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pro vyhledávání: '"ICC, intrahepatic cholangiocarcinoma"'
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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 355-372 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Tropomyosin receptor kinase A, B and C (TRKA, TRKB and TRKC), which are well-known members of the cell surface receptor tyrosine kinase (RTK) family, are encoded by the neurotrophic receptor tyrosine kinase 1, 2 and 3 (NTRK1, NTRK2 and NTRK3) genes,
Autor:
Shanshan Zhang, Antonio Cigliano, Xianqiong Liu, Xinhua Song, Jie Zhang, Pan Wang, Yong Zeng, Xin Chen, Matthias Evert, Haichuan Wang, Ke Liu, Diego F. Calvisi, Jingxiao Wang, Hong Wu, Jiaoyuan Jia, Silvia Ribback, Li Che
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 4
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1095-1117 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 4
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1095-1117 (2021)
Background & Aims Yes-associated protein (YAP) and its paralog transcriptional co-activator with post synaptic density protein, drosophila disc large tumor suppressor and zonula occludens-1-binding motif (TAZ) are 2 co-activators downstream of Hippo
Autor:
Bingji Li, Wei Yin, Ying-Hong Shi, Yuli Lin, Yan Song, Qian Cai, Haoyang Luo, Xuguang Yang, Wei-Ren Liu, Rui He, Meng-Xin Tian
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1133-1142 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Desmoplasia is a hallmark of intrahepatic cholangiocarcinoma (ICC), which constitutes a barrier to infiltration of lymphocyte, but not myeloid cells. Given that dense desmoplastic stroma has been reported to be a barrier to infiltration of lymphocyte
Autor:
Zhongzheng Zhu, Huangbin Lu, Hua Yu, Song Gao, Wei Dong, Jianguo Wu, Wen-Ming Cong, Xuejun Chen, Xianling Guo, Hui Dong, Qing Xu, Juemin Fang
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 10, Pp 101168-(2021)
Translational Oncology, Vol 14, Iss 10, Pp 101168-(2021)
Highlights • FGFR2 rearrangement frequency in Chinese cases is only 5.45%. • The first genomic aberration profiling of FGFRs in Chinese cases is presented. • Cases with FGFRs rearrangement have distinct clinical phenotype. • Patients without
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 347-363 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The incidence of hepatocellular carcinoma (HCC) and the mortality resulting from HCC are both increasing. Most patients with HCC are diagnosed at advanced stages when curative treatments are impossible. Current drug therapy extends mean overall survi
Autor:
P.H. Patel, Sophie Doran, R.H. Bhogal, Joerg M. Pollok, S. Zar, William H. Allum, M.A. Chaudry, Long R. Jiao, Sacheen Kumar
Publikováno v:
European Journal of Surgical Oncology
Autor:
Takanori Hasegawa, Masashi Fujita, Hidewaki Nakagawa, Kazuaki Chayama, Shinya Hayami, Hiroko Tanaka, Satoru Miyano, Shu Shimada, Kazuhiro Kakimi, Kaoru Nakano, Masaki Ueno, Seiya Imoto, Hiroki Yamaue, Shinji Tanaka, Rui Yamaguchi, Kazuhiro Maejima, Atsushi Ono, Akihiro Fujimoto, Koji Arihiro, Hiroshi Aikata, Shuto Hayashi
Publikováno v:
EBioMedicine, Vol 53, Iss, Pp-(2020)
EBioMedicine
EBioMedicine
Background: The tumor microenvironment can be classified into immunologically active “inflamed” tumors and inactive “non-inflamed” tumors based on the infiltration of cytotoxic immune cells. Previous studies on liver cancer have reported a su
Autor:
Michelangelo Foti, Olivia Bejuy, Christine Maeder, Marta Correia de Sousa, Monika Gjorgjieva, Claudio De Vito, Laura Rubbia-Brandt, Dobrochna Dolicka, Margot Fournier, Cyril Sobolewski, Didier J. Colin, Flavien Berthou, Perry J. Blackshear
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology (2020)
Cellular and Molecular Gastroenterology and Hepatology (2020)
Background & Aims Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory and oncogenic transcripts. Accordingly, TTP was reported to act as a tumor suppressor in specific cancers. Herein, we investigated how TTP contributes to
Autor:
Seiichi Shimizu, Tsuyoshi Kobayashi, Michinori Hamaoka, Masateru Yamamoto, Hiroyuki Tahara, Shintaro Kuroda, Kentaro Ide, Masahiro Ohira, Hideki Ohdan
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Reflux cholangitis is a common complication of Roux-en-Y choledochojejunostomy. • The patient had recurrent postoperative reflux cholangitis. • There was no stenosis or calculus in choledochojejunostomy anastomosis. • Hepatobilia