Zobrazeno 1 - 10
of 378
pro vyhledávání: '"IDH-mutant"'
Autor:
Renzhi Deng, Jianying Qin, Lei Wang, Haibin Li, Ning Wen, Ke Qin, Jianhui Dong, Jihua Wu, Dandan Zhu, Xuyong Sun
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Glioma is the most common brain tumor. IDH mutations occur frequently in glioma, indicating a more favorable prognosis. We aimed to explore energy metabolism-related genes in glioma to promote the research and treatment. Methods D
Externí odkaz:
https://doaj.org/article/36d58dcd4196404d9e85a12a7f61b1f4
Autor:
Olga Kim, Zach Sergi, Guangyang Yu, Kazutoshi Yamamoto, Martha Quezado, Zied Abdullaev, Danel R. Crooks, Shun Kishimoto, Qi Li, Peng Lu, Burchelle Blackman, Thorkell Andresson, Xiaolin Wu, Bao Tran, Jun S. Wei, Wei Zhang, Meili Zhang, Hua Song, Javed Khan, Murali C. Krishna, Jeffrey R. Brender, Jing Wu
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Malignant transformation (MT) is commonly seen in IDH-mutant gliomas. There has been a growing research interest in revealing its underlying mechanisms and intervening prior to MT at the early stages of the transforming process. Here we esta
Externí odkaz:
https://doaj.org/article/4b329e13fa87456ea2628bbe4d0bfe40
Autor:
CAO Yujuan, YAO Xiaohong
Publikováno v:
陆军军医大学学报, Vol 46, Iss 12, Pp 1441-1446 (2024)
Objective To analyze the clinical features and magnetic resonance imaging (MRI) features of adult diffuse glioma, define the preoperative MRI enhancement grade (ET grade) of the disease, and explore the relationship of ET grade with isocitrate dehydr
Externí odkaz:
https://doaj.org/article/f7d9858dc1f04e76bdc76274b730541f
Publikováno v:
Indian Journal of Radiology and Imaging, Vol 34, Iss 02, Pp 351-355 (2024)
Isocitrate dehydrogenase mutant gliomas generally have a better prognosis than their wild-type counterpart. Recurrences are generally within the radiation field in the primary tumoral bed. Remote recurrence is uncommon and is usually intraparenchymal
Externí odkaz:
https://doaj.org/article/e372d67a5293497f9305cd718bda8b80
Autor:
Wenlin Chen, Siying Guo, Yaning Wang, Yixin Shi, Xiaopeng Guo, Delin Liu, Yilin Li, Yuekun Wang, Hao Xing, Yu Xia, Junlin Li, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18666-18678 (2023)
Abstract Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4. However, the underst
Externí odkaz:
https://doaj.org/article/b696f3ea363c4d48ac7e65f7d26c2e42
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Joe Q. Wei, Michael Rodriguez, Michael Back, Nick Pavlakis, Amanda Hudson, Marina Kastelan, Helen R. Wheeler, Adrian Lee
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5276-5292 (2023)
Genomic alterations of CDKN2A and CDKN2B in astrocytomas have been an evolving area of study for decades. Most recently, there has been considerable interest in the effect of CDKN2A and/or CDKN2B (CDKN2A/B) homozygous deletions (HD) on the prognosis
Externí odkaz:
https://doaj.org/article/cd5e480404154d849fb4a23f59390562
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn 2021, the World Health Organization published a new classification system for central nervous system tumors. This study reclassified the adult diffuse glioma (ADG) into astrocytoma, oligodendroglioma, and glioblastoma (GBM) according t
Externí odkaz:
https://doaj.org/article/9b7500e74a324ec59816b44d9f14d9c5
Autor:
Sandra Ferreyra Vega, Thomas Olsson Bontell, Teresia Kling, Asgeir Store Jakola, Helena Carén
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Diffuse gliomas are the most prevalent malignant primary brain tumors in adults and remain incurable despite standard therapy. Tumor recurrence is currently inevitable, which contributes to a persistent high morbidity and mortality in these
Externí odkaz:
https://doaj.org/article/b2c3c4bc057643f99422e07e4d0768af
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