Zobrazeno 1 - 10
of 16
pro vyhledávání: '"IDL, intermediate density lipoprotein"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 1, Pp 34-50 (2018)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Natural biomacromolecules have attracted increased attention as carriers in biomedicine in recent years because of their inherent biochemical and biophysical properties including renewability, nontoxicity, biocompatibility, biodegradability, long blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7426b5efae73e9c0099c0a65c0e2aa0
http://www.sciencedirect.com/science/article/pii/S2211383517302812
http://www.sciencedirect.com/science/article/pii/S2211383517302812
Autor:
Holmes, Michael V., Millwood, Iona Y., Kartsonaki, Christiana, Hill, Michael R., Bennett, Derrick A., Boxall, Ruth, Guo, Yu, Xu, Xin, Bian, Zheng, Hu, Ruying, Walters, Robin G., Chen, Junshi, Ala-Korpela, Mika, Parish, Sarah, Clarke, Robert J., Peto, Richard, Collins, Rory, Li, Liming, Chen, Zhengming
Publikováno v:
Journal of the American College of Cardiology
Holmes, M V, Millwood, I Y, Kartsonaki, C, Hill, M R, Bennett, D A, Boxall, R, Guo, Y, Xu, X, Bian, Z, Hu, R, Walters, R G, Chen, J, Ala-Korpela, M, Parish, S, Clarke, R J, Peto, R, Collins, R, Li, L & Chen, Z 2018, ' Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke ', Journal of the American College of Cardiology, vol. 71, no. 6, pp. 620-632 . https://doi.org/10.1016/j.jacc.2017.12.006
Holmes, M V, Millwood, I Y, Kartsonaki, C, Hill, M R, Bennett, D A, Boxall, R, Guo, Y, Xu, X, Bian, Z, Hu, R, Walters, R G, Chen, J, Ala-Korpela, M, Parish, S, Clarke, R J, Peto, R, Collins, R, Li, L & Chen, Z 2018, ' Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke ', Journal of the American College of Cardiology, vol. 71, no. 6, pp. 620-632 . https://doi.org/10.1016/j.jacc.2017.12.006
Background Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating metabolites for MI and stroke subtypes. Objectives This study sought t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bfb6c622517bfed147a616199c63a21e
http://europepmc.org/articles/PMC5811927
http://europepmc.org/articles/PMC5811927
Autor:
Nesrin Kartal Ozer, Erdi Sozen
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 456-461 (2017)
Redox Biology
Redox Biology
Endoplasmic reticulum (ER) is the major site of protein folding and calcium storage. Beside the role of ER in protein homeostasis, it controls the cholesterol production and lipid-membrane biosynthesis as well as surviving and cell death signaling me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dea8447e0777531c13dc36c385360b
http://www.sciencedirect.com/science/article/pii/S2213231717300782
http://www.sciencedirect.com/science/article/pii/S2213231717300782
Autor:
C. Cherfils, Laurence Barbot-Trystram, Georges Nouadje, Philippe Giral, Dominique Bonnefont-Rousselot, Randa Bittar, Valérie Fesel-Fouquier, Alain Carrié
Publikováno v:
Practical Laboratory Medicine
Practical Laboratory Medicine, Elsevier, 2020, 18, pp.e00150-. ⟨10.1016/j.plabm.2019.e00150⟩
Practical Laboratory Medicine, 2020, 18, pp.e00150. ⟨10.1016/j.plabm.2019.e00150⟩
Practical Laboratory Medicine, Vol 18, Iss, Pp-(2020)
Practical Laboratory Medicine, Elsevier, 2020, 18, pp.e00150-. ⟨10.1016/j.plabm.2019.e00150⟩
Practical Laboratory Medicine, 2020, 18, pp.e00150. ⟨10.1016/j.plabm.2019.e00150⟩
Practical Laboratory Medicine, Vol 18, Iss, Pp-(2020)
A qualitative, semi-automatized method for apolipoprotein E (apoE) phenotyping by isoelectric focusing method has been evaluated on 40 serum samples from patients previously genotyped for apoE, especially as regards concordance with genotyping, but a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6e94ea6828186e728a0eff66201e6b
https://hal.archives-ouvertes.fr/hal-03489268
https://hal.archives-ouvertes.fr/hal-03489268
Publikováno v:
Redox Biology
Redox Biology, Vol 23, Iss, Pp-(2019)
Redox Biology, Vol 23, Iss, Pp-(2019)
Lipoproteins are essential systemic lipid transport particles, composed of apolipoproteins embedded in a phospholipid and cholesterol monolayer surrounding a cargo of diverse lipid species. Many of the lipids present are susceptible to oxidative dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ccae2f1f360892b58af051df032521
Autor:
Mika Tiainen, George Davey Smith, Veikko Salomaa, Antti J. Kangas, Pasi Soininen, Qin Wang, Pekka Mäntyselkä, Marjo-Riitta Järvelin, Tuulia Tynkkynen, Mika Kähönen, Mika Ala-Korpela, Johannes Kettunen, Markus Perola, Mika Kivimäki, Mauno Vanhala, Peter Würtz, Ghazaleh Fatemifar, Alun D. Hughes, Therese Tillin, Juan-Pablo Casas, Terho Lehtimäki, Aroon D. Hingorani, Nish Chaturvedi, Olli T. Raitakari, Naveed Sattar, Debbie A Lawlor
Publikováno v:
Journal of the American College of Cardiology
Würtz, P, Wang, Q, Soininen, P, Kangas, A J, Fatemifar, G, Tynkkynen, T, Tiainen, M, Perola, M, Tillin, T, Hughes, A D, Mäntyselkä, P, Kähönen, M, Lehtimäki, T, Sattar, N, Hingorani, A D, Casas, J-P, Salomaa, V, Kivimäki, M, Järvelin, M-R, Davey Smith, G, Vanhala, M, Lawlor, D A, Raitakari, O T, Chaturvedi, N, Kettunen, J & Ala-Korpela, M J 2016, ' Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase ', Journal of the American College of Cardiology, vol. 67, no. 10, pp. 1200-1210 . https://doi.org/10.1016/j.jacc.2015.12.060
Würtz, P, Wang, Q, Soininen, P, Kangas, A J, Fatemifar, G, Tynkkynen, T, Tiainen, M, Perola, M, Tillin, T, Hughes, A D, Mäntyselkä, P, Kähönen, M, Lehtimäki, T, Sattar, N, Hingorani, A D, Casas, J-P, Salomaa, V, Kivimäki, M, Järvelin, M-R, Davey Smith, G, Vanhala, M, Lawlor, D A, Raitakari, O T, Chaturvedi, N, Kettunen, J & Ala-Korpela, M J 2016, ' Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase ', Journal of the American College of Cardiology, vol. 67, no. 10, pp. 1200-1210 . https://doi.org/10.1016/j.jacc.2015.12.060
Article
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized. Objectives This study
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized. Objectives This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8762226c1c15ad39329dcef82127257d
https://doi.org/10.1016/j.jacc.2015.12.060
https://doi.org/10.1016/j.jacc.2015.12.060
Autor:
Simon D. Taylor-Robinson, Asmaa Gomaa, Jin Un Kim, Elaine Holmes, Nimzing G. Ladep, Imam Waked, Mary M.E. Crossey, Mohamed I.F. Shariff, I. Jane Cox, Edith N. Okeke, Edmund Banwat, Roger Williams
BACKGROUND/AIMS: Previous studies have observed disturbances in the (1)H nuclear magnetic resonance (NMR) blood spectral profiles in malignancy. No study has metabotyped serum or plasma of hepatocellular carcinoma (HCC) patients from two diverse popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c3f0cc42df3b36fe53de2e5da25974
http://hdl.handle.net/10044/1/49572
http://hdl.handle.net/10044/1/49572
Autor:
Christian Bo Poulsen, Charlotte Brandt Sørensen, Juan Li, Christina Christoffersen, Mette Schmidt, Ying Liu, Lars Bolund, Rong Li, Henrik Callesen, Jacob F. Bentzon, Peter M. H. Heegaard, Jeong Shim, Torben Larsen, Mette K. Hagensen
Publikováno v:
JACC: Basic to Translational Science
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis, but not xanthoma formation, in gene modified minipigs ', J A C C: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to translational science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 591-600 (2017)
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis, but not xanthoma formation, in gene modified minipigs ', J A C C: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to translational science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 591-600 (2017)
Visual Abstract
Highlights • APOE-deficient Yucatan minipigs were created by recombinant adeno-associated virus mediated gene targeting in porcine fibroblasts followed by somatic cell nuclear transfer. • APOE−/− minipigs displayed increa
Highlights • APOE-deficient Yucatan minipigs were created by recombinant adeno-associated virus mediated gene targeting in porcine fibroblasts followed by somatic cell nuclear transfer. • APOE−/− minipigs displayed increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfca117654ccdc1f9a89d6b8fd019f7
https://pubmed.ncbi.nlm.nih.gov/30062172
https://pubmed.ncbi.nlm.nih.gov/30062172
Autor:
Tapani Rönnemaa, Jorma Viikari, Olli T. Raitakari, Pasi Soininen, Hanna Lagström, Antti Jula, Harri Niinikoski, Peter Würtz, Antti J. Kangas, Katja Pahkala, Mika Ala-Korpela, Miia Lehtovirta
Publikováno v:
Lehtovirta, M, Pahkala, K, Niinikoski, H, Kangas, A J, Soininen, P, Lagström, H, Viikari, J S A, Rönnemaa, T, Jula, A, Ala-Korpela, M, Würtz, P & Raitakari, O T 2018, ' Effect of Dietary Counseling on a Comprehensive Metabolic Profile from Childhood to Adulthood ', Journal of Pediatrics, vol. 195, pp. 190-198.e3 . https://doi.org/10.1016/j.jpeds.2017.11.057
The Journal of Pediatrics
The Journal of Pediatrics
Objectives: To study the effects of repeated, infancy-onset dietary counseling on a detailed metabolic profile. Effects of dietary saturated fat replacement on circulating concentrations of metabolic biomarkers still remain unknown. Study design: The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc880bd15d76926063a7b651015ded37
https://doi.org/10.1016/j.jpeds.2017.11.057
https://doi.org/10.1016/j.jpeds.2017.11.057
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