Data parsing in mass spectrometry imaging using R Studio and Cardinal: A tutorial

Autor: Cameron Shedlock, Katherine Stumpo

Publikováno v: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 23, Iss, Pp 58-70 (2022)
Journal of Mass Spectrometry and Advances in the Clinical Lab

Mass spectrometry imaging (MSI) has emerged as a rapidly expanding field in the MS community. The analysis of large spectral data is further complicated by the added spatial dimension of MSI. A plethora of resources exist for expert users to begin pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd723e80de2b52fdcd62794c13682312
https://doi.org/10.1016/j.jmsacl.2021.12.007

Toxicity of diclofenac sodium salt in Yucatan minipigs (Sus scrofa) following 4 weeks of daily intramuscular administration

Autor: Su-Cheol Han, Hyungsun Kim, Jeong Ho Hwang, Mi-Jin Yang, Hee-Jeong Ahn, Goo-Hwa Kang

Publikováno v: Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 557-570 (2021)

Highlights • Four-week repeated-dose toxicity of intramuscular DSS was studied in minipigs. • DSS administration at ≥10 mg/kg/day causes toxicity and injection-site reaction. • The NOAEL of DSS after 4-week administration was 2 mg/kg/day in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b26ee397ae350858c363f15bad4a7b1
https://doi.org/10.1016/j.toxrep.2021.02.022

Sub-chronic dermal exposure to aircraft engine oils impacts the reproductive organ weights and alters hematological profiles of Sprague Dawley rats

Autor: Isaie Sibomana, David R. Mattie

Publikováno v: Current Research in Toxicology
Current Research in Toxicology, Vol 1, Iss, Pp 12-24 (2020)

There is little data available for the toxicity of used aircraft engine oils relative to their unused (new) versions. This study was conducted to determine if grade 3 (G3) and 4 (G4) aircraft engine oils in their new states (G3-N and G4-N) and their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447324bb6e79e92cb0ee0566919bdcaa
https://doi.org/10.1016/j.crtox.2020.02.001

9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts

Autor: Jamie M. Aye, Raoud Marayati, Laura L. Stafman, Elizabeth A. Beierle, Adele P. Williams, Laura V. Bownes, Colin H. Quinn, Venkatram R. Atigadda, Karina J. Yoon, Jerry E. Stewart

Publikováno v: Translational Oncology, Vol 14, Iss 1, Pp 100893-(2021)
Translational Oncology

Retinoic acid (RA) therapy has been utilized as maintenance therapy for high-risk neuroblastoma, but over half of patients treated with RA relapse. Neuroblastoma stem cell-like cancer cells (SCLCCs) are a subpopulation of cells characterized by the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e0ffc188566ee79402dd188357b638
http://www.sciencedirect.com/science/article/pii/S1936523320303855

SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation

Autor: Gang Wei, Yi-Zhun Zhu, Xinhua Liu, Di Yang, Ting Ni, Fen Long, Jinghua Wang, Qing Wang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1261-1273 (2021)

Neointimal hyperplasia after vascular injury is a representative complication of restenosis. Endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) is involved in the pathogenesis of vascular intimal hyperplasia. PARP16, a member o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3676f4e767ed13ecee8819ada7d766c
https://pubmed.ncbi.nlm.nih.gov/34094832