Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I.Michael Goonewardene"'
Publikováno v:
Mechanisms of Ageing and Development. 83:103-116
We have previously demonstrated that age-related declines in Concanavalin A (ConA), induced proliferation and lymphokine production, occur in ad-libitum fed Brown Norway (AL BN) rats. Since caloric restriction (CR) extends lifespan, we expected that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa8e72473456e16af55df7a09b18da0
https://doi.org/10.1016/0047-6374(95)01609-4
https://doi.org/10.1016/0047-6374(95)01609-4
Monocyte culture and adherence modifies LPS-induced IL-6 production and inhibition by hydrocortisone
Publikováno v:
Clinical immunology and immunopathology. 72(2)
The effect of hydrocortisone (HC) on IL-6 production by monocytes (Mo) that were cultured under either adherent or limited-adherent culture conditions was determined. Although freshly isolated Mo produced more IL-6 in response to LPS than Mo cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db1d7cfb304b1fe22fadb9022744b41
https://pubmed.ncbi.nlm.nih.gov/8050200
https://pubmed.ncbi.nlm.nih.gov/8050200
Publikováno v:
Mechanisms of ageing and development. 71(3)
The long-lived, inbred Brown Norway (BN) rat demonstrates an age associated decrease in lymphoproliferation in response to ConA; however, these declines only become apparent after the age of median survival, 31 months. Significant declines in IL-2 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e39de249928e405c5947aaa2c1414d1
https://pubmed.ncbi.nlm.nih.gov/7510811
https://pubmed.ncbi.nlm.nih.gov/7510811
Publikováno v:
Experimental cell research. 199(2)
Lymphocytes have a finite and predictable proliferative life span in culture similar to that observed in fibroblasts. In general, the senescence of human fibroblasts is inevitable and irreversible, but their proliferative life span can be extended by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1473330ab537e95593ac714fac35cf62
https://pubmed.ncbi.nlm.nih.gov/1544379
https://pubmed.ncbi.nlm.nih.gov/1544379
Publikováno v:
Special Focus on the Biology of Aging ISBN: 9783662376522
There are numerous medical problems that become more prevalent with increasing age. Among these are increased incidence of cancer, infectious diseases, and autoimmune syndromes (Makinodan & Kay, 1980). The increase in all three of these conditions ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cad524a483e8792d60676f5c3a5934c2
https://doi.org/10.1007/978-3-662-38445-9_5
https://doi.org/10.1007/978-3-662-38445-9_5
