IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome

Autor: Araya, Paula, Kinning, Kohl T., Coughlan, Christina, Smith, Keith P., Granrath, Ross E., Enriquez-Estrada, Belinda A., Worek, Kayleigh, Sullivan, Kelly D., Rachubinski, Angela L., Wolter-Warmerdam, Kristine, Hickey, Francis, Galbraith, Matthew D., Potter, Huntington, Espinosa, Joaquin M.

Publikováno v: In Cell Reports 27 December 2022 41(13)

Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish

Autor: Ningmei Zeng, Jiankang Bao, TingTing Shu, Chuang Shi, Gang Zhai, Xia Jin, Jiangyan He, Qiyong Lou, Zhan Yin

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Insulin-like growth factor 1 (IGF1) is an essential effector of the growth hormone (GH)/IGF1 axis for somatic growth regulation in mammals. However, its functions have not been thoroughly investigated in zebrafish in vivo. In this study, the igf1-def

Externí odkaz: https://doaj.org/article/7b574afff5a5480298c9199a49cdf417

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Severe primary IGF1 deficiency diagnosedby a standardized IGF1/ IGFBP3 generation test:The Belgian experience

Autor: Ryckx, Sofie, Derycke, Christine, Anckaert, Ellen, Beauloye, Veronique, Beckers, Dominique, Brachet, Cecile, den Brinker, Marieke, De Waele, Kathleen, Dotremont, Hilde, Boros, Emese, Klink, Daniel, Lebrethon, Marie-Christine, Lysy, Philippe A, Mouraux, Thierry, Parent, Anne-Simone, Rochtus, Anne, van der Straaten, Saskia, De Schepper, Jean

RFC10.2Background/Aim: Over the past 6 years, the IGF1/ IGFBP3generation test (IGFGT) has been used in Belgium in a standardized form to identify children with severe primary IGF1 deficiency(SPIGFD). In this study, the discordance of the IGF1 and IGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3848::f5f31c0f035dcbb6015f643ec18c6799
https://biblio.vub.ac.be/vubir/severe-primary-igf1-deficiency-diagnosedby-a-standardized-igf1-igfbp3-generation-testthe-belgian-experience(8c63eb0c-04b0-4152-8aea-6018e1b27937).html

A homozygous mutation in the highly conserved Tyr60 of the mature IGF1 peptide broadens the spectrum of IGF1 deficiency

Autor: M J E Walenkamp, J.M. Wit

Publikováno v: European Journal of Endocrinology, 181(6), C29-C33. BioScientifica Ltd.
Walenkamp, M J E & Wit, J M 2019, ' A homozygous mutation in the highly conserved Tyr60 of the mature IGF1 peptide broadens the spectrum of IGF1 deficiency ', European Journal of Endocrinology, vol. 181, no. 6, pp. C29-C33 . https://doi.org/10.1530/EJE-19-0801
European Journal of Endocrinology, 181(6), C29-C33

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d54764a163ea0f3bcaa389ac9be20f7
https://hdl.handle.net/1887/3195451