Zobrazeno 1 - 10 of 191 pro vyhledávání: '"I.P. Lapin"'
2
Anxiolytic Effect of Indole-3-Pyruvic Acid (IPA) in Mice
Autor: V. Politi, I.P. Lapin
Publikováno v: Pharmacological Research. 28:129-134
In an elevated plus-maze indole-3-pyruvic acid (IPA, 100-200mg/kg), an endogenous metabolite of tryptophan, possesses in mice an activity typical of anxiolytics. IPA increased the ratio of the number of entries into open arms over the total number of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd572012896948c0095a9ccd36b24890
https://doi.org/10.1006/phrs.1993.1115
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3
Modulation of the inhibitory effect of phenylethylamine on spontaneous motor activity in mice by CPP-(+/-)-3-(2-carboxypiperazin-4-YL)-propyl-1-phosphonic acid
Autor: I.P Lapin, Arthur Yuwiler
Publikováno v: Pharmacology, biochemistry, and behavior. 56(2)
Beta-phenyl-ethylamine (PEA) at dose of 50 mg/kg inhibits spontaneous, motor activity in mice. CPP- (+/-)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a selective and competitive antagonist of N-methyl-D-aspartate (NMDA) receptors, in doses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae872578c359b8685f02aa528eff07db
https://pubmed.ncbi.nlm.nih.gov/9050075
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4
Only controls: effect of handling, sham injection, and intraperitoneal injection of saline on behavior of mice in an elevated plus-maze
Autor: I.P. Lapin
Publikováno v: Journal of pharmacological and toxicological methods. 34(2)
In male NIH-Swiss mice intraperitoneal injection of physiological saline significantly diminished (vs. naive mice) the ratio of the number of entries into open arms over the sum of entries into open and closed arms, and significantly prolonged time s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadf3422ef65e1c8c80cd9913bcaadc3
https://pubmed.ncbi.nlm.nih.gov/8563035
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8
Convulsions and tremor in immature rats after intraperitoneal injection of kynurenine and its metabolites
Autor: I.P. Lapin
Publikováno v: Pharmacological Research Communications. 10:81-84
Summary L-kynurenine sulfate, quinolinic and nicotinic acids injected intraperitoneally to 7–8-days old, 11–12-days old and 14-days old rats produced tremor, clonic convulsions and tonic twisting of the trunk. The same doses of kynurenines were i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b94ef84fd09348605c439e9df29536
https://doi.org/10.1016/s0031-6989(78)80065-4
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9
Influence of lesions of the amygdaloid complex on behaviour and on effects of antidepressants in rats
Autor: L.H. Allikmets, I.P. Lapin
Publikováno v: International Journal of Neuropharmacology. 6:99-108
Summary It has been ascertained in experiments on amygdaloectomized (AER) and false-operated (FOR) rats that bilateral lesion of amygdaloid complex suppressed emotional reactions (squeak, aggressiveness) but stimulated exploratory motor activity. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::048e127f85e7d8b79d38b6291db15e31
https://doi.org/10.1016/0028-3908(67)90058-5
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