Oxidative stress in the eye in diabetes

Autor: Ig Obrosova

Publikováno v: Acta Ophthalmologica. 89

Purpose The characterize manifestations of oxidative stress in lens and retina in diabetes, and to evaluate the roles for aldose reductase (AR), Na+-H+-exchanger-1 (NHE-1), and poly(ADP-ribose) polymerase-1 (PARP-1) in oxidative stress in both tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d50fbbfe529ffbb9490a8db6aea55e95
https://doi.org/10.1111/j.1755-3768.2011.3162.x

Aldose Reductase Inhibition Counteracts Diabetes-Induced Retinal Oxidative Injury, Glial Activation, and Apoptosis

Autor: Vr Drel, Ig Obrosova, Tk Ali, A El-Remezzy, J. Shin, Ulrich Julius

Publikováno v: Acta Ophthalmologica Scandinavica. 85

Purpose: To access the role for increased aldose reductase (AR) activity in oxidative injury, glial activation, and apoptosis in retinae of diabetic rats and high glucose-exposed cultured retinal pericytes and endothelial cells. Methods: Control (C)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::910b3e13153812565181fe569ecaaafc
https://doi.org/10.1111/j.1600-0420.2007.01063_3145.x

Role of Peroxynitrite in the Development of Diabetic Peripheral Neuropathy.

Autor: Edwards JF; Strelitz Diabetes Center and Neuroendocrine Unit, Eastern Virginia Medical School, Norfolk, VA., Casellini CM; Strelitz Diabetes Center and Neuroendocrine Unit, Eastern Virginia Medical School, Norfolk, VA., Parson HK; Strelitz Diabetes Center and Neuroendocrine Unit, Eastern Virginia Medical School, Norfolk, VA., Obrosova IG; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA., Yorek M; Department of Medicine, University of Iowa, and Veterans Affairs Medical Center, Iowa City, IA., Vinik AI; Strelitz Diabetes Center and Neuroendocrine Unit, Eastern Virginia Medical School, Norfolk, VA vinikai@evms.edu.

Publikováno v: Diabetes care [Diabetes Care] 2015 Jul; Vol. 38 (7), pp. e100-1.

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab).

Autor: Biessels GJ; The Working Group of Neurodials., Bril V, Calcutt NA, Cameron NE, Cotter MA, Dobrowsky R, Feldman EL, Fernyhough P, Jakobsen J, Malik RA, Mizisin AP, Oates PJ, Obrosova IG, Pop-Busui R, Russell JW, Sima AA, Stevens MJ, Schmidt RE, Tesfaye S, Veves A, Vinik AI, Wright DE, Yagihashi S, Yorek MA, Ziegler D, Zochodne DW

Publikováno v: Journal of the peripheral nervous system : JPNS [J Peripher Nerv Syst] 2014 Jun; Vol. 19 (2), pp. 77-87.

Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats.

Autor: Lupachyk S; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA., Watcho P, Shevalye H, Vareniuk I, Obrosov A, Obrosova IG, Yorek MA

Publikováno v: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2013 Aug 01; Vol. 305 (3), pp. E396-404. Date of Electronic Publication: 2013 Jun 04.