Zobrazeno 1 - 6
of 6
pro vyhledávání: '"IAN J. SIPULA"'
Autor:
Bellina A. S. Mushala, Bingxian Xie, Ian J. Sipula, Michael W. Stoner, Dharendra Thapa, Janet R. Manning, Paramesha Bugga, Amber M. Vandevender, Michael J. Jurczak, Iain Scott
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract G-protein coupled receptors (GPCRs) mediate signal transduction from the cellular surface to intracellular metabolic pathways. While the function of many GPCRs has been delineated previously, a significant number require further characteriza
Externí odkaz:
https://doaj.org/article/c29485daa80649a8ab8c95d978674e6e
Autor:
Raja Gopal Reddy Mooli, Dhanunjay Mukhi, Anil K. Pasupulati, Simon S. Evers, Ian J. Sipula, Michael Jurczak, Randy J. Seeley, Yatrik M. Shah, Sadeesh K. Ramakrishnan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1057-1072 (2022)
Background & Aims: Compelling evidence shows that glucagon-like peptide-1 (GLP-1) has a profound effect in restoring normoglycemia in type 2 diabetic patients by increasing pancreatic insulin secretion. Although L-cells are the primary source of circ
Externí odkaz:
https://doaj.org/article/02b6ec9b78e94fa7a0450ec4181773fa
Autor:
Bellina A. S. Mushala, Bingxian Xie, Ian J. Sipula, Michael W. Stoner, Dharendra Thapa, Janet R. Manning, Paramesha Bugga, Amber M. Vandevender, Michael J. Jurczak, Iain Scott
G-protein coupled receptors (GPCRs) mediate signal transduction from the cellular surface to intracellular metabolic pathways. While the function of many GPCRs has been delineated previously, a significant number require further characterization to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee1d7f7fe99ac9cc841d22e8266d6ed
https://doi.org/10.1101/2022.10.29.514377
https://doi.org/10.1101/2022.10.29.514377
Autor:
JEFFREY CHEN, FIONA BELLO, JAKE KASTROLL, AMBER VANDEVENDER, MARTHA PANGBURN, AGUSTIN A. GIL SILVA, IAN J. SIPULA, JONATHAN ALDER, MICHAEL J. JURCZAK
Publikováno v:
Diabetes. 71
Growth differentiation factor 15 (GDF15) is a secreted protein whose cellular expression increases in response to a variety of stimuli, including mitochondrial dysfunction. Plasma GDF15 levels increase with advanced age and positively associate with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f6d6904e76fde01482813129a162c8f
https://doi.org/10.2337/db22-1368-p
https://doi.org/10.2337/db22-1368-p
Autor:
BINGXIAN XIE, ANJANA MURALI, AMBER VANDEVENDER, AGUSTIN A. GIL SILVA, FIONA BELLO, IAN J. SIPULA, NIKOLAOS DEDOUSIS, JONATHAN ALDER, MICHAEL J. JURCZAK
Publikováno v:
Diabetes. 71
Growth and differentiation factor 15 (GDF15) is a stress-induced secreted protein whose plasma levels are increased in obese patients. Recombinant GDF15 reduces body weight (BW) and improves glycemia in obese models, which is largely attributed to ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ab03e85155f2fdf1ed14d31bcdf195c
https://doi.org/10.2337/db22-3-or
https://doi.org/10.2337/db22-3-or
Autor:
Benjamin S Mantell, Maja Stefanovic-Racic, Xiao Yang, Nikolas Dedousis, Ian J Sipula, Robert M O'Doherty
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19831 (2011)
The contribution of natural killer T (NKT) cells to the pathogenesis of metabolic abnormalities of obesity is controversial. While the combined genetic deletion of NKT and CD8(+) T-cells improves glucose tolerance and reduces inflammation, interpreta
Externí odkaz:
https://doaj.org/article/6aa5b945c0a24cd78aa94d53fa4a447f