Zobrazeno 1 - 10
of 775
pro vyhledávání: '"ID2"'
Akademický článek
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Autor:
Xiuxing Liu, Chenyang Gu, Jianjie Lv, Qi Jiang, Wen Ding, Zhaohao Huang, Yidan Liu, Yuhan Su, Chun Zhang, Zhuping Xu, Xianggui Wang, Wenru Su
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Autoimmune uveitis (AU) is the most common ophthalmic autoimmune disease (AD) and is characterized by a complex etiology, high morbidity, and high rate of blindness. AU remission has been observed in pregnant female patients. Howe
Externí odkaz:
https://doaj.org/article/237d27220310489b8bb253ac27fe88be
Autor:
Marta Boccazzi, Giulia Macchiarulo, Sophie Lebon, Justyna Janowska, Tifenn Le Charpentier, Valérie Faivre, Jennifer Hua, Davide Marangon, Davide Lecca, Marta Fumagalli, Shyamala Mani, Maria P. Abbracchio, Pierre Gressens, Anne-Laure Schang, Juliette Van Steenwinckel
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106315- (2023)
G protein-coupled receptor 17 (GPR17) and the WNT pathway are critical players of oligodendrocyte (OL) differentiation acting as essential timers in developing brain to achieve fully-myelinating cells. However, whether and how these two systems are r
Externí odkaz:
https://doaj.org/article/5762b6f592454653a1582747d57ba39b
Autor:
Robert Machold, Shlomo Dellal, Manuel Valero, Hector Zurita, Ilya Kruglikov, John Hongyu Meng, Jessica L Hanson, Yoshiko Hashikawa, Benjamin Schuman, György Buzsáki, Bernardo Rudy
Publikováno v:
eLife, Vol 12 (2023)
Cortical GABAergic interneurons (INs) represent a diverse population of mainly locally projecting cells that provide specialized forms of inhibition to pyramidal neurons and other INs. Most recent work on INs has focused on subtypes distinguished by
Externí odkaz:
https://doaj.org/article/1e7eaad566384ed8b027e49abf08e865
Akademický článek
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Autor:
Ravindra Pramod Deshpande, Sambad Sharma, Yin Liu, Puspa Raj Pandey, Xinhong Pei, Kerui Wu, Shih-Ying Wu, Abhishek Tyagi, Dan Zhao, Yin-Yuan Mo, Kounosuke Watabe
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-18 (2022)
Abstract Background Ductal carcinoma in situ (DCIS) of breast is the noninvasive lesion that has propensity to progress to the malignant form. At present, it is still unknown which lesions can potentially progress to invasive forms. In this study, we
Externí odkaz:
https://doaj.org/article/cb0079ca5b124fc885bf2bbcc3779d2c
Autor:
Ritian Lin, Caiyun Ma, Leilei Fang, Chunjin Xu, Cui Zhang, Xiaohan Wu, Wei Wu, Ruixin Zhu, Yingzi Cong, Zhanju Liu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1201-1221 (2022)
Background & Aims: TOB1 is an anti-proliferative protein of Tob/BTG family and typically involved in the tumorigenesis and T cell activation. Although TOB1 is associated with T helper 17 cell–related autoimmunity, its role in modulating T cell–me
Externí odkaz:
https://doaj.org/article/e51c608249b1448ab4029f2c53668b9c
Autor:
Aneta Pankow, Xiao-Hong Sun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T cells develop in the thymus from lymphoid primed multipotent progenitors or common lymphoid progenitors into αβ and γδ subsets. The basic helix-loop-helix transcription factors, E proteins, play pivotal roles at multiple stages from T cell comm
Externí odkaz:
https://doaj.org/article/5250fd590ae2478d819f66066eb8fcf2
Akademický článek
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Autor:
LIU Hong-xian, YANG Jun
Publikováno v:
Jichu yixue yu linchuang, Vol 41, Iss 5, Pp 623-629 (2021)
Objective To investigate the role of inhibitor of DNA binding-2 (ID2) in pulmonary vasculature formation in early lung development. Methods CRISPR/Cas9 system was used to edit ID2 in human embryonic stem cells (hESCs) to construct ID2 knockout strain
Externí odkaz:
https://doaj.org/article/5d3ce9eec30e43b18bae0f548f9cb0bf