Zobrazeno 1 - 10
of 121
pro vyhledávání: '"I.R. Wilding"'
Autor:
I.R. Wilding, Stephen P. Newman
Publikováno v:
International Journal of Pharmaceutics. 170:1-9
Classical bioequivalence testing, based upon equal rates and extents of drug absorption, is inappropriate for showing equivalence of products containing inhaled asthma drugs, which act directly on the airway surface. The non-invasive imaging techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5cbb00e120db31774c6346f87794d27
https://doi.org/10.1016/s0378-5173(98)00029-5
https://doi.org/10.1016/s0378-5173(98)00029-5
Publikováno v:
Journal of Pharmaceutical Sciences. 87:531-535
□ Colonic drug delivery is intended for local or systemic therapies. The lack of predictive in vitro or animal model leads to considerable time delays in colonic product development. The objective of this scintigraphic study was to provide “proof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8247f9f40bc06c2ae85756115e04e22
https://doi.org/10.1021/js9704588
https://doi.org/10.1021/js9704588
Autor:
P. Rubin, James Alan Schriver Nightingale, V. Tipnis, G.H. Rimoy, I.R. Wilding, S.S. Davis, Bret Berner, Tamie Kurihara-Bergstrom
Publikováno v:
International Journal of Pharmaceutics. 132:81-87
Transdermal delivery of the synthetic opiate analgesic, buprenorphine, was studied in healthy volunteers. Pharmacokinetic, safety and tolerability data were obtained in a group of 12 healthy subjects following administration of a short intravenous in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d67b9eff54c34b397a44ec5471e401df
https://doi.org/10.1016/0378-5173(96)85198-2
https://doi.org/10.1016/0378-5173(96)85198-2
Publikováno v:
Journal of Controlled Release. 33:89-97
The gastrointestinal transit and in vivo release behaviour of a modified release (Geomatrix®) diltiazem formulation has been evaluated by the combined technique of gamma scintigraphy and pharmacokinetic assessment (pharmacoscintigraphy) in eight hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072d5f235cc9de617f1b6408b25d71f0
https://doi.org/10.1016/0168-3659(94)00066-4
https://doi.org/10.1016/0168-3659(94)00066-4
Publikováno v:
International Journal of Pharmaceutics. 112:207-213
Eight healthy volunteers were entered into a randomised, open crossover study to investigate the in vivo behaviour of an enteric coated starch capsule. A radiolabelled preparation was administered to each volunteer on two occasions separated by 7 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a5e612913fc132639c0e6c0cd9d5c8a
https://doi.org/10.1016/0378-5173(94)90356-5
https://doi.org/10.1016/0378-5173(94)90356-5
Publikováno v:
International Journal of Pharmaceutics. 112:199-206
Eight healthy male volunteers were recruited for a study to determine the in vivo behaviour of an enteric coated, modified release beclomethasone dipropionate formulation. The non-invasive technique of gamma scintigraphy was used to relate position a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a23c26ecc40f826907736c57c9427fa
https://doi.org/10.1016/0378-5173(94)90355-7
https://doi.org/10.1016/0378-5173(94)90355-7
Publikováno v:
International Journal of Pharmaceutics. 111:99-102
The gastrointestinal transit and disintegration characteristics of an enteric coated timed release formulation were investigated in a group of six healthy volunteers using the technique of gamma scintigraphy. The mean in vivo tablet disintegration ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08071c141027eee1611aa8e56418a4ca
https://doi.org/10.1016/0378-5173(94)90406-5
https://doi.org/10.1016/0378-5173(94)90406-5
Publikováno v:
Journal of Controlled Release. 31:99-108
A hydrophobic material and surfactant coating for an oral dosage form, which allows for rapid drug release after a predetermined lag time, is described. The pulsed release system has the advantage of being manufactured using conventional film coating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1f2c4658d76e2b70dd429b1dff8635
https://doi.org/10.1016/0168-3659(94)90255-0
https://doi.org/10.1016/0168-3659(94)90255-0
Publikováno v:
Pharmacology & Therapeutics. 62:97-124
Targeted delivery to the gastrointestinal tract requires a multi-disciplinary approach to research involving contributions from polymer and material scientists, gastroenterologists, pharmaceutical scientists and technologists. Intestinal delivery is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3084d1d87f152852644e10659d428206
https://doi.org/10.1016/0163-7258(94)90006-x
https://doi.org/10.1016/0163-7258(94)90006-x
Publikováno v:
International Journal of Pharmaceutics. 101:263-268
The distribution in the gastrointestinal tract of a radiolabelled drug-resinate formulation, administered in the form of an oral suspension, and the concomitantly administered water wash, was investigated using the technique of dual-isotope gamma sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::746f4818fd6ca8d28e8637e584b0c756
https://doi.org/10.1016/0378-5173(94)90222-4
https://doi.org/10.1016/0378-5173(94)90222-4