Zobrazeno 1 - 10
of 78
pro vyhledávání: '"IDH (isocitrate dehydrogenase)"'
Autor:
Josefine Radke, Arend Koch, Fabienne Pritsch, Elisa Schumann, Martin Misch, Claudia Hempt, Klaus Lenz, Franziska Löbel, Fabienne Paschereit, Frank L. Heppner, Peter Vajkoczy, Randi Koll, Julia Onken
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise predictive cutoff values to distinguish “MGMT methylated” from “MGMT unmethylat
Externí odkaz:
https://doaj.org/article/46257491055d467c96bc511dbfbdcba7
Akademický článek
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Autor:
Arpita Sahu, Nandakumar G. Patnam, Jayant Sastri Goda, Sridhar Epari, Ayushi Sahay, Ronny Mathew, Amit Kumar Choudhari, Subhash M. Desai, Archya Dasgupta, Abhishek Chatterjee, Pallavi Pratishad, Prakash Shetty, Ali Asgar Moiyadi, Tejpal Gupta
Publikováno v:
Journal of Personalized Medicine; Volume 13; Issue 1; Pages: 72
Purpose and background: Isocitrate dehydrogenase (IDH) mutation and O-6 methyl guanine methyl transferase (MGMT) methylation are surrogate biomarkers of improved survival in gliomas. This study aims at studying the ability of semantic magnetic resona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddeb6c3527c2357e7d1a1d3b4576bad
Publikováno v:
JACC: Basic to Translational Science
Highlights • Cancer cells can promote metabolic remodeling in the heart. • Metabolic changes provide opportunities for novel treatment strategies to prevent heart failure and monitor disease progression through new imaging techniques. • Transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68748cb7277a02618d388f95ef5a04f2
http://europepmc.org/articles/PMC8385559
http://europepmc.org/articles/PMC8385559
Akademický článek
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Autor:
Niamh C. Williams, Dylan G. Ryan, Ana S.H. Costa, Evanna L. Mills, Mark P. Jedrychowski, Suzanne M. Cloonan, Christian Frezza, Luke A. O'Neill
Publikováno v:
The Journal of Biological Chemistry
Activated macrophages undergo metabolic reprogramming, which not only supports their energetic demands but also allows for the production of specific metabolites that function as signaling molecules. Several Krebs cycles, or Krebs-cycle-derived metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349c95bf1633c1057ab765daa0319a9a
https://pubmed.ncbi.nlm.nih.gov/34929172
https://pubmed.ncbi.nlm.nih.gov/34929172
Autor:
David A. Hanna, Roshan Kumar, Aditi Gupta, Marouane Libiad, Jace W. Jones, Victor Vitvitsky, Ruma Banerjee, Sebastián Carballal
Publikováno v:
The Journal of Biological Chemistry
Mammalian cells synthesize H2S from sulfur-containing amino acids and are also exposed to exogenous sources of this signaling molecule, notably from gut microbes. As an inhibitor of complex IV in the electron transport chain, H2S can have a profound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4126c798519bf53806142328813d474
http://europepmc.org/articles/PMC8342795
http://europepmc.org/articles/PMC8342795
Autor:
Olarte I, García A, Ramos C, Arratia B, Centeno F, Paredes J, Rozen E, Kassack J, Collazo J, Martínez A
Publikováno v:
OncoTargets and Therapy, Vol Volume 12, Pp 8023-8031 (2019)
Irma Olarte,1 Anel García,1 Christian Ramos,2 Brenda Arratia,1 Federico Centeno,3 Johanna Paredes,1 Etta Rozen,2 Juan Kassack,2 Juan Collazo,2 Adolfo Martínez1 1Department of Molecular Biology, Hematology Service, Hospital General de México, “Dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::82ca32679f6556882bbd1252f332ed86
https://www.dovepress.com/detection-of-mutations-in-the-isocitrate-dehydrogenase-genes-idh1idh2--peer-reviewed-article-OTT
https://www.dovepress.com/detection-of-mutations-in-the-isocitrate-dehydrogenase-genes-idh1idh2--peer-reviewed-article-OTT
Autor:
Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han
Publikováno v:
EBioMedicine
Background DNA damage repair (DDR) alterations are important events in cancer initiation, progression, and therapeutic resistance. However, the involvement of DDR alterations in glioma malignancy needs further investigation. This study aims to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae288d30336e455721de6bf5436f314b
https://doi.org/10.1016/j.ebiom.2019.01.067
https://doi.org/10.1016/j.ebiom.2019.01.067
Akademický článek
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