Zobrazeno 1 - 10
of 79
pro vyhledávání: '"I.M. Varndell"'
Autor:
Kazuhiro Takahashi, J.M. Polak, Anne E. Bishop, Gonzalo Moscoso, S.R. Bloom, M. A. Ghatei, C Escrig, I.M. Varndell, Hiroshi Inagaki
Publikováno v:
Gut. 33:212-217
The distribution of immunoreactivity for the potent vasoconstrictor endothelin-1 was studied in adult and developing human gut using antisera to endothelin-1 (1-21) and the C terminus of big endothelin-1. The coexistence of these peptides with other
Autor:
I.M. Varndell, R. F Power, Anne E. Bishop, R. Holm, J.M. Polak, Douglas Hanahan, Susan Alpert, O. D Madsen
Publikováno v:
Ultrastructural Pathology. 12:547-559
This paper reports on an ultrastructural and electron-microscopic immunocytochemical study of pancreatic B cells from normal mice, pancreatic B cells and derivative tumors from transgenic mice, and tissue from human pancreatic B-cell tumors. In norma
Publikováno v:
Histochemistry. 81:597-601
The neuropeptide tyrosine precursor (pre-pro-NPY) messenger RNA (mRNA) has been localised in formaldehyde-fixed human phaeochromocytoma tissue using a sensitive in situ hybridisation procedure and a novel single-stranded cDNA probe. The reaction prod
Publikováno v:
Journal of Histochemistry & Cytochemistry. 33:1080-1086
The distribution of peptide immunoreactivities predicted from the sequence of the human preproglucagon gene in enteroglucagon (EG; glicentin-like immunoreactant-containing) cells of the human gut and A cells of the pancreas has been determined by lig
Autor:
J.M. Polak, J. Gu, I.M. Varndell, L. Probert, J. De Mey, S.R. Bloom, Alison M.J. Buchan, F.J. Tapia
Publikováno v:
Peptides. 3:259-272
The use of protein A- and IgG-conjugated colloidal gold staining methods for the immuno-localisation of peptide hormones and neurotransmitters at light- and electron microscope level are described and discussed. Bright-field and dark-ground illuminat
Autor:
John Wharton, J. V. Anderson, J.M. Polak, Nicos D. Christofides, S.R. Bloom, Pilar Viñas, I.M. Varndell
Publikováno v:
Neuropeptides. 7:159-173
Specific antibodies to alpha 1–28 atrial natriuretic peptide have been raised and used for radioimmunoassay of tissue extracts and for light and electron microscopic immunocytochemistry. The radioimmunoassay has been used to quantitate ANP-immunore
Autor:
Toru Kameya, Barry S. Wilson, Krishan L. Sikri, Qutayba Hamid, I.M. Varndell, Stephen R. Bloom, Julia M. Polak, Bruce A.J. Ponder, Ricardo V. Lloyd
Publikováno v:
Cancer. 56:2481-2491
The current study was undertaken on 25 cases of thyroid medullary carcinoma to compare the diagnostic value of calcitonin with other peptides including PDN-21, the C-terminal flanking peptide of human calcitonin within the calcitonin precursor, and c
Publikováno v:
Peptides. 6:1237-1243
Neuropeptide tyrosine (NPY) is one of the most abundant and widespread peptides in the mammalian nervous system. Recent isolation and sequencing of the DNA encoding NPY has predicted the existence of a 97 amino acid precursor peptide. Proteolytic pro
Autor:
A. Ali-Rachedi, N. Ling, L. P. C. Schot, J.M. Polak, I.M. Varndell, S. Van Noorden, S.R. Bloom, G.-L. Ferri
Publikováno v:
Neuroendocrinology. 37:427-433
The presence of gamma 1-MSH has been demonstrated in bovine neuro-intermediate lobe by biochemical methods, thus suggesting that this peptide is cleaved from the cryptic region of pro-opiocortin. In this study we report the localisation of gamma 1-MS
Autor:
I.M. Varndell
Publikováno v:
Archiv für Protistenkunde. 123:382-390
Summary Haplosporidium malacobdellae, an Ascetosporan endoparasite previously reported from the entocommensal bdellonemertean Malacobdella grossa is described from a new host, the free-living intertidal hoplonemertean Amphiporus ladifloreus. It is su