Zobrazeno 1 - 10
of 174
pro vyhledávání: '"ICOS LIGAND"'
Autor:
Steven D. Levin, Lawrence S. Evans, Susan Bort, Erika Rickel, Katherine E. Lewis, Rebecca P. Wu, Joseph Hoover, Sean MacNeil, David La, Martin F. Wolfson, Mark W. Rixon, Stacey R. Dillon, Michael G. Kornacker, Ryan Swanson, Stanford L. Peng
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Externí odkaz:
https://doaj.org/article/bed901c0bf43422ba8dc0a6914b60717
Akademický článek
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Autor:
Ib Jarle Christensen, Camilla Bjørnbak Holst, Petra Hamerlik, Jane Skjøth-Rasmussen, Kristoffer Vitting-Seerup, Hans Skovgaard Poulsen, Julia S. Johansen
Publikováno v:
Holst, C B, Christensen, I J, Vitting-Seerup, K, Skjøth-Rasmussen, J, Hamerlik, P, Poulsen, H S & Johansen, J S 2021, ' Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma ', Neuro-Oncology Advances, vol. 3, no. 1 . https://doi.org/10.1093/noajnl/vdab072
Neuro-oncology Advances
Neuro-oncology Advances
Background CNS immune privilege has been challenged in recent years. Glioblastoma (GBM) immune dysfunction includes complex interactions with the immune system outside the CNS. The aim of this study was to determine diagnostic and prognostic potentia
Publikováno v:
British Journal of Dermatology. 182:648-657
Background Atopic dermatitis (AD) is a heterogeneous disease, characterized by excess T helper (Th) 22 activation in Asian AD. Inducible T-cell costimulator (ICOS) is crucial for T-cell activation and differentiation. However, the role of ICOS in AD
Publikováno v:
Journal of Endodontics. 45:890-897
INTRODUCTION The aim was to assess the association of inducible costimulator (ICOS) and ICOS ligand with bone destruction in apical periodontitis (AP). METHODS Specimens from patients presenting with AP were obtained during apicoectomy and subjected
Autor:
Vasil Peev, Eunsil Hahm, Hyun Lee, Nicholas J. Tardi, Ranadheer R. Dande, Mehmet M. Altintas, Cao Yanxia, Beata Samelko, Kamalika Mukherjee, Steve Mangos, Jochen Reiser, Vincent P. Schmitz, Kwi Hye Koh, Ha Won Lee, David Cimbaluk
Publikováno v:
Journal of Clinical Investigation. 129:1713-1726
Soluble urokinase receptor (suPAR) is a circulatory molecule that activates αvβ3 integrin on podocytes, causes foot process effacement, and contributes to proteinuric kidney disease. While active integrin can be targeted by antibodies and small mol
Publikováno v:
The Journal of Immunology. 202:664-674
The role of ICOS and its ligand (ICOSL) have both been shown to be essential for proper humoral responses as well as autoimmune Ab development in mouse models of lupus. In this paper, we report a specific role for the metalloprotease ADAM10 on B cell
Autor:
Melissa S Jennings, Barbara J. Klocke, Keri M. Kemp, Hubert M. Tse, L.W. Duck, Craig L. Maynard, Casey D. Morrow, Charles O. Elson, Rachel Q Muir, Goo Lee, Ashley E. Landuyt, Samuel I. Blum
Publikováno v:
Proc Natl Acad Sci U S A
Genome-wide association studies have identified ICOSLG, which encodes the inducible costimulator ligand (ICOSLG or ICOSL) as a susceptibility locus for inflammatory bowel disease. ICOSL has been implicated in the enhancement of pattern recognition re
Autor:
Laura Aragoneses-Fenoll, Yutaka Arimura, María Montes-Casado, José M. Rojo, Lucía García-Paredes, Umberto Dianzani, Junji Yagi, Pilar Portolés, Gloria Ojeda
Publikováno v:
Journal of Leukocyte Biology
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
18 p.-8 fig.-1 tab.
The interaction between the T‐lymphocyte costimulatory molecule ICOS and its ligand (ICOS‐L) is needed for efficient immune responses, but expression levels are tightly controlled, as altered expression of ICOS or ICOS‐
The interaction between the T‐lymphocyte costimulatory molecule ICOS and its ligand (ICOS‐L) is needed for efficient immune responses, but expression levels are tightly controlled, as altered expression of ICOS or ICOS‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1577fd377df51b97393bf90038263571
http://hdl.handle.net/10261/230271
http://hdl.handle.net/10261/230271
Akademický článek
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