Zobrazeno 1 - 10
of 419
pro vyhledávání: '"IDH mutant glioblastomas"'
Autor:
Korshunov, A.1,2, Casalini, B.1, Chavez, L.2,3,4, Hielscher, T.5, Sill, M.2,3,4, Ryzhova, M.6, Sharma, T.2,3,4, Schrimpf, D.1, Stichel, D.1, Capper, D.7,8,9, Reuss, D. E.1, Sturm, D.2,3,4,10, Absalyamova, O.6, Golanov, A.6, Lambo, S.2,3,4, Bewerunge‐Hudler, M.11, Lichter, P.12, Herold‐Mende, C.13, Wick, W.14,15, Pfister, S. M.2,3,4,10
Publikováno v:
Neuropathology & Applied Neurobiology. Feb2019, Vol. 45 Issue 2, p108-118. 11p.
Akademický článek
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Akademický článek
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Publikováno v:
Carcinogenesis
Isocitrate dehydrogenase (IDH) mutant glioblastoma (GBM), accounts for ~10% GBMs, arises from lower grade diffuse glioma and preferentially appears in younger patients. Here, we aim to establish a robust gene expression-based molecular classification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4e6dd0396f951074e761d63ebd4e6f
https://doi.org/10.1093/carcin/bgz032
https://doi.org/10.1093/carcin/bgz032
Publikováno v:
Neuro Oncol
BACKGROUND IDH-mutant glioblastoma is classified by the 2016 CNS WHO as a group with good prognosis. However, the actual number of cases examined in the literature is relatively small. We hypothesize that IDH-mutant glioblastoma is not a uniform grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d3593347f5cf31d9b6def6c9fdc29a
https://europepmc.org/articles/PMC6796035/
https://europepmc.org/articles/PMC6796035/
Autor:
Johnny S. H. Kwan, Houtan Noushmehr, Aden Ka-Yin Chan, Kay Ka-Wai Li, Ying Mao, Ho Keung Ng, Zhifeng Shi, Hong Chen, Rui Ryan Yang, Tathiane M. Malta, Shaz Cheng, Wai Sang Poon
Publikováno v:
Neuro-Oncology Advances. 1
Background IDH-mutant glioblastoma is classified by the 2016 CNS WHO as a group with good prognosis. However, the actual number of cases examined in the literature is relatively small. We hypothesize that IDH-mutant glioblastoma is not a uniform grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1293fed11ffb44650bb94eb83f26f877
https://doi.org/10.1093/noajnl/vdz015
https://doi.org/10.1093/noajnl/vdz015
Publikováno v:
Neuro Oncol
The number of IDH-mutant glioblastoma examined in the literature and TCGA is few. We used Infinium MethylationEPIC BeadChip array to classify 64 IDH-mutant-GBM into methylation groups. Gene copy number variations were determined from methylation. 53.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47450bd6e467b9dc90c9b1b543557226
https://europepmc.org/articles/PMC6789984/
https://europepmc.org/articles/PMC6789984/
Autor:
Marcel Kool, Melanie Bewerunge-Hudler, Damian Stichel, Sander Lambo, Daniel Schrimpf, A. von Deimling, Tanvi Sharma, Thomas Hielscher, Oksana Absalyamova, Martin Sill, Marina Ryzhova, Felix Sahm, Wolfgang Wick, David E. Reuss, Peter Lichter, Lukas Chavez, Dtw Jones, Belen Casalini, Dominik Sturm, Christel Herold-Mende, David Capper, Andrey Korshunov, S Pfister, Andrey Golanov
Publikováno v:
Neuropathology and applied neurobiology. 45(2)
Aims Mutations of isocitrate dehydrogenase (IDH)1/2 affect almost all astrocytomas of WHO grade II and III. A subset of IDH-mutant astrocytic tumours progresses to IDH-mutant glioblastoma or presents with the histology of a glioblastoma at first pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7a19dabcff6817fc2a75730bdd087a
https://pubmed.ncbi.nlm.nih.gov/30326147
https://pubmed.ncbi.nlm.nih.gov/30326147
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Joe Q. Wei, Michael Rodriguez, Michael Back, Nick Pavlakis, Amanda Hudson, Marina Kastelan, Helen R. Wheeler, Adrian Lee
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5276-5292 (2023)
Genomic alterations of CDKN2A and CDKN2B in astrocytomas have been an evolving area of study for decades. Most recently, there has been considerable interest in the effect of CDKN2A and/or CDKN2B (CDKN2A/B) homozygous deletions (HD) on the prognosis
Externí odkaz:
https://doaj.org/article/cd5e480404154d849fb4a23f59390562
Publikováno v:
Neuro Oncol
IDH-mutant glioblastoma is classified by the 2016 CNS WHO as a group with good prognosis. However, the actual number of cases examined in the literature is relatively small. We hypothesize that IDH-mutant glioblastoma is not a uniform group and shoul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86168fdb3cd412550e47bcb5c4815125
https://doi.org/10.1093/neuonc/noz175.611
https://doi.org/10.1093/neuonc/noz175.611