Jiang, Lifan Lin, Yining Wang, Lingling Wu, Han Zeng, Jianjian Zheng
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
ABSTRACT Introduction Liver fibrosis is primarily driven by the activation of hepatic stellate cells (HSCs), which involves various epigenetic modifications. Objectives N6‐methyladenosine (m6A), the most prevalent RNA modification in eukaryotic cel
Externí odkaz:
https://doaj.org/article/c83d0cab21084294b8e5739e79df0388
Autor:
Lei Lv, Qinqin Wei, Jianxiao Zhang, Yitong Dong, Zhenglei Shan, Na Chang, Ye Zhao, Po Bian, Qiyi Yi
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-29 (2024)
Abstract Background IGF2BP3 functions as an RNA-binding protein (RBP) and plays a role in the posttranscriptional control of mRNA localization, stability, and translation. Its dysregulation is frequently associated with tumorigenesis across various c
Externí odkaz:
https://doaj.org/article/c4b32e0e3e7b48c7a6d69d53309afc5c
Autor:
Dandan Song, Xiaofeng Dai, Minna Fu, Yang Sun, Xingwen Wu, Qianrong Zhou, Wei Bi, Jian Sun, Fei Yang, Youcheng Yu
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101932- (2024)
The genome of oral squamous cell carcinoma (OSCC) has been extensively characterized via bulk sequencing, revealing a multitude of genetic changes. The gene IGF2BP3, which encodes for the insulin-like growth factor 2 mRNA-binding protein 3, has been
Externí odkaz:
https://doaj.org/article/f4ea4565dc72454ea3675d989e01301a
Autor:
Peng Xu, Da-xiong Feng, Jun Wang, Yao-Dong Wang, Gang Xie, Bin Zhang, Xiao-Han Li, Jia-Wei Zeng, Jia-Fu Feng
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Increasing evidence highlights the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the mechanism of AGAP2-AS1 in the occurrence and development of clear
Externí odkaz:
https://doaj.org/article/d889aba166f84b748f3f05af4a84e81d
Autor:
Feifei Yang, Qiang Ma, Bo Huang, Xiaolin Wang, Xiaojuan Pan, Ting Yu, Lingyu Ran, Shan Jiang, Haiping Li, Ye Chen, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Wei Li, Bin Xiao
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA binding protein with multiple roles in regulation of gene expression at the post-transcriptional level and is implicated in tumorigenesis and progression of
Externí odkaz:
https://doaj.org/article/5aa1e929f50845288c399768a9eb7c02
Autor:
Yuheng Lu, Hongbo Zhang, Haoyan Pan, Zhicheng Zhang, Hua Zeng, Haoyu Xie, Jianbin Yin, Wen Tang, Rengui Lin, Chun Zeng, Daozhang Cai
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Disruption of N6 methyl adenosine (m6A) modulation hampers gene expression and cellular functions, leading to various illnesses. However, the role of m6A modification in osteoarthritis (OA) synovitis remains unclear. This study ai
Externí odkaz:
https://doaj.org/article/136f3d3217fa4443b9f44dfd8cd3e98f