Zobrazeno 1 - 10
of 75
pro vyhledávání: '"IFRD1"'
Autor:
Morgan W. Mann, Yao Fu, Robert L. Gearhart, Xiaofang Xu, David S. Roberts, Yi Li, Jia Zhou, Ying Ge, Allan R. Brasier
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionBromodomain-containing Protein 4 (BRD4) is a transcriptional regulator which coordinates gene expression programs controlling cancer biology, inflammation, and fibrosis. In the context of airway viral infection, BRD4-specific inhibitors (
Externí odkaz:
https://doaj.org/article/2883b714e680481cbee4ff761684ca8c
Akademický článek
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Akademický článek
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Autor:
Ying-Huang Tsai, Chin-Chou Wang, Shih-Feng Liu, Yu-Ping Chang, Tung-Ying Chao, Yu-Feng Wei, C Lee, Wen-Feng Fang, Po-Yuan Hsu, Chao-Chien Wu, Huang-Chih Chang, Chia-Cheng Tsen, Yung-Che Chen, Meng-Chih Lin, Ting-Wen Chen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
We hypothesized that epigenetics is a link between smoking/allergen exposures and the development of Asthma and chronic obstructive pulmonary disease (ACO). A total of 75 of 228 COPD patients were identified as ACO, which was independently associated
Autor:
Alemayehu Z. Wolde, Wilfried Karmaus, Rutu Patel, Susan Ewart, John W. Holloway, Caroline L Relton, Farnaz Solatikia, Ryan Arathimos, Latha Kadalayil, Hongmei Zhang, Susan M. Ring, Syed Hasan Arshad, A. J. Henderson
Publikováno v:
Clin Exp Allergy
Patel, R, Solatikia, F, Zhang, H, Wolde, A, Kadalayil, L, Karmaus, W, Ewart, S, Arathimos, R S, Relton, C L, Ring, S M, Henderson, A J W, Arshad, S H & Holloway, J 2020, ' Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence ', Clinical and Experimental Allergy, vol. 51, no. 2, pp. 318-328 . https://doi.org/10.1111/cea.13776
Patel, R, Solatikia, F, Zhang, H, Wolde, A, Kadalayil, L, Karmaus, W, Ewart, S, Arathimos, R S, Relton, C L, Ring, S M, Henderson, A J W, Arshad, S H & Holloway, J 2020, ' Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence ', Clinical and Experimental Allergy, vol. 51, no. 2, pp. 318-328 . https://doi.org/10.1111/cea.13776
BackgroundUnderlying biological mechanisms involved in sex differences in asthma status changes from pre‐ to post‐adolescence are unclear. DNA methylation (DNAm) has been shown to be associated with the risk of asthma.ObjectiveWe hypothesized tha
Autor:
Ilja Vietor, Domagoj Cikes, Kati Piironen, Theodora Vasakou, David Heimdörfer, Ronald Gstir, Matthias David Erlacher, Ivan Tancevski, Philipp Eller, Egon Demetz, Michael Hess, Volker Kuhn, Gerald Degenhart, Jan Rozman, Martin Klingenspor, Martin Hrabe de Angelis, Taras Valovka, Lukas A. Huber
Delta-like homolog 1 (DLK1), an inhibitor of adipogenesis, controls the cell fate of adipocyte progenitors. Here we identify two independent regulatory mechanisms, transcriptional and translational, by which TIS7 (IFRD1) and its orthologue SKMc15 (IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e21fb1b6287f83ef33e5d764ded1b50
https://doi.org/10.1101/719922
https://doi.org/10.1101/719922
Publikováno v:
Data in Brief
Data in Brief, Vol 25, Iss, Pp-(2019)
Data in Brief, Vol 25, Iss, Pp-(2019)
The interferon-related developmental regulator 1 (IFRD1) protein is expected to play a role in the regulation of inflammatory responses in adult mice, since it is known to repress transcription of NF-κB in myoblasts that regenerate skeletal muscle a
Autor:
Min Sun, Liying Liu, Siqi Wang, Yuhui Wang, Fang Liu, Wenliang Fan, Ping Han, Chunyuan Cen, Xiaobin Jiang, Hongyang Zhao
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Journal of Translational Medicine
Journal of Translational Medicine
Background Glioblastomas have a high degree of malignancy, high recurrence rate, high mortality rate, and low cure rate. Searching for new markers of glioblastomas is of great significance for improving the diagnosis, prognosis and treatment of gliom
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-33 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-33 (2019)
Background Amyotrophic lateral sclerosis (ALS) is a debilitating disease with few treatment options. Progress towards new therapies requires validated disease biomarkers, but there is no consensus on which fluid-based measures are most informative. M
Autor:
Lo Presti Ar, Alessandro Baldan, Carlo Castellani, Francesca Belpinati, Luciano Xumerle, Cristina Bombieri, Giovanni Malerba, Pignatti Pr, Bettin
Publikováno v:
Rhinology journal. 53:359-364
Background: Nasal polyposis (NP) is an inflammatory disease of the upper nasal airways frequently present in CF patients. Interferon-Related Developmental Regulator 1 (IFRD1) gene was reported as a possible modifier of CF lung disease severity. Three