Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice

Autor: Lucy M.V. Gee, Ben Barron-Millar, Jack Leslie, Claire Richardson, Marco Y.W. Zaki, Saimir Luli, Rachel A. Burgoyne, Rainie I.T. Cameron, Graham R. Smith, John G. Brain, Barbara Innes, Laura Jopson, Jessica K. Dyson, Katherine R.C. McKay, Alexandros Pechlivanis, Elaine Holmes, Rolando Berlinguer-Palmini, Stella Victorelli, George F. Mells, Richard N. Sandford, Jeremy Palmer, John A. Kirby, Christos Kiourtis, Joao Mokochinski, Zoe Hall, Thomas G. Bird, Lee A. Borthwick, Christopher M. Morris, Peter S. Hanson, Diana Jurk, Elizabeth A. Stoll, Fiona E.N. LeBeau, David E.J. Jones, Fiona Oakley

Publikováno v: Gee, L M V, Barron-Millar, B, Leslie, J, Richardson, C, Zaki, M Y W, Luli, S, Burgoyne, R, Cameron, R I T, Smith, G R, Brain, J G, Innes, B, Jopson, L, Dyson, J K, McKay, K R C, Pechlivanis, A, Holmes, E, Berlinguer-Palmini, R, Victorelli, S, Mells, G F, Sandford, R N, Palmer, J, Kirby, J, Kiourtis, C, Mokochinski, J, Hall, Z, Bird, T G, Borthwick, L A, Morris, C, Hanson, P, Jurk, D, Stoll, E, LeBeau, F, Jones, D & Oakley, F 2022, ' Anti-Cholestatic therapy with Obeticholic Acid improves short term memory in bile duct ligated mice ', The American Journal of Pathology . https://doi.org/10.1016/j.ajpath.2022.09.005

Patients with cholestatic liver disease, including those with primary biliary cholangitis, can experience symptoms of impaired cognition or brain fog. This phenomenon remains unexplained and is currently untreatable. Bile duct ligation (BDL) is an es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70d70f37cc3ec34fd9fc440f82313fc

A Comparison of Vaginal Ultrasonic-Guided and Laparoscopic Retrieval of Oocytes for in vitro Fertilization

Autor: P. Renou, Gabor T. Kovacs, J. F. Leeton, C. King, E. C. Wood, Suzan Lenz, G. Baker, P. Shekleton, I.T. Cameron, L. Cushnahan

Publikováno v: Asia-Oceania Journal of Obstetrics and Gynaecology. 16:39-43

A retrospective analysis was undertaken to compare the less invasive technique of vaginal ultrasonic-guided oocyte retrieval with the standard laparoscopic technique. We have shown that the outcome of the transvaginal technique with respect to oocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8544b2ad0c4ae59790823489ce11273
https://doi.org/10.1111/j.1447-0756.1990.tb00213.x

Measurements of the dielectric properties of peripheral blood mononuclear cells and trophoblast cells using AC electrokinetic techniques

Autor: M.R Thomas, I.T Cameron, K.L Chan, Hywel Morgan, Edward T. Morgan

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1500:313-322

The separation of trophoblast cells from the maternal circulation could provide a valuable diagnostic tool for prenatal diagnosis of genetic abnormalities. This has been attempted using antibody methods, but due to non-specificity of the antibodies,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e806a1b2f06eae843831ae13b8d2a36
https://doi.org/10.1016/s0925-4439(99)00115-5

Randomised trial of nitric oxide donor versus prostaglandin for cervical ripening before first-trimester termination of pregnancy

Autor: Ian A. Greer, C. Burnett Lunan, Jane E. Norman, Marie-Anne Ledingham, Andrew J. Thomson, Robert C. L. Howat, I.T. Cameron

Publikováno v: The Lancet. 352:1093-1096

Vaginal administration of the nitric oxide donor isosorbide mononitrate can induce effective ripening of the human cervix. We investigated whether this drug is associated with fewer side-effects than prostaglandins when used to ripen the cervix befor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a9305b59b968f07bebe7734018004e
https://doi.org/10.1016/s0140-6736(98)01289-6

Nitric oxide in the human uterus

Autor: Jane E. Norman, I.T. Cameron

Publikováno v: Reviews of Reproduction. 1:61-68

In 1987, the gas nitric oxide (NO) was shown to possess the physical and pharmacological properties of Furchgott’s endothelium-derived relaxing factor (EDRF). It is now recognized that this ubiquitous molecule plays a crucial role in a host of biol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db367b90f065ccf8fbdb25f41e0e5b69
https://doi.org/10.1530/ror.0.0010061